LOCUS EU048202 2484 bp mRNA linear HUM 27-NOV-2007
DEFINITION Homo sapiens antisense fragile X mental retardation protein variant
B (ASFMR1) mRNA, complete cds, alternatively spliced.
ACCESSION EU048202
VERSION EU048202.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2484)
AUTHORS Ladd,P.D., Smith,L.E., Rabaia,N.A., Moore,J.M., Georges,S.A.,
Hansen,R.S., Hagerman,R.J., Tassone,F., Tapscott,S.J. and
Filippova,G.N.
TITLE An antisense transcript spanning the CGG repeat region of FMR1 is
upregulated in premutation carriers but silenced in full mutation
individuals
JOURNAL Hum. Mol. Genet. 16 (24), 3174-3187 (2007)
PUBMED 17921506
REFERENCE 2 (bases 1 to 2484)
AUTHORS Ladd,P.D., Smith,L.E., Rabaia,N.A., Moore,J.M., Tapscott,S.J. and
Filippova,G.N.
TITLE Direct Submission
JOURNAL Submitted (19-JUL-2007) Human Biology, Fred Hutchinson Cancer
Research Center, 1100 Fairview Ave North, Seattle, WA 98109, USA
FEATURES Location/Qualifiers
source 1..2484
/db_xref="H-InvDB:HIT000484292"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq27.3"
/tissue_type="normal lymphocytes"
gene 1..2484
/gene="ASFMR1"
CDS 206..508
/gene="ASFMR1"
/note="ASFMRP; antisense transcript overlaps the fragile X
mental retardation gene 1; alternatively spliced"
/codon_start=1
/product="antisense fragile X mental retardation protein
variant B"
/protein_id="ABV80255.1"
/translation="MNILYKCLVESAIGAPHFHHQLLHLLFSPASAGSPPPRGGLRAL
EAQPPPPPPPPPPPPPPPPPPPPRCRTPPGSGASVTAAARARRRPAARSEAALHRK"
BASE COUNT 622 a 639 c 578 g 645 t
ORIGIN
1 cagtcattcc attagtttaa tactgagttg ttcagaaact tctcagtcag taacatgaag
61 atccattcct gaaaagcact caaactggac ttgaattttt aaaaaatgaa gaatagaatt
121 agcataaaat attaaagaac ctcatcatta aaattatata acgagacact tacttgtttt
181 caaatgcaac tgttattgaa tcttcatgaa catcctttac aaatgccttg tagaaagcgc
241 cattggagcc ccgcacttcc accaccagct cctccatctt ctcttcagcc ctgctagcgc
301 cgggagcccg cccccgagag gtgggctgcg ggcgctcgag gcccagccgc cgccgccgcc
361 gccgccgccg ccgcctccgc cgccgccgcc gccgccgccg ccgccgcgct gccgcacgcc
421 ccctggcagc ggcgcctccg tcaccgccgc cgcccgcgct cgccgtcggc ccgccgcccg
481 ctcagaggcg gccctccacc ggaagtgaaa ccgaaacgga gctgagcgcc tgactgaggc
541 cgaacccccg gcccgctgcg ggtgtaaaca ctgaaaccac gtcacgtgat caacgctgtt
601 ccctcccccc gcgggctcag cccctcggcc ccgccctctc tcttcaagtg gcctgggagc
661 gcgcgcatgc gcgctgctgg gaaccggccg gggtgccggg tcgaaagaca gacgcgcggg
721 ccgggcgtgc gcgggcttgg tggagggcgg gaaggctgaa gggcggtgac aggtcgcact
781 gcctcgcgag ggccagaacg cccatttctg cagaggcaga aggtgaggcg tctacgccct
841 ctctcaccag attttgggcg gccctgtgga gacaccctgt gccctttaag ggacatggat
901 tgagtcggga tctcaaaatc tgccttaatc catgttccct tcgggatgct ggtatccaac
961 tgagaagttg acggagcatc tatcgtgtgc cagacactgt gctaagtgct aacgagaaat
1021 cggtgagcaa aacagaaaag aaaaaaaaag aagaaacgac tgccagcatt gaacttagta
1081 cctagcaaag taggtggaca taaatcaaat tgtcagacaa gtaaatgagt agttgcagct
1141 gtgataaggg gtatgaagaa taggcgcttc catgatggcg gaacatgacc tagtctgggg
1201 tggagaaggg gagatgattc cagctggaat atggcaggtg agagttaact aatagcactg
1261 agttggcaga ggcaggatga cctgccccag gcaggtgccc cagaatgaga ggatgttgct
1321 gctggtggaa ctccagcttt aaagcggtgg atctagggcc acattcctca aggccatagc
1381 aaacaggaaa gaccttttgg actagggtct ttggagtagt cacatgaggc caagaaccca
1441 atagggctga aagagaatct catcataggc tgaatgggag cagagcatta gctgcaactc
1501 caatgtatta tagtaaaagg ggacacattg attagaatga ttatacccct ccaagtgtaa
1561 gctgttgttc aatttaccca gggcttaaaa atatgtcaac tcttcacaac catttttact
1621 acaagccaca ctcaacctgt gttgttccct gaacctgtga tgcactttca tccgttcatg
1681 tctctacaca tccttcctgg gccccataga ggccctgcac cttaaggttt tcagctggat
1741 tcctattagc tagttatttt atctcaggta cagagagtta actttgctcc tcaattttca
1801 gcacattgtc atatcagtcc ctacagggtc cttgtttaca ttattttata gtgtttatat
1861 tattttttcc tcatctttct cgatccccac tctcattctt ctagacacaa gctgcaatat
1921 gttcgataga gatccttgat aatttaacac agataatgtt ttgtttatgc ctcttgcatt
1981 tacagagatg gtattggact gtaaatctct atttcccact gttttactca acagtctgtt
2041 tttgagctat acccacattg ctgtgtgtac acctagtttg ctaccgagta tgccagaaat
2101 tttattcata catatcccta ctgatcgggc atctaggtta ctgccaactc cctgaagtca
2161 tactgtggtg aaaacccttg tgaatgtctt tacaaacctt tgccagaact tattttgtgc
2221 tcttgtagaa ctttgtgcat accctctgct tcctcattac actgcttggc atatagcaga
2281 gactcaacaa atgttgaata cctctactat gatggttagt gtactagaat aatttattta
2341 tatttctgtt ttccttattg gattattagt accttccaga cagggcaaat gtcttttcta
2401 tctttgtgtc cctggcacat taaaagtggt tgatttcaag gtatgttcaa tgaatgaata
2461 aatacttatc ttcactgcca gtac
//