LOCUS EU048203 2380 bp mRNA linear HUM 27-NOV-2007
DEFINITION Homo sapiens antisense fragile X mental retardation protein variant
A (ASFMR1) mRNA, complete cds, alternatively spliced.
ACCESSION EU048203
VERSION EU048203.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2380)
AUTHORS Ladd,P.D., Smith,L.E., Rabaia,N.A., Moore,J.M., Georges,S.A.,
Hansen,R.S., Hagerman,R.J., Tassone,F., Tapscott,S.J. and
Filippova,G.N.
TITLE An antisense transcript spanning the CGG repeat region of FMR1 is
upregulated in premutation carriers but silenced in full mutation
individuals
JOURNAL Hum. Mol. Genet. 16 (24), 3174-3187 (2007)
PUBMED 17921506
REFERENCE 2 (bases 1 to 2380)
AUTHORS Ladd,P.D., Smith,L.E., Rabaia,N.A., Moore,J.M., Tapscott,S.J. and
Filippova,G.N.
TITLE Direct Submission
JOURNAL Submitted (19-JUL-2007) Human Biology, Fred Hutchinson Cancer
Research Center, 1100 Fairview Ave North, Seattle, WA 98109, USA
FEATURES Location/Qualifiers
source 1..2380
/db_xref="H-InvDB:HIT000484293"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq27.3"
/tissue_type="normal lymphocytes"
gene 1..2380
/gene="ASFMR1"
CDS 206..508
/gene="ASFMR1"
/note="ASFMRP; antisense transcript overlaps the fragile X
mental retardation gene 1; alternatively spliced"
/codon_start=1
/product="antisense fragile X mental retardation protein
variant A"
/protein_id="ABV80256.1"
/translation="MNILYKCLVESAIGAPHFHHQLLHLLFSPASAGSPPPRGGLRAL
EAQPPPPPPPPPPPPPPPPPPPPRCRTPPGSGASVTAAARARRRPAARSEAALHRK"
BASE COUNT 600 a 612 c 547 g 621 t
ORIGIN
1 cagtcattcc attagtttaa tactgagttg ttcagaaact tctcagtcag taacatgaag
61 atccattcct gaaaagcact caaactggac ttgaattttt aaaaaatgaa gaatagaatt
121 agcataaaat attaaagaac ctcatcatta aaattatata acgagacact tacttgtttt
181 caaatgcaac tgttattgaa tcttcatgaa catcctttac aaatgccttg tagaaagcgc
241 cattggagcc ccgcacttcc accaccagct cctccatctt ctcttcagcc ctgctagcgc
301 cgggagcccg cccccgagag gtgggctgcg ggcgctcgag gcccagccgc cgccgccgcc
361 gccgccgccg ccgcctccgc cgccgccgcc gccgccgccg ccgccgcgct gccgcacgcc
421 ccctggcagc ggcgcctccg tcaccgccgc cgcccgcgct cgccgtcggc ccgccgcccg
481 ctcagaggcg gccctccacc ggaagtgaaa ccgaaacgga gctgagcgcc tgactgaggc
541 cgaacccccg gcccgctgcg ggtgtaaaca ctgaaaccac gtcacgtgat caacgctgtt
601 ccctcccccc gcgggctcag cccctcggcc ccgccctctc tcttcaagtg gcctgggagc
661 gcgcgcatgc gcgctgctgg gaaccggccg gggtgccggg tcgaaagaca gacgcgcggg
721 ccgggcgtgc gcgggcttgg tggagggcgg gaaggctgaa gggcggtgac aggtcgcact
781 gcctcgcgag ggccagaacg cccatttctg cagagctgcc ttaatccatg ttcccttcgg
841 gatgctggta tccaactgag aagttgacgg agcatctatc gtgtgccaga cactgtgcta
901 agtgctaacg agaaatcggt gagcaaaaca gaaaagaaaa aaaaagaaga aacgactgcc
961 agcattgaac ttagtaccta gcaaagtagg tggacataaa tcaaattgtc agacaagtaa
1021 atgagtagtt gcagctgtga taaggggtat gaagaatagg cgcttccatg atggcggaac
1081 atgacctagt ctggggtgga gaaggggaga tgattccagc tggaatatgg caggtgagag
1141 ttaactaata gcactgagtt ggcagaggca ggatgacctg ccccaggcag gtgccccaga
1201 atgagaggat gttgctgctg gtggaactcc agctttaaag cggtggatct agggccacat
1261 tcctcaaggc catagcaaac aggaaagacc ttttggacta gggtctttgg agtagtcaca
1321 tgaggccaag aacccaatag ggctgaaaga gaatctcatc ataggctgaa tgggagcaga
1381 gcattagctg caactccaat gtattatagt aaaaggggac acattgatta gaatgattat
1441 acccctccaa gtgtaagctg ttgttcaatt tacccagggc ttaaaaatat gtcaactctt
1501 cacaaccatt tttactacaa gccacactca acctgtgttg ttccctgaac ctgtgatgca
1561 ctttcatccg ttcatgtctc tacacatcct tcctgggccc catagaggcc ctgcacctta
1621 aggttttcag ctggattcct attagctagt tattttatct caggtacaga gagttaactt
1681 tgctcctcaa ttttcagcac attgtcatat cagtccctac agggtccttg tttacattat
1741 tttatagtgt ttatattatt ttttcctcat ctttctcgat ccccactctc attcttctag
1801 acacaagctg caatatgttc gatagagatc cttgataatt taacacagat aatgttttgt
1861 ttatgcctct tgcatttaca gagatggtat tggactgtaa atctctattt cccactgttt
1921 tactcaacag tctgtttttg agctataccc acattgctgt gtgtacacct agtttgctac
1981 cgagtatgcc agaaatttta ttcatacata tccctactga tcgggcatct aggttactgc
2041 caactccctg aagtcatact gtggtgaaaa cccttgtgaa tgtctttaca aacctttgcc
2101 agaacttatt ttgtgctctt gtagaacttt gtgcataccc tctgcttcct cattacactg
2161 cttggcatat agcagagact caacaaatgt tgaatacctc tactatgatg gttagtgtac
2221 tagaataatt tatttatatt tctgttttcc ttattggatt attagtacct tccagacagg
2281 gcaaatgtct tttctatctt tgtgtccctg gcacattaaa agtggttgat ttcaaggtat
2341 gttcaatgaa tgaataaata cttatcttca ctgccagtac
//