LOCUS EU265737 1406 bp mRNA linear HUM 25-MAY-2011
DEFINITION Homo sapiens numb isoform 8 (NUMB) mRNA, complete cds,
alternatively spliced.
ACCESSION EU265737
VERSION EU265737.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1406)
AUTHORS Haider,M., Qiu,Q., Bani-Yaghoub,M., Tsang,B.K. and Gruslin,A.
TITLE Characterization and role of NUMB in the human extravillous
trophopblast
JOURNAL Placenta 32 (6), 441-449 (2011)
PUBMED 21486681
REFERENCE 2 (bases 1 to 1406)
AUTHORS Haider,M., Qiu,Q., Bani-Yaghoub,M. and Gruslin,A.
TITLE Characterization of Numb and Its Novel Isoforms in the Human
Placenta
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 1406)
AUTHORS Qiu,Q., Bani-Yaghoub,M. and Haider,M.
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2007) Hormones, Growth and Development Program,
Ottawa Health Research Institute, 725 Parkdale Avenue, Ottawa, ON
K1Y 4E9, Canada
FEATURES Location/Qualifiers
source 1..1406
/db_xref="H-InvDB:HIT000484784"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="placenta"
/PCR_primers="fwd_seq: ggcacagccaagattcagagc, rev_seq:
tggacaagatacatagccataatgattgc"
gene 1..1406
/gene="NUMB"
CDS 40..1377
/gene="NUMB"
/note="alternatively spliced"
/codon_start=1
/product="numb isoform 8"
/protein_id="ABY89093.1"
/translation="MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYL
GHVEVDESRGMHICEDAVKRLKATGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEK
VSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQK
REKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKGTEWGQSSGAA
SPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPF
QGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG
TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLA
SADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL"
BASE COUNT 365 a 373 c 347 g 321 t
ORIGIN
1 ggcacagcca agattcagag ccaggctgta aaaattaaaa tgaacaaatt acggcaaagt
61 tttaggagaa agaaggatgt ttatgttcca gaggccagtc gtccacatca gtggcagaca
121 gatgaagaag gcgttcgcac cggaaaatgt agcttcccgg ttaagtacct tggccatgta
181 gaagttgatg aatcaagagg aatgcacatc tgtgaagatg ctgtaaaaag attgaaagct
241 actggaaaga aagcagttaa agcagttctg tgggtctcag cagatggact cagagttgtg
301 gatgaaaaaa ctaaggacct catagttgac cagacgatag agaaagtttc tttctgtgcc
361 ccagacagga actttgatag agccttttct tacatatgcc gtgatggcac cactcgtcgc
421 tggatctgtc actgcttcat ggctgtcaag gacacaggtg aaaggttgag ccatgcagta
481 ggctgtgctt ttgcagcctg tttagagcgc aagcagaagc gggagaagga atgtggagtg
541 actgctactt ttgatgctag tcggaccact tttacaagag aaggatcatt ccgtgtcaca
601 acagccactg aacaagcaga aagagaggag atcatgaaac aaatgcaaga tgccaagaaa
661 gggaccgagt ggggtcaatc ttctggtgct gcctctccag gtctcttcca ggccggtcat
721 agacgtactc cctctgaggc cgaccgatgg ttagaagagg tgtctaagag cgtccgggct
781 cagcagcccc aggcctcagc tgctcctctg cagccagttc tccagcctcc tccacccact
841 gccatctccc agccagcatc acctttccaa gggaatgcat tcctcacctc tcagcctgtg
901 ccagtgggtg tggtcccagc cctgcaacca gcctttgtcc ctgcccagtc ctatcctgtg
961 gccaatggaa tgccctatcc agcccctaat gtgcctgtgg tgggcatcac tccctcccag
1021 atggtggcca acgtatttgg cactgcaggc caccctcagg ctgcccatcc ccatcagtca
1081 cccagcctgg tcaggcagca gacattccct cactacgagg caagcagtgc taccaccagt
1141 cccttcttta agcctcctgc tcagcacctc aacggttctg cagctttcaa tggtgtagat
1201 gatggcaggt tggcctcagc agacaggcat acagaggttc ctacaggcac ctgcccagtg
1261 gatccttttg aagcccagtg ggctgcatta gaaaataagt ccaagcagcg tactaatccc
1321 tcccctacca accctttctc cagtgactta cagaagacgt ttgaaattga actttaagca
1381 atcattatgg ctatgtatct tgtcca
//