LOCUS EU048200 3026 bp mRNA linear HUM 27-NOV-2007
DEFINITION Homo sapiens antisense fragile X mental retardation protein variant
D (ASFMR1) mRNA, complete cds, alternatively spliced.
ACCESSION EU048200
VERSION EU048200.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3026)
AUTHORS Ladd,P.D., Smith,L.E., Rabaia,N.A., Moore,J.M., Georges,S.A.,
Hansen,R.S., Hagerman,R.J., Tassone,F., Tapscott,S.J. and
Filippova,G.N.
TITLE An antisense transcript spanning the CGG repeat region of FMR1 is
upregulated in premutation carriers but silenced in full mutation
individuals
JOURNAL Hum. Mol. Genet. 16 (24), 3174-3187 (2007)
PUBMED 17921506
REFERENCE 2 (bases 1 to 3026)
AUTHORS Ladd,P.D., Smith,L.E., Rabaia,N.A., Moore,J.M., Tapscott,S.J. and
Filippova,G.N.
TITLE Direct Submission
JOURNAL Submitted (19-JUL-2007) Human Biology, Fred Hutchinson Cancer
Research Center, 1100 Fairview Ave North, Seattle, WA 98109, USA
FEATURES Location/Qualifiers
source 1..3026
/db_xref="H-InvDB:HIT000484290"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq27.3"
/sex="male"
/tissue_type="normal lymphocytes"
gene 1..3026
/gene="ASFMR1"
CDS 206..508
/gene="ASFMR1"
/note="ASFMRP; antisense transcript overlaps the fragile X
mental retardation gene 1; alternatively spliced"
/codon_start=1
/product="antisense fragile X mental retardation protein
variant D"
/protein_id="ABV80253.1"
/translation="MNILYKCLVESAIGAPHFHHQLLHLLFSPASAGSPPPRGGLRAL
EAQPPPPPPPPPPPPPPPPPPPPRCRTPPGSGASVTAAARARRRPAARSEAALHRK"
BASE COUNT 735 a 762 c 724 g 805 t
ORIGIN
1 cagtcattcc attagtttaa tactgagttg ttcagaaact tctcagtcag taacatgaag
61 atccattcct gaaaagcact caaactggac ttgaattttt aaaaaatgaa gaatagaatt
121 agcataaaat attaaagaac ctcatcatta aaattatata acgagacact tacttgtttt
181 caaatgcaac tgttattgaa tcttcatgaa catcctttac aaatgccttg tagaaagcgc
241 cattggagcc ccgcacttcc accaccagct cctccatctt ctcttcagcc ctgctagcgc
301 cgggagcccg cccccgagag gtgggctgcg ggcgctcgag gcccagccgc cgccgccgcc
361 gccgccgccg ccgcctccgc cgccgccgcc gccgccgccg ccgccgcgct gccgcacgcc
421 ccctggcagc ggcgcctccg tcaccgccgc cgcccgcgct cgccgtcggc ccgccgcccg
481 ctcagaggcg gccctccacc ggaagtgaaa ccgaaacgga gctgagcgcc tgactgaggc
541 cgaacccccg gcccgctgcg ggtgtaaaca ctgaaaccac gtcacgtgat caacgctgtt
601 ccctcccccc gcgggctcag cccctcggcc ccgccctctc tcttcaagtg gcctgggagc
661 gcgcgcatgc gcgctgctgg gaaccggccg gggtgccggg tcgaaagaca gacgcgcggg
721 ccgggcgtgc gcgggcttgg tggagggcgg gaaggctgaa gggcggtgac aggtcgcact
781 gcctcgcgag ggccagaacg cccatttctg cagaggtgca ctcagtggcg tgggaaatca
841 aatgcatccg gttatcccag ttcggcctct ctgggattcc gcgggagggg gtgtctggtc
901 tggtttggtt tggtttggtt tggtttggtt tggtccggtt caaagtagcg cagtctgact
961 gagcgggagg tggagtggaa ggcgagaata ggggtgaagg attagacaga agaagacttt
1021 gaactaggaa cagtggcaac cagggtgacc caggcttttg tgacccgtag aggcagaagg
1081 tgaggcgtct acgccctctc tcaccagatt ttgggcggcc ctgtggagac accctgtgcc
1141 ctttaaggga catggattga gtcgggatct caaaatgtga gcctttcctc agacccagct
1201 ttgacccacg tactcgcctt tcctcaactc attttcatac tttcacttga ctatatattt
1261 tttaaaaatt gtgttaagca cttgaggttc atttctgccc ctactgtatg tgcaccctgt
1321 gccagagggt ggggtgaaca cgtgtgtagc agtcatgcgt cctgtccaca ggggccgatg
1381 cacctccttg caacccttta cattccactg tgaaacaaac ctcaactttt tcttattcct
1441 gtttttacac cgtgcttata gctgccttaa tccatgttcc cttcgggatg ctggtatcca
1501 actgagaagt tgacggagca tctatcgtgt gccagacact gtgctaagtg ctaacgagaa
1561 atcggtgagc aaaacagaaa agaaaaaaaa agaagaaacg actgccagca ttgaacttag
1621 tacctagcaa agtaggtgga cataaatcaa attgtcagac aagtaaatga gtagttgcag
1681 ctgtgataag gggtatgaag aataggcgct tccatgatgg cggaacatga cctagtctgg
1741 ggtggagaag gggagatgat tccagctgga atatggcagg tgagagttaa ctaatagcac
1801 tgagttggca gaggcaggat gacctgcccc aggcaggtgc cccagaatga gaggatgttg
1861 ctgctggtgg aactccagct ttaaagcggt ggatctaggg ccacattcct caaggccata
1921 gcaaacagga aagacctttt ggactagggt ctttggagta gtcacatgag gccaagaacc
1981 caatagggct gaaagagaat ctcatcatag gctgaatggg agcagagcat tagctgcaac
2041 tccaatgtat tatagtaaaa ggggacacat tgattagaat gattataccc ctccaagtgt
2101 aagctgttgt tcaatttacc cagggcttaa aaatatgtca actcttcaca accattttta
2161 ctacaagcca cactcaacct gtgttgttcc ctgaacctgt gatgcacttt catccgttca
2221 tgtctctaca catccttcct gggccccata gaggccctgc accttaaggt tttcagctgg
2281 attcctatta gctagttatt ttatctcagg tacagagagt taactttgct cctcaatttt
2341 cagcacattg tcatatcagt ccctacaggg tccttgttta cattatttta tagtgtttat
2401 attatttttt cctcatcttt ctcgatcccc actctcattc ttctagacac aagctgcaat
2461 atgttcgata gagatccttg ataatttaac acagataatg ttttgtttat gcctcttgca
2521 tttacagaga tggtattgga ctgtaaatct ctatttccca ctgttttact caacagtctg
2581 tttttgagct atacccacat tgctgtgtgt acacctagtt tgctaccgag tatgccagaa
2641 attttattca tacatatccc tactgatcgg gcatctaggt tactgccaac tccctgaagt
2701 catactgtgg tgaaaaccct tgtgaatgtc tttacaaacc tttgccagaa cttattttgt
2761 gctcttgtag aactttgtgc ataccctctg cttcctcatt acactgcttg gcatatagca
2821 gagactcaac aaatgttgaa tacctctact atgatggtta gtgtactaga ataatttatt
2881 tatatttctg ttttccttat tggattatta gtaccttcca gacagggcaa atgtcttttc
2941 tatctttgtg tccctggcac attaaaagtg gttgatttca aggtatgttc aatgaatgaa
3001 taaatactta tcttcactgc cagtac
//