LOCUS EF491868 1579 bp mRNA linear HUM 27-MAR-2008
DEFINITION Homo sapiens intrecellular domain VEGFR1 variant 18 mRNA, complete
cds.
ACCESSION EF491868
VERSION EF491868.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1579)
AUTHORS Mezquita,B., Mezquita,J., Pau,M. and Mezquita,C.
TITLE A New Family of Truncated Isoforms of VEGFR1 Consisting of the
Intracellular Domains of the Molecule
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1579)
AUTHORS Mezquita,J.
TITLE Direct Submission
JOURNAL Submitted (13-MAR-2007) Physiology, Faculty of Medicine, University
of Barcelona, Casanova 143, Barcelona 08036, Spain
FEATURES Location/Qualifiers
source 1..1579
/db_xref="H-InvDB:HIT000468817"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="MDA-MB-231"
/PCR_primers="fwd_seq: aagcagtggtatcaacgcagagt, rev_seq:
aagctagtttcctgggggtata"
CDS 160..1551
/note="kinase domain; idVEGFR1p18"
/codon_start=1
/product="intrecellular domain VEGFR1 variant 18"
/protein_id="ABS32268.1"
/translation="MTELKILTHIGHHLNVVNLLGACTKQGGPLMVIVEYCKYGNLSN
YLKSKRDLFFLNKDAALHMEPKKEKMEPGLEQGKKPRLDSVTSSESFASSGFQEDKSL
SDVEEEEDSDGFYKEPITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNV
VKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIF
SLGGSPYPGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELV
EKLGDLLQANVQQDGKDYIPINAILTGNSGFTYSTPAFSEDFFKESISAPKFNSGSSD
DVRYVNAFKFMSLERIKTFEELLPNATSMFDDYQGDSSTLLASPMLKRFTWTDSKPKA
SLKIDLRVTSKSKESGLSDVSRPSFCHSSCGHVSEGKRRFTYDHAELERKIACCSPPP
DYNSVVLYSTPPI"
BASE COUNT 449 a 373 c 393 g 364 t
ORIGIN
1 gcagaatgtg gggaagttag tgaagcaacc ggctgagcat tgacaaacaa ggagggcaag
61 aatgccgcct ccggcggaag gagccccatt gtcctgtcgc cctgactctt ccttgcttct
121 cacacagagg gggccacggc cagcgagtac aaagctctga tgactgagct aaaaatcttg
181 acccacattg gccaccatct gaacgtggtt aacctgctgg gagcctgcac caagcaagga
241 gggcctctga tggtgattgt tgaatactgc aaatatggaa atctctccaa ctacctcaag
301 agcaaacgtg acttattttt tctcaacaag gatgcagcac tacacatgga gcctaagaaa
361 gaaaaaatgg agccaggcct ggaacaaggc aagaaaccaa gactagatag cgtcaccagc
421 agcgaaagct ttgcgagctc cggctttcag gaagataaaa gtctgagtga tgttgaggaa
481 gaggaggatt ctgacggttt ctacaaggag cccatcacta tggaagatct gatttcttac
541 agttttcaag tggccagagg catggagttc ctgtcttcca gaaagtgcat tcatcgggac
601 ctggcagcga gaaacattct tttatctgag aacaacgtgg tgaagatttg tgattttggc
661 cttgcccggg atatttataa gaaccccgat tatgtgagaa aaggagatac tcgacttcct
721 ctgaaatgga tggctcctga atctatcttt gacaaaatct acagcaccaa gagcgacgtg
781 tggtcttacg gagtattgct gtgggaaatc ttctccttag gtgggtctcc atacccagga
841 gtacaaatgg atgaggactt ttgcagtcgc ctgagggaag gcatgaggat gagagctcct
901 gagtactcta ctcctgaaat ctatcagatc atgctggact gctggcacag agacccaaaa
961 gaaaggccaa gatttgcaga acttgtggaa aaactaggtg atttgcttca agcaaatgta
1021 caacaggatg gtaaagacta catcccaatc aatgccatac tgacaggaaa tagtgggttt
1081 acatactcaa ctcctgcctt ctctgaggac ttcttcaagg aaagtatttc agctccgaag
1141 tttaattcag gaagctctga tgatgtcaga tatgtaaatg ctttcaagtt catgagcctg
1201 gaaagaatca aaacctttga agaactttta ccgaatgcca cctccatgtt tgatgactac
1261 cagggcgaca gcagcactct gttggcctct cccatgctga agcgcttcac ctggactgac
1321 agcaaaccca aggcctcgct caagattgac ttgagagtaa ccagtaaaag taaggagtcg
1381 gggctgtctg atgtcagcag gcccagtttc tgccattcca gctgtgggca cgtcagcgaa
1441 ggcaagcgca ggttcaccta cgaccacgct gagctggaaa ggaaaatcgc gtgctgctcc
1501 ccgcccccag actacaactc ggtggtcctg tactccaccc cacccatcta gagtttgaca
1561 cgaagcctat ttctagaag
//