LOCUS EF491869 1371 bp mRNA linear HUM 27-MAR-2008
DEFINITION Homo sapiens intracellular domain VEGFR1 variant 21 mRNA, complete
cds, alternatively spliced.
ACCESSION EF491869
VERSION EF491869.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1371)
AUTHORS Mezquita,B., Mezquita,J., Pau,M. and Mezquita,C.
TITLE A New Family of Truncated Isoforms of VEGFR1 Consisting of the
Intracellular Domains of the Molecule
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1371)
AUTHORS Mezquita,J.
TITLE Direct Submission
JOURNAL Submitted (13-MAR-2007) Physiology, Faculty of Medicine, University
of Barcelona, Casanova 143, Barcelona 08036, Spain
FEATURES Location/Qualifiers
source 1..1371
/db_xref="H-InvDB:HIT000468818"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="MDA-MB-231"
/PCR_primers="fwd_seq: aagcagtggtatcaacgcagagt, rev_seq:
aagctagtttcctgggggtata"
CDS 307..1338
/note="kinase domain; idVEGFR1p21; alternatively spliced"
/codon_start=1
/product="intracellular domain VEGFR1 variant 21"
/protein_id="ABS32269.1"
/translation="MEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKIC
DFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGG
SPYPGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLG
DLLQANVQQDGKDYIPINAILTGNSGFTYSTPAFSEDFFKESISAPKFNSGSSDDVRY
VNAFKFMSLERIKTFEELLPNATSMFDDYQGDSSTLLASPMLKRFTWTDSKPKASLKI
DLRVTSKSKESGLSDVSRPSFCHSSCGHVSEGKRRFTYDHAELERKIACCSPPPDYNS
VVLYSTPPI"
BASE COUNT 376 a 315 c 317 g 363 t
ORIGIN
1 acagagttac taattttgac agggaactgt accgttttct cccctcaggg attttcatct
61 taatggatca tccccctgcc cccatgcttg gataaagtgg gctggaggcc tggaaaaatc
121 tctggtgttc atgttgaaac tcaaatactc ttaaaaatga actctgatct acttgttggt
181 ttgttttatg ttttgctaac attgttccaa taaactggga tttggtggga taacaagagc
241 cattacaaac agttacggtt ctaatgcttt ccagattctg acggtttcta caaggagccc
301 atcactatgg aagatctgat ttcttacagt tttcaagtgg ccagaggcat ggagttcctg
361 tcttccagaa agtgcattca tcgggacctg gcagcgagaa acattctttt atctgagaac
421 aacgtggtga agatttgtga ttttggcctt gcccgggata tttataagaa ccccgattat
481 gtgagaaaag gagatactcg acttcctctg aaatggatgg ctcctgaatc tatctttgac
541 aaaatctaca gcaccaagag cgacgtgtgg tcttacggag tattgctgtg ggaaatcttc
601 tccttaggtg ggtctccata cccaggagta caaatggatg aggacttttg cagtcgcctg
661 agggaaggca tgaggatgag agctcctgag tactctactc ctgaaatcta tcagatcatg
721 ctggactgct ggcacagaga cccaaaagaa aggccaagat ttgcagaact tgtggaaaaa
781 ctaggtgatt tgcttcaagc aaatgtacaa caggatggta aagactacat cccaatcaat
841 gccatactga caggaaatag tgggtttaca tactcaactc ctgccttctc tgaggacttc
901 ttcaaggaaa gtatttcagc tccgaagttt aattcaggaa gctctgatga tgtcagatat
961 gtaaatgctt tcaagttcat gagcctggaa agaatcaaaa cctttgaaga acttttaccg
1021 aatgccacct ccatgtttga tgactaccag ggcgacagca gcactctgtt ggcctctccc
1081 atgctgaagc gcttcacctg gactgacagc aaacccaagg cctcgctcaa gattgacttg
1141 agagtaacca gtaaaagtaa ggagtcgggg ctgtctgatg tcagcaggcc cagtttctgc
1201 cattccagct gtgggcacgt cagcgaaggc aagcgcaggt tcacctacga ccacgctgag
1261 ctggaaagga aaatcgcgtg ctgctccccg cccccagact acaactcggt ggtcctgtac
1321 tccaccccac ccatctagag tttgacacga agccttattt ctagaagcac a
//