LOCUS EF199840 3382 bp mRNA linear HUM 29-JAN-2007
DEFINITION Homo sapiens erasin (UBXD2) mRNA, complete cds.
ACCESSION EF199840
VERSION EF199840.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3382)
AUTHORS Liang,J., Yin,C., Doong,H., Fang,S., Peterhoff,C., Nixon,R.A. and
Monteiro,M.J.
TITLE Characterization of erasin (UBXD2): a new ER protein that promotes
ER-associated protein degradation
JOURNAL J. Cell. Sci. 119 (PT 19), 4011-4024 (2006)
PUBMED 16968747
REFERENCE 2 (bases 1 to 3382)
AUTHORS Liang,J. and Monteiro,M.J.
TITLE Direct Submission
JOURNAL Submitted (27-DEC-2006) MBC, UMBI, 725 West Lombard Street,
Baltimore, MD 21201, USA
FEATURES Location/Qualifiers
source 1..3382
/db_xref="H-InvDB:HIT000395343"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q21.3"
gene 1..3382
/gene="UBXD2"
CDS 129..1655
/gene="UBXD2"
/note="ER localized protein; clears ERAD substrates"
/codon_start=1
/product="erasin"
/protein_id="ABM90426.1"
/translation="MLWFQGAIPAAIATAKRSGAVFVVFVAGDDEQSTQMAASWEDDK
VTEASSNSFVAIKIDTKSEACLQFSQIYPVVCVPSSFFIGDSGIPLEVIAGSVSADEL
VTRIHKVRQMHLLKSETSVANGSQSESSVSTPSASFEPNNTCENSQSRNAELCEIPPT
SDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEE
QREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDR
AERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSSFTN
QFPSDAPLEEARQFAAQTVGNTYGNFSLATMFPRREFTKEDYKKKLLDLELAPSASVV
LLPAGRPTASIVHSSSGDIWTLLGTVLYPFLAIWRLISNFLFSNPPPTQTSVRVTSSE
PPNPASSSKSEKREPVRKRVLEKRGDDFKKEGKIYRLRTQDDGEDENNTWNGNSTQQM
"
BASE COUNT 1080 a 625 c 743 g 934 t
ORIGIN
1 agccggaggt gggggccgaa ccagccaagg ttgcgggggc cgcagagccg gacgaagacg
61 gagggcggag ccggcttcgg gactgcggag actacacacc gagcgagcgc ctgggcccga
121 agggagcgat gctgtggttc cagggcgcca ttccggccgc catcgcgacg gccaaaagga
181 gcggcgcggt cttcgtggtg ttcgtggcag gtgatgatga acagtctaca cagatggctg
241 caagttggga agatgataaa gttacagaag catcttcaaa cagttttgtt gctattaaaa
301 tcgataccaa aagtgaagcc tgcctacagt tttcacaaat ctatcctgta gtgtgtgttc
361 catccagttt ctttattgga gacagtggaa ttcccttgga agtaatagca ggaagtgttt
421 ctgcagatga acttgttaca agaattcaca aggtccgaca gatgcatttg ctaaaaagtg
481 aaacatcagt agcaaatggc agtcagtcag aaagttcagt gtctactcca tctgcgtcat
541 ttgaacctaa caacacttgt gaaaactctc agtccagaaa tgcagagctt tgtgagatac
601 cacccacttc tgatacaaag tcagatactg caacaggagg agaaagtgca ggccatgcca
661 cttcctctca ggagcctagt ggatgctcag atcagagacc tgcagaggac ctcaacatcc
721 gagtggaaag actaacaaaa aaacttgaag aaaggagaga agagaaaaga aaagaggaag
781 aacagagaga aattaagaag gaaattgaga ggagaaaaac tggaaaagaa atgttggatt
841 ataaaagaaa acaagaagaa gaattaacaa aaagaatgct ggaggaaaga aacagagaga
901 aagcagaaga tagggcagct cgagaacgta taaaacagca gattgcattg gaccgtgcag
961 agagagctgc tcgttttgca aagacaaagg aagaagtaga ggctgccaaa gctgctgcct
1021 tgctagcaaa acaggcagaa atggaagtca agagggaatc ttatgcaaga gaaagaagca
1081 ctgttgcaag aattcaattc cgtcttcctg atggttcttc ctttacaaat cagttccctt
1141 ctgatgctcc tctagaagag gcaaggcagt ttgctgcaca gactgttggc aacacttacg
1201 gtaatttttc gttagcaacc atgtttccca ggagggaatt taccaaagaa gattataaaa
1261 agaagttact ggatttggaa cttgccccaa gcgcttcggt ggtactgttg ccagcaggaa
1321 gaccaactgc atccattgta cactcttcca gcggagacat ttggaccttg ttgggaacag
1381 tgctttatcc attccttgcc atctggagat taattagcaa tttcttgttt agtaatccgc
1441 ctcccacaca gacttcagtg agagtaacat cgtcagaacc cccaaaccct gcatcatcta
1501 gcaaatcaga aaaaagggaa ccagtgagaa aaagagtgct ggaaaaacgt ggagacgact
1561 ttaaaaagga ggggaaaatt tatagattaa ggactcaaga tgatggtgaa gatgaaaaca
1621 acacttggaa tggaaattcc actcaacaga tgtagtgtga caagtataat atgtgcaata
1681 atcattgttt ctcttatgat ttaattcaac taaaattcta ctggagaagt gggactgctt
1741 tatattttcc aactggtcta taaaatgtct ctttattcct gcttagtggg tgtgggttga
1801 aggtgtttaa ctcagaaaag taaagacagg aaataactct ctgctaggtc cttgcttata
1861 tggcaaccac tgctagaacc ctaaaagaac caaaaatctg ccacagcctg cctccatcag
1921 cttcttattt agtatttcat atgcccatta gccctatgct tcagatgaca cgttttgttt
1981 agagctactt tgctccaaga ctcttaagcc caaagtaact ggtatgtcac tgagtaactt
2041 gactcggtgt cagagcattt taactagcca ctcagatgag aatttatgtt taacttctct
2101 ttttactcat cagctgcaag caaaatcttg tagtttttaa tcttaaacac tgaataaaaa
2161 aactttcccc taaattggaa tgatcttagt tttgctttga gttttgttat ctagcatctt
2221 tttgttgcac agggctctat tgaggtccta tgtctctgat tttttttttc cccagtattg
2281 ccctggagct gtctctggaa agtagctggc gaggttacct taactatcac tgaagaaaga
2341 aatattctga cacactgatg gcatgtgact tgtctcctaa gtcagtgagg catcactttg
2401 tttgcataaa gtatacggtt tgttaaggcc tttgttcttg tgagatgcaa aacagctgct
2461 agtctgcaac ctagttttcc ctctcacctt taactgacgt tttgtcctca ataattacac
2521 aaggacctag agtacctata ggacaaaaag tatagaataa aaatatgcct ttagtcattt
2581 ggtttttctt aaaaagttga gattcttaat ctgacttaca tgttacttta tccgtatgtc
2641 tttgttagtg gagaccgcta aactaatgat gtttgaaaac agttcctctg ttttagattg
2701 gaagatagca ctctagagtg gacatacgga aagactgtga ctttattttg taatgggagg
2761 aagaaatttt ctcagagcaa actttctatt ttttacctgt gaaataacag tgacttttta
2821 aaatggtgac agtgttggca aggaaacagc aacacaggct gcgctgttgg taggagtgaa
2881 aaccagtata attcttctga aaaacattta tcagaaactt aaaatatttc ataccgtttg
2941 gtccagtagc ttcttctaaa tcataaatgc agacaatgtt taggtaaaga catactcatt
3001 aagtgttatt tattttactc aagaactgga aaccaactaa atgccttcta tagaagtaat
3061 ttttgatgag gagaaatggt acaatactaa ttaacaactt ggtttaacat gtttactgag
3121 catctgttaa gtgttggggg aaaaagcagc aggatccaga gctataggta cagtgtgatc
3181 tcagctttgc aaacacattt tctacataga tagtactagg tattaataga tatgtaaaga
3241 aagaaatcac accattaata atggtaagat tggtttatgt gattttagtg gtatttttgg
3301 cacccttata tatgttttcc aaacttccag cagtgatatt atttccataa cttaaaaagt
3361 gagtttgaaa aaaaaaaaaa aa
//