LOCUS EU048201 2644 bp mRNA linear HUM 27-NOV-2007
DEFINITION Homo sapiens antisense fragile X mental retardation protein variant
C (ASFMR1) mRNA, complete cds, alternatively spliced.
ACCESSION EU048201
VERSION EU048201.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2644)
AUTHORS Ladd,P.D., Smith,L.E., Rabaia,N.A., Moore,J.M., Georges,S.A.,
Hansen,R.S., Hagerman,R.J., Tassone,F., Tapscott,S.J. and
Filippova,G.N.
TITLE An antisense transcript spanning the CGG repeat region of FMR1 is
upregulated in premutation carriers but silenced in full mutation
individuals
JOURNAL Hum. Mol. Genet. 16 (24), 3174-3187 (2007)
PUBMED 17921506
REFERENCE 2 (bases 1 to 2644)
AUTHORS Ladd,P.D., Smith,L.E., Rabaia,N.A., Moore,J.M., Tapscott,S.J. and
Filippova,G.N.
TITLE Direct Submission
JOURNAL Submitted (19-JUL-2007) Human Biology, Fred Hutchinson Cancer
Research Center, 1100 Fairview Ave North, Seattle, WA 98109, USA
FEATURES Location/Qualifiers
source 1..2644
/db_xref="H-InvDB:HIT000484291"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq27.3"
/tissue_type="normal lymphocytes"
gene 1..2644
/gene="ASFMR1"
CDS 206..508
/gene="ASFMR1"
/note="ASFMRP; antisense transcript overlaps the fragile X
mental retardation gene 1; alternatively spliced"
/codon_start=1
/product="antisense fragile X mental retardation protein
variant C"
/protein_id="ABV80254.1"
/translation="MNILYKCLVESAIGAPHFHHQLLHLLFSPASAGSPPPRGGLRAL
EAQPPPPPPPPPPPPPPPPPPPPRCRTPPGSGASVTAAARARRRPAARSEAALHRK"
BASE COUNT 656 a 657 c 645 g 686 t
ORIGIN
1 cagtcattcc attagtttaa tactgagttg ttcagaaact tctcagtcag taacatgaag
61 atccattcct gaaaagcact caaactggac ttgaattttt aaaaaatgaa gaatagaatt
121 agcataaaat attaaagaac ctcatcatta aaattatata acgagacact tacttgtttt
181 caaatgcaac tgttattgaa tcttcatgaa catcctttac aaatgccttg tagaaagcgc
241 cattggagcc ccgcacttcc accaccagct cctccatctt ctcttcagcc ctgctagcgc
301 cgggagcccg cccccgagag gtgggctgcg ggcgctcgag gcccagccgc cgccgccgcc
361 gccgccgccg ccgcctccgc cgccgccgcc gccgccgccg ccgccgcgct gccgcacgcc
421 ccctggcagc ggcgcctccg tcaccgccgc cgcccgcgct cgccgtcggc ccgccgcccg
481 ctcagaggcg gccctccacc ggaagtgaaa ccgaaacgga gctgagcgcc tgactgaggc
541 cgaacccccg gcccgctgcg ggtgtaaaca ctgaaaccac gtcacgtgat caacgctgtt
601 ccctcccccc gcgggctcag cccctcggcc ccgccctctc tcttcaagtg gcctgggagc
661 gcgcgcatgc gcgctgctgg gaaccggccg gggtgccggg tcgaaagaca gacgcgcggg
721 ccgggcgtgc gcgggcttgg tggagggcgg gaaggctgaa gggcggtgac aggtcgcact
781 gcctcgcgag ggccagaacg cccatttctg cagaggtgca ctcagtggcg tgggaaatca
841 aatgcatccg gttatcccag ttcggcctct ctgggattcc gcgggagggg gtgtctggtc
901 tggtttggtt tggtttggtt tggtttggtt tggtccggtt caaagtagcg cagtctgact
961 gagcgggagg tggagtggaa ggcgagaata ggggtgaagg attagacaga agaagacttt
1021 gaactaggaa cagtggcaac cagggtgacc caggcttttg tgacccgtag aggcagaagc
1081 tgccttaatc catgttccct tcgggatgct ggtatccaac tgagaagttg acggagcatc
1141 tatcgtgtgc cagacactgt gctaagtgct aacgagaaat cggtgagcaa aacagaaaag
1201 aaaaaaaaag aagaaacgac tgccagcatt gaacttagta cctagcaaag taggtggaca
1261 taaatcaaat tgtcagacaa gtaaatgagt agttgcagct gtgataaggg gtatgaagaa
1321 taggcgcttc catgatggcg gaacatgacc tagtctgggg tggagaaggg gagatgattc
1381 cagctggaat atggcaggtg agagttaact aatagcactg agttggcaga ggcaggatga
1441 cctgccccag gcaggtgccc cagaatgaga ggatgttgct gctggtggaa ctccagcttt
1501 aaagcggtgg atctagggcc acattcctca aggccatagc aaacaggaaa gaccttttgg
1561 actagggtct ttggagtagt cacatgaggc caagaaccca atagggctga aagagaatct
1621 catcataggc tgaatgggag cagagcatta gctgcaactc caatgtatta tagtaaaagg
1681 ggacacattg attagaatga ttatacccct ccaagtgtaa gctgttgttc aatttaccca
1741 gggcttaaaa atatgtcaac tcttcacaac catttttact acaagccaca ctcaacctgt
1801 gttgttccct gaacctgtga tgcactttca tccgttcatg tctctacaca tccttcctgg
1861 gccccataga ggccctgcac cttaaggttt tcagctggat tcctattagc tagttatttt
1921 atctcaggta cagagagtta actttgctcc tcaattttca gcacattgtc atatcagtcc
1981 ctacagggtc cttgtttaca ttattttata gtgtttatat tattttttcc tcatctttct
2041 cgatccccac tctcattctt ctagacacaa gctgcaatat gttcgataga gatccttgat
2101 aatttaacac agataatgtt ttgtttatgc ctcttgcatt tacagagatg gtattggact
2161 gtaaatctct atttcccact gttttactca acagtctgtt tttgagctat acccacattg
2221 ctgtgtgtac acctagtttg ctaccgagta tgccagaaat tttattcata catatcccta
2281 ctgatcgggc atctaggtta ctgccaactc cctgaagtca tactgtggtg aaaacccttg
2341 tgaatgtctt tacaaacctt tgccagaact tattttgtgc tcttgtagaa ctttgtgcat
2401 accctctgct tcctcattac actgcttggc atatagcaga gactcaacaa atgttgaata
2461 cctctactat gatggttagt gtactagaat aatttattta tatttctgtt ttccttattg
2521 gattattagt accttccaga cagggcaaat gtcttttcta tctttgtgtc cctggcacat
2581 taaaagtggt tgatttcaag gtatgttcaa tgaatgaata aatacttatc ttcactgcca
2641 gtac
//