LOCUS EF595686 1512 bp mRNA linear HUM 06-JUN-2007
DEFINITION Homo sapiens cAMP-specific phosphodiesterase-4 B isoform (PDE4B5)
mRNA, complete cds.
ACCESSION EF595686
VERSION EF595686.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1512)
AUTHORS Cheung,Y.F., Kan,Z., Garrett-Engele,P., Gall,I., Murdoch,H.,
Baillie,G.S., Camargo,L.M., Johnson,J.M., Houslay,M.D. and
Castle,J.C.
TITLE PDE4B5, a novel, super-short, brain-specific cAMP
phosphodiesterase-4 variant whose isoform-specifying N-terminal
region is identical to that of cAMP phosphodiesterase-4D6 (PDE4D6)
JOURNAL J. Pharmacol. Exp. Ther. 322 (2), 600-609 (2007)
PUBMED 17519386
REFERENCE 2 (bases 1 to 1512)
AUTHORS Cheung,Y.-F., Kan,Z., Garrett-Engele,P.W., Gall,I., Murdoch,H.,
Baillie,G.S., Camargo,L.M., Johnson,J.M., Houslay,M.D. and
Castle,J.C.
TITLE Direct Submission
JOURNAL Submitted (07-MAY-2007) Genomics, Rosetta/Merck, 401 Terry Ave N,
Seattle, WA 98109, USA
FEATURES Location/Qualifiers
source 1..1512
/db_xref="H-InvDB:HIT000469432"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p31"
gene 1..1512
/gene="PDE4B5"
CDS 1..1512
/gene="PDE4B5"
/codon_start=1
/product="cAMP-specific phosphodiesterase-4 B isoform"
/protein_id="ABQ85407.1"
/translation="MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISN
TFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMM
TLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHP
GVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKM
VIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSN
PTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHP
LWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELT
LDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLGETDIDIATEDKSPVDT"
BASE COUNT 473 a 337 c 343 g 359 t
ORIGIN
1 atgcctgagg caaattattt gttatctgta tcttggggtt acatcaagtt caaaagaatg
61 ctgaaccggg agctgacaca cctctcagag atgagccgat cagggaacca ggtgtctgaa
121 tacatttcaa atactttctt agacaagcag aatgatgtgg agatcccatc tcctacccag
181 aaagacaggg agaaaaagaa aaagcagcag ctcatgaccc agataagtgg agtgaagaaa
241 ttaatgcata gttcaagcct aaacaataca agcatctcac gctttggagt caacactgaa
301 aatgaagatc acctggccaa ggagctggaa gacctgaaca aatggggtct taacatcttt
361 aatgtggctg gatattctca caatagaccc ctaacatgca tcatgtatgc tatattccag
421 gaaagagacc tcctaaagac attcagaatc tcatctgaca catttataac ctacatgatg
481 actttagaag accattacca ttctgacgtg gcatatcaca acagcctgca cgctgctgat
541 gtagcccagt cgacccatgt tctcctttct acaccagcat tagacgctgt cttcacagat
601 ttggagatcc tggctgccat ttttgcagct gccatccatg acgttgatca tcctggagtc
661 tccaatcagt ttctcatcaa cacaaattca gaacttgctt tgatgtataa tgatgaatct
721 gtgttggaaa atcatcacct tgctgtgggt ttcaaactgc tgcaagaaga acactgtgac
781 atcttcatga atctcaccaa gaagcagcgt cagacactca ggaagatggt tattgacatg
841 gtgttagcaa ctgatatgtc taaacatatg agcctgctgg cagacctgaa gacaatggta
901 gaaacgaaga aagttacaag ttcaggcgtt cttctcctag acaactatac cgatcgcatt
961 caggtccttc gcaacatggt acactgtgca gacctgagca accccaccaa gtccttggaa
1021 ttgtatcggc aatggacaga ccgcatcatg gaggaatttt tccagcaggg agacaaagag
1081 cgggagaggg gaatggaaat tagcccaatg tgtgataaac acacagcttc tgtggaaaaa
1141 tcccaggttg gtttcatcga ctacattgtc catccattgt gggagacatg ggcagatttg
1201 gtacagcctg atgctcagga cattctcgat accttagaag ataacaggaa ctggtatcag
1261 agcatgatac ctcaaagtcc ctcaccacca ctggacgagc agaacaggga ctgccagggt
1321 ctgatggaga agtttcagtt tgaactgact ctcgatgagg aagattctga aggacctgag
1381 aaggagggag agggacacag ctatttcagc agcacaaaga cgctttgtgt gattgatcca
1441 gaaaacagag attccctggg agagactgac atagacattg caacagaaga caagtccccc
1501 gtggatacat aa
//