LOCUS EU826561 1626 bp mRNA linear HUM 23-JUL-2008
DEFINITION Homo sapiens soluble VEGFR1 variant 21 (VEGFR1) mRNA, complete cds,
alternatively spliced.
ACCESSION EU826561
VERSION EU826561.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1626)
AUTHORS Jin,P., Zhang,J., Sumariwalla,P.F., Ni,I., Jorgensen,B.,
Crawford,D., Phillips,S., Feldmann,M., Shepard,H.M. and
Paleolog,E.M.
TITLE Novel splice variants derived from the receptor tyrosine kinase
superfamily are potential therapeutics for rheumatoid arthritis
JOURNAL Arthritis Res. Ther. 10 (4), R73 (2008)
PUBMED 18593464
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 1626)
AUTHORS Jin,P., Zhang,J., Ni,I. and Shepard,H.M.
TITLE Direct Submission
JOURNAL Submitted (15-JUN-2008) Receptor Biologix, 3350 West Bayshore Road,
Ste. 150, Palo Alto, CA 94303, USA
FEATURES Location/Qualifiers
source 1..1626
/db_xref="H-InvDB:HIT000558146"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="13"
gene 1..1626
/gene="VEGFR1"
CDS 1..1626
/gene="VEGFR1"
/note="alternatively spliced; extracellular domain"
/codon_start=1
/product="soluble VEGFR1 variant 21"
/protein_id="ACF47597.1"
/translation="MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQ
AGQTLHLQCRGEAAHKWSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHT
GFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRV
TSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKT
NYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRA
SVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFI
TVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLII
KDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQ
ILTCTAYGIPQPTIKWFWHPCNHNHSEARCDFCSNNEESFILDADSNMGNRIESITQR
MAIIEGKNKLPPANSSFMLPPTSFSSNYFHFLP"
BASE COUNT 516 a 381 c 327 g 402 t
ORIGIN
1 atggtcagct actgggacac cggggtcctg ctgtgcgcgc tgctcagctg tctgcttctc
61 acaggatcta gttcaggttc aaaattaaaa gatcctgaac tgagtttaaa aggcacccag
121 cacatcatgc aagcaggcca gacactgcat ctccaatgca ggggggaagc agcccataaa
181 tggtctttgc ctgaaatggt gagtaaggaa agcgaaaggc tgagcataac taaatctgcc
241 tgtggaagaa atggcaaaca attctgcagt actttaacct tgaacacagc tcaagcaaac
301 cacactggct tctacagctg caaatatcta gctgtaccta cttcaaagaa gaaggaaaca
361 gaatctgcaa tctatatatt tattagtgat acaggtagac ctttcgtaga gatgtacagt
421 gaaatccccg aaattataca catgactgaa ggaagggagc tcgtcattcc ctgccgggtt
481 acgtcaccta acatcactgt tactttaaaa aagtttccac ttgacacttt gatccctgat
541 ggaaaacgca taatctggga cagtagaaag ggcttcatca tatcaaatgc aacgtacaaa
601 gaaatagggc ttctgacctg tgaagcaaca gtcaatgggc atttgtataa gacaaactat
661 ctcacacatc gacaaaccaa tacaatcata gatgtccaaa taagcacacc acgcccagtc
721 aaattactta gaggccatac tcttgtcctc aattgtactg ctaccactcc cttgaacacg
781 agagttcaaa tgacctggag ttaccctgat gaaaaaaata agagagcttc cgtaaggcga
841 cgaattgacc aaagcaattc ccatgccaac atattctaca gtgttcttac tattgacaaa
901 atgcagaaca aagacaaagg actttatact tgtcgtgtaa ggagtggacc atcattcaaa
961 tctgttaaca cctcagtgca tatatatgat aaagcattca tcactgtgaa acatcgaaaa
1021 cagcaggtgc ttgaaaccgt agctggcaag cggtcttacc ggctctctat gaaagtgaag
1081 gcatttccct cgccggaagt tgtatggtta aaagatgggt tacctgcgac tgagaaatct
1141 gctcgctatt tgactcgtgg ctactcgtta attatcaagg acgtaactga agaggatgca
1201 gggaattata caatcttgct gagcataaaa cagtcaaatg tgtttaaaaa cctcactgcc
1261 actctaattg tcaatgtgaa accccagatt tacgaaaagg ccgtgtcatc gtttccagac
1321 ccggctctct acccactggg cagcagacaa atcctgactt gtaccgcata tggtatccct
1381 caacctacaa tcaagtggtt ctggcacccc tgtaaccata atcattccga agcaaggtgt
1441 gacttttgtt ccaataatga agagtccttt atcctggatg ctgacagcaa catgggaaac
1501 agaattgaga gcatcactca gcgcatggca ataatagaag gaaagaataa gcttccacca
1561 gctaacagtt ctttcatgtt gccacctaca agcttctctt ccaactactt ccatttcctt
1621 ccgtga
//