LOCUS EU265736 1439 bp mRNA linear HUM 25-MAY-2011
DEFINITION Homo sapiens numb isoform 7 (NUMB) mRNA, complete cds,
alternatively spliced.
ACCESSION EU265736
VERSION EU265736.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1439)
AUTHORS Haider,M., Qiu,Q., Bani-Yaghoub,M., Tsang,B.K. and Gruslin,A.
TITLE Characterization and role of NUMB in the human extravillous
trophopblast
JOURNAL Placenta 32 (6), 441-449 (2011)
PUBMED 21486681
REFERENCE 2 (bases 1 to 1439)
AUTHORS Haider,M., Qiu,Q., Bani-Yaghoub,M., Tsang,B.K. and Gruslin,A.
TITLE Characterization of Numb and Its Novel Isoforms in the Human
Placenta
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 1439)
AUTHORS Qiu,Q., Bani-Yaghoub,M., Haider,M., Tsang,B.K. and Gruslin,A.
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2007) Hormones, Growth and Development Program,
Ottawa Health Research Institute, 725 Parkdale Avenue, Ottawa, ON
K1Y 4E9, Canada
FEATURES Location/Qualifiers
source 1..1439
/db_xref="H-InvDB:HIT000484783"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="placenta"
/PCR_primers="fwd_seq: ggcacagccaagattcagagc, rev_seq:
tggacaagatacatagccataatgattgc"
gene 1..1439
/gene="NUMB"
CDS 40..1410
/gene="NUMB"
/note="alternatively spliced"
/codon_start=1
/product="numb isoform 7"
/protein_id="ABY89092.1"
/translation="MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYL
GHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKT
KDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGC
AFAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKK
GTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPP
PTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGI
TPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSA
AFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQK
TFEIEL"
BASE COUNT 377 a 377 c 355 g 330 t
ORIGIN
1 ggcacagcca agattcagag ccaggctgta aaaattaaaa tgaacaaatt acggcaaagt
61 tttaggagaa agaaggatgt ttatgttcca gaggccagtc gtccacatca gtggcagaca
121 gatgaagaag gcgttcgcac cggaaaatgt agcttcccgg ttaagtacct tggccatgta
181 gaagttgatg aatcaagagg aatgcacatc tgtgaagatg ctgtaaaaag attgaaagct
241 gaaaggaagt tcttcaaagg cttctttgga aaaactggaa agaaagcagt taaagcagtt
301 ctgtgggtct cagcagatgg actcagagtt gtggatgaaa aaactaagga cctcatagtt
361 gaccagacga tagagaaagt ttctttctgt gccccagaca ggaactttga tagagccttt
421 tcttacatat gccgtgatgg caccactcgt cgctggatct gtcactgctt catggctgtc
481 aaggacacag gtgaaaggtt gagccatgca gtaggctgtg cttttgcagc ctgtttagag
541 cgcaagcaga agcgggagaa ggaatgtgga gtgactgcta cttttgatgc tagtcggacc
601 acttttacaa gagaaggatc attccgtgtc acaacagcca ctgaacaagc agaaagagag
661 gagatcatga aacaaatgca agatgccaag aaagggaccg agtggggtca atcttctggt
721 gctgcctctc caggtctctt ccaggccggt catagacgta ctccctctga ggccgaccga
781 tggttagaag aggtgtctaa gagcgtccgg gctcagcagc cccaggcctc agctgctcct
841 ctgcagccag ttctccagcc tcctccaccc actgccatct cccagccagc atcacctttc
901 caagggaatg cattcctcac ctctcagcct gtgccagtgg gtgtggtccc agccctgcaa
961 ccagcctttg tccctgccca gtcctatcct gtggccaatg gaatgcccta tccagcccct
1021 aatgtgcctg tggtgggcat cactccctcc cagatggtgg ccaacgtatt tggcactgca
1081 ggccaccctc aggctgccca tccccatcag tcacccagcc tggtcaggca gcagacattc
1141 cctcactacg aggcaagcag tgctaccacc agtcccttct ttaagcctcc tgctcagcac
1201 ctcaacggtt ctgcagcttt caatggtgta gatgatggca ggttggcctc agcagacagg
1261 catacagagg ttcctacagg cacctgccca gtggatcctt ttgaagccca gtgggctgca
1321 ttagaaaata agtccaagca gcgtactaat ccctccccta ccaacccttt ctccagtgac
1381 ttacagaaga cgtttgaaat tgaactttaa gcaatcatta tggctatgta tcttgtcca
//