LOCUS EU265735 1553 bp mRNA linear HUM 01-MAR-2008
DEFINITION Homo sapiens numb isoform 6 (NUMB) mRNA, complete cds,
alternatively spliced.
ACCESSION EU265735
VERSION EU265735.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1553)
AUTHORS Haider,M., Qiu,Q., Bani-Yaghoub,M., Tsang,B.K. and Gruslin,A.
TITLE Characterization of Numb and Its Novel Isoforms in the Human
Placenta
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1553)
AUTHORS Qiu,Q., Bani-Yaghoub,M., Haider,M., Tsang,B.K. and Gruslin,A.
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2007) Hormones, Growth and Development Program,
Ottawa Health Research Institute, 725 Parkdale Avenue, Ottawa, ON
K1Y 4E9, Canada
FEATURES Location/Qualifiers
source 1..1553
/db_xref="H-InvDB:HIT000484782"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="placenta"
/PCR_primers="fwd_seq: ggcacagccaagattcagagc, rev_seq:
tggacaagatacatagccataatgattgc"
gene 1..1553
/gene="NUMB"
CDS 40..1524
/gene="NUMB"
/note="alternatively spliced"
/codon_start=1
/product="numb isoform 6"
/protein_id="ABY89091.1"
/translation="MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYL
GHVEVDESRGMHICEDAVKRLKATGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEK
VSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQK
REKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKVPEVEGEAESI
SSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGH
RRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQ
PVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAH
PHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVP
TGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL"
BASE COUNT 404 a 421 c 380 g 348 t
ORIGIN
1 ggcacagcca agattcagag ccaggctgta aaaattaaaa tgaacaaatt acggcaaagt
61 tttaggagaa agaaggatgt ttatgttcca gaggccagtc gtccacatca gtggcagaca
121 gatgaagaag gcgttcgcac cggaaaatgt agcttcccgg ttaagtacct tggccatgta
181 gaagttgatg aatcaagagg aatgcacatc tgtgaagatg ctgtaaaaag attgaaagct
241 actggaaaga aagcagttaa agcagttctg tgggtctcag cagatggact cagagttgtg
301 gatgaaaaaa ctaaggacct catagttgac cagacgatag agaaagtttc tttctgtgcc
361 ccagacagga actttgatag agccttttct tacatatgcc gtgatggcac cactcgtcgc
421 tggatctgtc actgcttcat ggctgtcaag gacacaggtg aaaggttgag ccatgcagta
481 ggctgtgctt ttgcagcctg tttagagcgc aagcagaagc gggagaagga atgtggagtg
541 actgctactt ttgatgctag tcggaccact tttacaagag aaggatcatt ccgtgtcaca
601 acagccactg aacaagcaga aagagaggag atcatgaaac aaatgcaaga tgccaagaaa
661 gtgccagaag tagaagggga ggcagagagc atcagctccc tgtgctcaca gatcaccaat
721 gccttcagca cacctgagga ccccttctca tctgctccga tgaccaaacc agtgacagtg
781 gtggcaccac aatctcctac cttccaaggg accgagtggg gtcaatcttc tggtgctgcc
841 tctccaggtc tcttccaggc cggtcataga cgtactccct ctgaggccga ccgatggtta
901 gaagaggtgt ctaagagcgt ccgggctcag cagccccagg cctcagctgc tcctctgcag
961 ccagttctcc agcctcctcc acccactgcc atctcccagc cagcatcacc tttccaaggg
1021 aatgcattcc tcacctctca gcctgtgcca gtgggtgtgg tcccagccct gcaaccagcc
1081 tttgtccctg cccagtccta tcctgtggcc aatggaatgc cctatccagc ccctaatgtg
1141 cctgtggtgg gcatcactcc ctcccagatg gtggccaacg tatttggcac tgcaggccac
1201 cctcaggctg cccatcccca tcagtcaccc agcctggtca ggcagcagac attccctcac
1261 tacgaggcaa gcagtgctac caccagtccc ttctttaagc ctcctgctca gcacctcaac
1321 ggttctgcag ctttcaatgg tgtagatgat ggcaggttgg cctcagcaga caggcataca
1381 gaggttccta caggcacctg cccagtggat ccttttgaag cccagtgggc tgcattagaa
1441 aataagtcca agcagcgtac taatccctcc cctaccaacc ctttctccag tgacttacag
1501 aagacgtttg aaattgaact ttaagcaatc attatggcta tgtatcttgt cca
//