LOCUS EF491870 1275 bp mRNA linear HUM 27-MAR-2008
DEFINITION Homo sapiens intracellular domain VEGFR1 variant 21 mRNA, complete
cds, alternatively spliced.
ACCESSION EF491870
VERSION EF491870.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1275)
AUTHORS Mezquita,B., Mezquita,J., Pau,M. and Mezquita,C.
TITLE A New Family of Truncated Isoforms of VEGFR1 Consisting of the
Intracellular Domains of the Molecule
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1275)
AUTHORS Mezquita,J.
TITLE Direct Submission
JOURNAL Submitted (13-MAR-2007) Physiology, Faculty of Medicine, University
of Barcelona, Casanova 143, Barcelona 08036, Spain
FEATURES Location/Qualifiers
source 1..1275
/db_xref="H-InvDB:HIT000468819"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="MDA-MB-231"
/PCR_primers="fwd_seq: aagcagtggtatcaacgcagagt, rev_seq:
aagctagtttcctgggggtata"
CDS 157..1242
/note="kinase domain; idVEGFR1p21as; alternatively
spliced"
/codon_start=1
/product="intracellular domain VEGFR1 variant 21"
/protein_id="ABS32270.1"
/translation="MNSDLLVDSDGFYKEPITMEDLISYSFQVARGMEFLSSRKCIHR
DLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTK
SDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIMLDCW
HRDPKERPRFAELVEKLGDLLQANVQQDGKDYIPINAILTGNSGFTYSTPAFSEDFFK
ESISAPKFNSGSSDDVRYVNAFKFMSLERIKTFEELLPNATSMFDDYQGDSSTLLASP
MLKRFTWTDSKPKASLKIDLRVTSKSKESGLSDVSRPSFCHSSCGHVSEGKRRFTYDH
AELERKIACCSPPPDYNSVVLYSTPPI"
BASE COUNT 350 a 300 c 297 g 328 t
ORIGIN
1 acagagttac taattttgac agggaactgt accgttttct cccctcaggg attttcatct
61 taatggatca tccccctgcc cccatgcttg gataaagtgg gctggaggcc tggaaaaatc
121 tctggtgttc atgttgaaac tcaaatactc ttaaaaatga actctgatct acttgttgat
181 tctgacggtt tctacaagga gcccatcact atggaagatc tgatttctta cagttttcaa
241 gtggccagag gcatggagtt cctgtcttcc agaaagtgca ttcatcggga cctggcagcg
301 agaaacattc ttttatctga gaacaacgtg gtgaagattt gtgattttgg ccttgcccgg
361 gatatttata agaaccccga ttatgtgaga aaaggagata ctcgacttcc tctgaaatgg
421 atggctcctg aatctatctt tgacaaaatc tacagcacca agagcgacgt gtggtcttac
481 ggagtattgc tgtgggaaat cttctcctta ggtgggtctc catacccagg agtacaaatg
541 gatgaggact tttgcagtcg cctgagggaa ggcatgagga tgagagctcc tgagtactct
601 actcctgaaa tctatcagat catgctggac tgctggcaca gagacccaaa agaaaggcca
661 agatttgcag aacttgtgga aaaactaggt gatttgcttc aagcaaatgt acaacaggat
721 ggtaaagact acatcccaat caatgccata ctgacaggaa atagtgggtt tacatactca
781 actcctgcct tctctgagga cttcttcaag gaaagtattt cagctccgaa gtttaattca
841 ggaagctctg atgatgtcag atatgtaaat gctttcaagt tcatgagcct ggaaagaatc
901 aaaacctttg aagaactttt accgaatgcc acctccatgt ttgatgacta ccagggcgac
961 agcagcactc tgttggcctc tcccatgctg aagcgcttca cctggactga cagcaaaccc
1021 aaggcctcgc tcaagattga cttgagagta accagtaaaa gtaaggagtc ggggctgtct
1081 gatgtcagca ggcccagttt ctgccattcc agctgtgggc acgtcagcga aggcaagcgc
1141 aggttcacct acgaccacgc tgagctggaa aggaaaatcg cgtgctgctc cccgccccca
1201 gactacaact cggtggtcct gtactccacc ccacccatct agagtttgac acgaagcctt
1261 atttctagaa gcaca
//