LOCUS EF219159 1581 bp mRNA linear HUM 16-JAN-2008
DEFINITION Homo sapiens TAK1-like protein 1 (HC21ORF7) mRNA, complete cds,
alternatively spliced.
ACCESSION EF219159
VERSION EF219159.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1581)
AUTHORS Ellis,C.D., Tomlinson,V., Ross,K., Parker,L., Dower,S.K. and
Guesdon,F.
TITLE Regulation of the TGF-beta-activated kinase function by alternative
splicing of its mRNA and by TAK1-like (TAKL) proteins
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1581)
AUTHORS Ellis,C.D. and Guesdon,F.
TITLE Direct Submission
JOURNAL Submitted (19-DEC-2006) School of Medicine and Biomedical Sciences,
University of Sheffield, Beech Hill Road, Sheffield S10 2RX, UK
FEATURES Location/Qualifiers
source 1..1581
/db_xref="H-InvDB:HIT000468760"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="21"
/map="21q22.1"
/clone="IMAGE:4244723"
gene 1..1581
/gene="HC21ORF7"
CDS 130..558
/gene="HC21ORF7"
/function="TAB2- and TAB3-binding protein"
/function="inhibitor of JNK activation"
/note="alternatively spliced; from mRNA variant form J;
TAKL-1"
/codon_start=1
/product="TAK1-like protein 1"
/protein_id="ABN09905.1"
/translation="MISTARVPADKPVRIAFSLNDASDDTPPEDSIPLVFPELDQQLQ
PLPPCHDSEESMEVFKQHCQIAEEYHEVKKEITLLEQRKKELIAKLDQAEKEKVDAAE
LVREFEALTEENRTLRLAQSQCVEQLEKLRIQYQKRQGSS"
polyA_site 1552
/gene="HC21ORF7"
BASE COUNT 497 a 300 c 327 g 457 t
ORIGIN
1 gatcagcagc aacttaacca aagctctgtt acagcctgta gccaagagaa ggaacctgtg
61 gttcgtttcc ccagacggtg tgatgaaaag ctggaagacc caggagaagg cggaggctca
121 ggtgcccaca tgatcagcac agccagggta cctgctgaca agcctgtacg catcgccttt
181 agcctcaatg acgcctcaga tgatacaccc cctgaagact ccattccttt ggtctttcca
241 gaattagacc agcagctaca gcccctgccg ccttgtcatg actccgagga atccatggag
301 gtgttcaaac agcactgcca aatagcagaa gaataccatg aggtcaaaaa ggaaatcacc
361 ctgcttgagc aaaggaagaa ggagctcatt gccaagttag atcaggcaga aaaggagaag
421 gtggatgctg ctgagctggt tcgggaattc gaggctctga cggaggagaa tcggacgttg
481 aggttggccc agtctcaatg tgtggaacaa ctggagaaac ttcgaataca gtatcagaag
541 aggcagggct cgtcctaact ttaaattttt cagtgtgagc atacgaggct gatgactgcc
601 ctgtgctggc caaaagattt ttattttaaa tgaatagtga gtcagatcta ttgcttctct
661 gtattaccca catgacaact gtctataatg agtttactgc ttgccagctt ctagcttgag
721 agaagggata ttttaaatga gatcattaac gtgaaactat tactagtata tgtttttgga
781 gatcagaatt cttttccaaa gatatatgtt tttttctttt ttaggaagat atgatcatgc
841 tgtacaacag ggtagaaaat gataaaaata gactattgac tgacccagct aagaatcgtg
901 ggctgagcag agttaaacca tgggacaaac ccataacatg ttcaccatag tttcacgtat
961 gtgtattttt aaatttcatg cctttaatat ttcaaatatg ctcaaattta aactgtcaga
1021 aacttctgtg catgtattta tatttgccag agtataaact tttatactct gatttttatc
1081 cttcaatgat tgattatact aagaataaat ggtcacatat cctaaaagct tcttcatgaa
1141 attattagca gaaaccatgt ttgtaaccaa agcacatttg ccaatgctaa ctggctgttg
1201 taataataaa cagataaggc tgcatttgct tcatgccatg tgacctcaca gtaaacatct
1261 ctgcctttgc ctgtgtgtgt tctgggggag gggggacatg gaaaaatatt gtttggacat
1321 tacttgggtg agtgcccatg aaaacatcag tgaacttgta actattgttt tgttttggat
1381 ttaaggagat gttttagatc agtaacagct aataggaata tgcgagtaaa ttcagaattg
1441 aaacaatttc tccttgttct acctatcacc acattttctc aaattgaact ctttgttata
1501 tgtccatttc tattcatgta acttcttttt cattaaacat ggatcaaaac caaaaaaaaa
1561 aaaaaaaaaa aaaaaaaaaa a
//