LOCUS EU416199 1539 bp mRNA linear HUM 16-MAR-2009
DEFINITION Homo sapiens islet cell autoantigen 1 isoform (ICA1) mRNA, complete
cds, alternatively spliced.
ACCESSION EU416199
VERSION EU416199.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1539)
AUTHORS Hoehne,M., Lorscheider,J., Schermer,B. and Benzing,T.
TITLE A new transcript variant of human ICA69
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1539)
AUTHORS Hoehne,M., Lorscheider,J., Schermer,B. and Benzing,T.
TITLE Direct Submission
JOURNAL Submitted (18-JAN-2008) Renal Division, University Hospital
Cologne, Kerpener Str. 62, Koeln 50937, Germany
FEATURES Location/Qualifiers
source 1..1539
/db_xref="H-InvDB:HIT000557769"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="7"
/cell_type="islet"
/tissue_type="brain"
/dev_stage="fetus"
/PCR_primers="fwd_seq: cgcgggacgcgtatgtcaggacacaaatgcag,
rev_seq: cgtagagcggccgcctcatgcattgagcaattcgtg"
gene 1..1539
/gene="ICA1"
CDS 1..1539
/gene="ICA1"
/note="69kDa isoform; alternatively spliced"
/codon_start=1
/product="islet cell autoantigen 1 isoform"
/protein_id="ACB47390.1"
/translation="MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKK
EDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQG
FQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRME
QCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDL
LGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKK
LVEKEEKKKINQQESTDAAVQEPSQYLQNICLEMKANSDIKMLQKGKEGQQIGILISL
EEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAGTP
EPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHE
LLNA"
exon 903..989
/gene="ICA1"
/note="alternative exon between exons 10 and 11 annotated
in NM_022307.2"
BASE COUNT 493 a 326 c 369 g 351 t
ORIGIN
1 atgtcaggac acaaatgcag ttatccctgg gacttacagg atcgatatgc tcaagataag
61 tcagttgtaa ataagatgca acagaaatat tgggagacga agcaggcctt tattaaagcc
121 acagggaaga aggaagatga acatgttgtt gcctctgacg cggacctgga tgccaagcta
181 gagctgtttc attcaattca gagaacctgt ctggacttat cgaaagcaat tgtactctat
241 caaaagagga tatgtttctt gtctcaagaa gaaaacgaac tgggaaaatt tcttcgatcc
301 caaggtttcc aagataaaac cagagcagga aagatgatgc aagcgacagg aaaggccctc
361 tgcttttctt cccagcaaag gttggcctta cgaaatcctt tgtgtcgatt tcaccaagaa
421 gtggagactt ttcggcatcg ggccatctca gatacttggc tgacggtgaa ccgcatggaa
481 cagtgcagga cggaatatag aggagcacta ttatggatga aggacgtgtc tcaggagctt
541 gatccagacc tctacaagca aatggagaag ttcaggaagg tacaaacaca agtgcgcctt
601 gcaaaaaaaa actttgacaa attgaagatg gatgtttgtc aaaaagtgga tcttcttgga
661 gcgagcagat gcaatctctt gtctcacatg ctagcaacat accagaccac tctgcttcat
721 ttttgggaga aaacttctca cactatggca gccatccatg agagtttcaa aggttatcaa
781 ccatatgaat ttactacttt aaagagctta caagacccta tgaaaaaatt agttgagaaa
841 gaagagaaga agaaaatcaa ccagcaggaa agtacagatg cagccgtgca ggagccgagc
901 caatatttac agaatatttg cctcgagatg aaagcaaatt cagatattaa gatgctacag
961 aaagggaaag aaggccagca aattggcata ttaatttcat tagaggaaga aaaccagcgc
1021 aaggaatcct ctagttttaa gactgaagat ggaaaaagta ttttatctgc cttagacaaa
1081 ggctctacac atactgcatg ctcaggaccc atagatgaac tattagacat gaaatctgag
1141 gaaggtgctt gcctgggacc agtggcaggg accccggaac ctgaaggtgc tgacaaagat
1201 gacctgctgc tgttgagtga gatcttcaat gcttcctcct tggaagaggg cgagttcagc
1261 aaagagtggg ccgctgtgtt tggagacggc caagtgaagg agccagtgcc cactatggcc
1321 ctgggagagc cagaccccaa ggcccagaca ggctcaggtt tccttccttc gcagctttta
1381 gaccaaaata tgaaagactt acaggcctcg ctacaagaac ctgctaaggc tgcctcagac
1441 ctgactgcct ggttcagcct cttcgctgac ctcgacccac tctcaaatcc tgatgctgtt
1501 gggaaaaccg ataaagaaca cgaattgctc aatgcatga
//