LOCUS       EF710845                 381 bp    mRNA    linear   HUM 28-APR-2011
DEFINITION  Homo sapiens clone 997-L6-12 immunoglobulin lambda light chain
            variable region mRNA, partial sequence.
ACCESSION   EF710845
VERSION     EF710845.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Bellavia,D., Abraham,R.S., Pellikka,P.A., Dispenzieri,A.,
            Burnett,J.C. Jr., Al-Zahrani,G.B., Green,T.D., Manske,M.K.,
            Gertz,M.A., Miller,F.A. Jr. and Abraham,T.P.
  TITLE     Utility of Doppler myocardial imaging, cardiac biomarkers, and
            clonal immunoglobulin genes to assess left ventricular performance
            and stratify risk following peripheral blood stem cell
            transplantation in patients with systemic light chain amyloidosis
            (Al)
  JOURNAL   J Am Soc Echocardiogr 24 (4), 444-454 (2011)
   PUBMED   21315556
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Manske,M.K., Bellavia,D., Dispenzieri,A., Abraham,T.P. and
            Abraham,R.S.
  TITLE     The utility of immunoglobulin light chain V gene analysis and
            echocardiographic strain imaging to predict outcome
            post-hematopoietic stem cell transplant (HSCT) in primary (AL)
            amyloidosis
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 381)
  AUTHORS   Manske,M.K., Bellavia,D., Dispenzieri,A., Abraham,T.P. and
            Abraham,R.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2007) Department of Hematology, Mayo Clinic
            Rochester, 221 4th Ave S.W., Rochester, MN 55905, USA
FEATURES             Location/Qualifiers
     source          1..381
                     /db_xref="H-InvDB:HIT000564328"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /isolation_source="primary systemic amyloidosis (AL)"
                     /db_xref="taxon:9606"
                     /clone="997-L6-12"
                     /tissue_type="BM clonal population"
     gene            <1..>381
                     /gene="immunoglobulin lambda light chain variable region"
                     /note="VL6 6a JL2/3a"
BASE COUNT           75 a          126 c           94 g           86 t
ORIGIN      
        1 gattttatgc tgactcagcc ccactctgtg tcggagtctc cggggaagac ggtaaccatc
       61 tcctgcaccg gcagcagtgg cagcattgcc agcaactatg tgcagtggta ccagcagcgc
      121 ccgggcagtg cccccaccac tgtggtctat gaggataacc aaagaccctc tggggtccct
      181 gatcgattct ctggctccat cgacagctcc tccaactctg cctccctcac catctctgga
      241 ctgaagactg aggacgaggc tgactactac tgtcagtctt atgatagcta caatcatgtt
      301 atattcggcg gggggaccaa gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      361 actctgttcc cgccctcctc t
//