LOCUS EU822950 7233 bp mRNA linear HUM 29-MAR-2013
DEFINITION Homo sapiens RNA binding protein (RBM20) mRNA, complete cds.
ACCESSION EU822950
VERSION EU822950.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7233)
AUTHORS Guo,W., Schafer,S., Greaser,M.L., Radke,M.H., Liss,M.,
Govindarajan,T., Maatz,H., Schulz,H., Li,S., Parrish,A.M.,
Dauksaite,V., Vakeel,P., Klaassen,S., Gerull,B., Thierfelder,L.,
Regitz-Zagrosek,V., Hacker,T.A., Saupe,K.W., Dec,G.W.,
Ellinor,P.T., MacRae,C.A., Spallek,B., Fischer,R., Perrot,A.,
Ozcelik,C., Saar,K., Hubner,N. and Gotthardt,M.
TITLE RBM20, a gene for hereditary cardiomyopathy, regulates titin
splicing
JOURNAL Nat. Med. 18 (5), 766-773 (2012)
PUBMED 22466703
REFERENCE 2 (bases 1 to 7233)
AUTHORS Guo,W. and Greaser,M.L.
TITLE Direct Submission
JOURNAL Submitted (13-JUN-2008) Animal, University of Wisconsin-Madison,
1805 Linden Drive, Madison, WI 53706, USA
FEATURES Location/Qualifiers
source 1..7233
/db_xref="H-InvDB:HIT000558141"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10q25.2"
gene 1..7233
/gene="RBM20"
5'UTR 1..58
/gene="RBM20"
CDS 59..3742
/gene="RBM20"
/codon_start=1
/product="RNA binding protein"
/protein_id="ACF49364.1"
/translation="MVLAAAMSQDADPSGPEQPDRVACSVPGARASPAPSGPRGMQQP
PPPPQPPPPPQAGLPQIIQNAAKLLDKNPFSVSNPNPLLPSPASLQLAQLQAQLTLHR
LKLAQTAVTNNTAAATVLNQVLSKVAMSQPLFNQLRHPSVITGPHGHAGVPQHAAAIP
STRFPSNAIAFSPPSQTRGPGPSMNLPNQPPSAMVMHPFTGVMPQTPGQPAVILGIGK
TGPAPATAGFYEYGKASSGQTYGPETDGQPGFLPSSASTSGSVTYEGHYSHTGQDGQA
AFSKDFYGPNSQGSHVASGFPAEQAGGLKSEVGPLLQGTNSQWESPHGFSGQSKPDLT
AGPMWPPPHNQPYELYDPEEPTSDRTPPSFGGRLNNSKQGFIGAGRRAKEDQALLSVR
PLQAHELNDFHGVAPLHLPHICSICDKKVFDLKDWELHVKGKLHAQKCLVFSENAGIR
CILGSAEGTLCASPNSTAVYNPAGNEDYASNLGTSYVPIPARSFTQSSPTFPLASVGT
TFAQRKGAGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEA
AQAMVQYYQEKSAVINGEKLLIRMSKRYKELQLKKPGKAVAAIIQDIHSQRERDMFRE
ADRYGPERPRSRSPVSRSLSPRSHTPSFTSCSSSHSPPGPSRADWGNGRDSWEHSPYA
RREEERDPAPWRDNGDDKRDRMDPWAHDRKHHPRQLDKAELDERPEGGRPHREKYPRS
GSPNLPHSVSSYKSREDGYYRKEPKAKWDKYLKQQQDAPGRSRRKDEARLRESRHPHP
DDSGKEDGLGPKVTRAPEGAKAKQNEKNKTKRTDRDQEGADDRKENTMAENEAGKEEQ
EGMEESPQSVGRQEKEAEFSDPENTRTKKEQDWESESEAEGESWYPTNMEELVTVDEV
GEEEDFIVEPDIPELEEIVPIDQKDKICPETCLCVTTTLDLDLAQDFPKEGVKAVGNG
AAEISLKSPRELPSASTSCPSDMDVEMPGLNLDAERKPAESETGLSLEDSDCYEKEAK
GVESSDVHPAPTVQQMSSPKPAEERARQPSPFVDDCKTRGTPEDGACEGSPLEEKASP
PIETDLQNQACQEVLTPENSRYVEMKSLEVRSPEYTEVELKQPLSLPSWEPEDVFSEL
SIPLGVEFVVPRTGFYCKLCGLFYTSEETAKMSHCRSAVHYRNLQKYLSQLAEEGLKE
TEGADSPRPEDSGIVPRFERKKL"
3'UTR 3743..7233
/gene="RBM20"
BASE COUNT 1892 a 1816 c 1858 g 1667 t
ORIGIN
1 ccgggaccgc ccctcccttg agctctctcg ccgcgatccc gggcgggtct cgccccgcat
61 ggtgctggca gcagccatga gccaggacgc ggaccccagc ggtccggagc agccggacag
121 agttgcctgc agtgtgcctg gtgcccgggc gtccccggca ccctccggcc cgcgagggat
181 gcagcagccg ccgccgccgc cccagccacc gcccccgccc caagccggcc taccccagat
241 catccaaaat gccgccaagc tcctggacaa gaacccattc tcggtcagta acccgaaccc
301 tctgcttcct tcacctgcca gtctccagct ggctcaactg caggcccagc tcaccctcca
361 ccggctgaag ctggcacaga cagctgtcac caacaacact gcagccgcca cagtcctgaa
421 ccaagtcctc tccaaagtgg ccatgtccca gcctctcttc aatcaactga ggcatccgtc
481 tgtgatcact ggcccccacg gccatgctgg ggttccccaa catgctgcag ccatacccag
541 tacccggttt ccctctaatg caattgcctt ttcacccccc agccagacac gaggccccgg
601 accctccatg aaccttccca accagccacc cagtgccatg gtgatgcatc ctttcactgg
661 ggtaatgcct cagacccctg gccagccagc agtcatcttg ggcattggca agactgggcc
721 tgctccagct acagcaggat tctatgagta tggcaaagcc agctctggcc agacatatgg
781 ccctgaaaca gatggtcagc ctggcttcct gccatcctcg gcctcaacct cgggcagtgt
841 gacctatgaa gggcactaca gccacacagg gcaggatggt caagctgcct tttccaaaga
901 tttttacgga cccaactccc aaggttcaca tgtggccagc ggatttccag ctgagcaggc
961 tgggggcctg aaaagtgagg tcgggccact gctgcagggc acaaacagcc aatgggagag
1021 cccccatgga ttctcgggcc aaagcaagcc tgatctcaca gcaggtccca tgtggcctcc
1081 accccacaac cagccctatg agctgtacga ccccgaggaa ccaacctcag acaggacacc
1141 tccttccttc gggggtcggc ttaacaacag caaacagggt tttatcggtg ctgggcggag
1201 ggccaaggag gaccaggcgt tgctatctgt gcggcccctg caggctcatg agctgaacga
1261 ctttcacggt gtggcccccc tccacttgcc gcatatctgt agcatctgtg acaagaaggt
1321 gtttgatttg aaggactggg agctgcatgt gaaagggaag ctgcacgctc agaaatgcct
1381 ggtcttctct gaaaatgctg gcatccggtg tatacttggt tcggcagagg gaacattgtg
1441 tgcttctccc aacagcacag ctgtttataa ccctgctggg aatgaagatt atgcctcaaa
1501 tcttggaaca tcatacgtgc ccattccagc aaggtcattc actcagtcaa gccccacatt
1561 tcctttggct tctgtgggga caacttttgc acagcggaaa ggggctggcc gtgtggtgca
1621 catctgcaat ctccctgaag gaagctgcac tgagaatgac gtcattaacc tggggctgcc
1681 ctttggaaag gtcactaatt acatcctcat gaagtcgact aatcaggcct ttttagagat
1741 ggcttacaca gaagctgcac aggccatggt ccagtattat caagaaaaat ctgctgtgat
1801 caatggtgag aagttgctca ttcggatgtc caagagatac aaggaattgc agctcaagaa
1861 acccgggaag gccgtggctg ccatcatcca ggacatccat tcccagaggg agagggacat
1921 gttccgggaa gcagacagat atggcccaga aaggccgcgg tctcgtagtc cggtgagccg
1981 gtcactctcc ccgaggtccc acactcccag cttcacctcc tgcagctctt cccacagccc
2041 tccgggcccc tcccgggctg actggggcaa tggccgggac tcctgggagc actctcccta
2101 tgccaggagg gaggaagagc gagacccggc tccctggagg gacaacggag atgacaagag
2161 ggacaggatg gacccctggg cacatgatcg caaacaccac ccccggcaac tggacaaggc
2221 tgagttggac gagcgaccag aaggagggag gccccaccgg gagaagtacc cgagatctgg
2281 gtctcccaac ctgccccact ctgtgtccag ctacaaaagc cgtgaagacg gctactaccg
2341 gaaagagccc aaagccaagt gggacaagta tctgaagcag cagcaggatg cccccgggag
2401 gtccaggagg aaagacgagg ccaggctgcg ggaaagcaga cacccccatc cggatgactc
2461 aggcaaggaa gatgggctgg ggccaaaggt cactagggcc cctgagggcg ccaaggccaa
2521 gcagaatgag aaaaataaaa ccaagagaac tgatagagac caagaaggag ctgatgatag
2581 aaaagaaaac acaatggcag agaatgaggc tggaaaagag gaacaggagg gcatggaaga
2641 aagccctcaa tcagtgggca gacaggagaa agaagcagag ttctctgatc cggaaaacac
2701 aaggacaaag aaggaacaag attgggagag tgaaagtgag gcagaggggg agagctggta
2761 tcccactaac atggaggagc tggtgacagt ggacgaggtt ggggaagaag aagattttat
2821 cgtggaacca gacatcccag agctggaaga aattgtgccc attgaccaga aagacaaaat
2881 ttgcccagaa acatgtctgt gtgtgacaac caccttagac ttagacctgg cccaggattt
2941 ccccaaggaa ggagtcaagg ccgtagggaa tggggctgca gaaatcagcc tcaagtcacc
3001 cagagaactg ccctctgctt ccacaagctg tcccagtgac atggacgtgg aaatgcctgg
3061 cctaaatctg gatgctgagc ggaagccagc tgaaagtgag acaggcctct ccctggagga
3121 ttcagattgc tacgagaagg aggcaaaggg agtggagagc tcagatgttc atccagcccc
3181 tacagtccag caaatgtctt cccctaagcc agcagaggag agggcccggc agccaagccc
3241 atttgtggat gattgcaaga ccagggggac ccccgaagat ggggcttgtg aaggcagccc
3301 cctggaggag aaagccagcc cccccatcga aactgacctc caaaaccaag cttgccaaga
3361 agtgttgacc ccggaaaact ccaggtacgt ggaaatgaaa tctctggagg tgaggtcacc
3421 agagtacact gaagtggaac tgaaacagcc cctttctttg ccctcttggg aaccagagga
3481 tgtgttcagt gaacttagca ttcctctagg ggtggagttc gtggttccca ggactggctt
3541 ttattgcaag ctgtgtgggc tgttctacac gagcgaggag acagcaaaga tgagccactg
3601 ccgcagcgct gtccactaca ggaacttaca gaaatatttg tcccagctgg ccgaggaggg
3661 cctcaaggag accgaggggg cagatagccc gaggccagag gacagcggaa tcgtgccacg
3721 cttcgaaagg aaaaagctct gatgcttctg cttctgctgc tactgctgct gctgcaaggt
3781 tggaaaggag agcttgctga agtggggcct tcctgattct ggggacagga ctaaagcctg
3841 agaggaagga aaaccaagca gggcacattg cttgggcttg ttcccagaga ctcagtgaaa
3901 tgcccctgat atgtctccag gagcaagtca cccaggtgtg tccagcccac tgagggtcac
3961 caactctctc cctgctgact cttgtttctc tcaatctttc aattcgtttt tctctctttt
4021 cctcttgttc tttctctccc tccctcctta tgtgccaagg atcgtttcct tttcacaaaa
4081 cccaacttct cagggatttt cacagtgttt aaattcttgg taggatataa caggtcaggc
4141 ctagctgagt caggcaagga aaaggtttaa tggaaactcc tgggtcaggc gaacccctgc
4201 agtgagtcta cagcagtatc tctgcctggt gtcccatgta tcccctgcat gaggagctga
4261 gtcaggtctg cagtcctggt gaggggacat cacggacaat ctgttggcag agctgggagg
4321 gtcttcatta acctcttcct ccaactgggc cacccttttg aaaagcccct gtttttaata
4381 actgtttcat cctctcagtt attctagaaa tctgccagac ttatgcctta aagtaaaatt
4441 aaatgaattt tagagaagat gaaaagagcc cttcattttg gaagctctga taagtttcct
4501 ccaaacttat tcccctcctc ttgatttcag gagatgtcag ggtttttcta ttctggacaa
4561 tgaatttggt acagagtcac tgtaattaaa tataaaaaca gaagcatctt cctccagcta
4621 aagcagcagt tggcgcgggc ttaggttgaa tgctggcctc tctgcaaagc acagctttgg
4681 ctcgagaggc acagctccag gctgtggaaa acagagttgt cttgggggtt aaatgagctt
4741 atttaagtca aggaaacatc atctgtcctt gattcagcct tggtgcctgc actctggggt
4801 acaaccacct cacagtagga tggtttttaa atggcccccc agttggggga gaagctaagg
4861 aaagagaagg ctgcagatcc aaagagtggc attgaagttt gctgggtgtc tgtaggtgga
4921 ccctttccag ctgggcagat agttgagggc tccctgggtt tgactgtatg tgcagacttt
4981 gataccaaaa tgttatgaaa agtcgtgatt cccgctgctc tttctggtac tggagggtgg
5041 gtaccttcag gctgtggggt ctctagcctg atattccatt gaaagggtgt gggataaagg
5101 tgctggggga aatgaggctc tgccacagcc atagagaggc cctcgggcag ttaagaaggg
5161 agcctggagc tgttttcatg agcagagata ctctcctgaa agcacccttc atagcttagc
5221 ccaggaaaaa taaaacaagg aagacaggtc actctcccct aggcagttcc tgttgtttct
5281 gttcctgacc ttgggcaggc agactgagaa gggactgtgt agggttttgt tttgtttttt
5341 ttcattttcc tttttatggc atgtgagagc atactgtaca ttctgtcctc tgtactaatg
5401 gaggaagggc agagagatta gttcaaggct aacattttat atcaggtaac tgaggcacac
5461 aaagggaaca aatgaagaac ataaaatgat cagtgtaaac ctgaaagcac gcagtcattg
5521 gcaagggaca ggctcatggg agctggtgag agagagcagt taaggcaagc accaggggaa
5581 agcagaccaa cttgaacaga tgtgatgcgg agaggttgga agaagcaaga aacctgaact
5641 catcatcagg ctattaaata aaatttatag gaggctgttg gtttggactg agctcctgca
5701 ataggcccaa cagaccaaaa caaaagggag tcactcatgt tgaagttctg tcttccagga
5761 aatcaggaga gagagagaga gaaagaatag ccaaatcccc aaacaggcca gttttaacca
5821 gcatgatgaa gtgtccttgg ttttaacctt tataaggaaa gcagctttga gatgaccagt
5881 ctggtttttg ttctttgtgt ctgctttcct cagccctttt ctgtctataa agccaacctc
5941 ctccgctcag ctcatgggaa cactcattct attttataga atgacatgtt gcccaattct
6001 agaatcaaaa ataaaggcca actaagatct tcaaagtaaa tttgttgtaa ttttatcttt
6061 tgagaagacc atatgggggc tgctgaaaag ttggtatctc aaataaagtc tgaagatcac
6121 ggctcagccc agattgttcc cctggccaac tccacaggtt tgaacctggc attctggaca
6181 ccagctatgc ctcctccatt tctcagaaaa cctttgatct tgtgtgtctt tcttcctact
6241 gaagggaatt gtgggggcag ttctttggcc ttcttgctga actttgctgg aaatagccca
6301 caatttttat cagaggttag aactgtacat tatcagagag actggacact ttatccccta
6361 gcaaagtggg agaagatttt accagctcat tccactccac cctggccttc ccccaccccc
6421 catccccagc agcatttcca tggaaatcca gatggtcgtg tagtgttatg gctctcttgt
6481 gatagactgg ccttcatatt ggagagctag ggagagcccc tgggagggag agagataagg
6541 cgctatctgc cttcaatcag aaccttcggt ttaaaatcat ctaagagtct atacttgtgt
6601 gtacatacgt atttattttt atttattttt atacaattcc attggcatgg tccttcaccg
6661 accctatgat ttgcactttt tatttctatg tgtgccacac acaatgcagt attaatggca
6721 accaggtaaa tattgattta ttttttaaag cttttcttca gtgttttgtc aaccatttca
6781 aagtgtctcc caaaaaagga tgctgaagag caattgctcc cttaagcaac agattcatat
6841 ttaccctggg ttaatacaac aaaaggcctg tataattgtc ttttcattgt taacacccaa
6901 aatagcatct atctagacag tatccccaaa gaatttggaa aatctgatgg tgtgagcagc
6961 agccgttagt atcagggttt cccattcttg gacagtccga ggctgtgacc tgttagataa
7021 ttagattata cttgaactgg accagagttt gttttttgaa tttatgagaa aaaccaaaac
7081 actaagttaa gtttgaactt gtaaagtatt gaaatttgtt gagtgtccta taaattgtca
7141 ctacttttcc tgatctgtat aactgactgc aaagtgtttg tttttacaaa agagaaaaga
7201 aaagattttt aataaagaga atttgaaagc tgt
//