LOCUS EF165335 1423 bp mRNA linear HUM 10-JAN-2007
DEFINITION Homo sapiens tissue-type heart K2P2.1 potassium channel (KCNK2)
mRNA, complete cds.
ACCESSION EF165335
VERSION EF165335.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1423)
AUTHORS Thomas,D., Sullivan,A.N. and Goldstein,S.A.
TITLE Direct Submission
JOURNAL Submitted (06-DEC-2006) Pediatrics and Institute for Molecular
Pediatric Sciences, University of Chicago, 5721 S. Maryland Avenue,
Chicago, IL 60637, USA
FEATURES Location/Qualifiers
source 1..1423
/db_xref="H-InvDB:HIT000395059"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q41"
/tissue_type="heart"
gene 1..1423
/gene="KCNK2"
CDS 68..1348
/gene="KCNK2"
/note="two-pore-domain potassium channel subunit; TREK-1;
TPKC1"
/codon_start=1
/product="K2P2.1 potassium channel"
/protein_id="ABM47414.1"
/translation="MLPSASRERPGYRAGVAAPDLLDPKSAAQNSKPRLSFSTKPTVL
ASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTF
ISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGF
GNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQ
TKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGG
SDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTA
NVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSVNHLTSE
RDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK"
BASE COUNT 375 a 323 c 343 g 382 t
ORIGIN
1 ggcgtgtttg taaaaaaaag cttcaagtcc gtctttttca aaaaacattt tgaatgctgc
61 atgcctcatg cttcccagcg cctcgcggga gagacccggc tatagagcag gagtggcggc
121 acctgacttg ctggatccta aatctgccgc tcagaactcc aaaccgaggc tctcgttttc
181 cacgaaaccc acagtgcttg cttcccgggt ggagagtgac acgaccatta atgttatgaa
241 atggaagacg gtctccacga tattcctggt ggttgtcctc tatctgatca tcggagccac
301 cgtgttcaaa gcattggagc agcctcatga gatttcacag aggaccacca ttgtgatcca
361 gaagcaaaca ttcatatccc aacattcctg tgtcaattcg acggagctgg atgaactcat
421 tcagcaaata gtggcagcaa taaatgcagg gattataccg ttaggaaaca cctccaatca
481 aatcagtcac tgggatttgg gaagttcctt cttctttgct ggcactgtta ttacaaccat
541 aggatttgga aacatctcac cacgcacaga aggcggcaaa atattctgta tcatctatgc
601 cttactggga attcccctct ttggttttct cttggctgga gttggagatc agctaggcac
661 catatttgga aaaggaattg ccaaagtgga agatacgttt attaagtgga atgttagtca
721 gaccaagatt cgcatcatct caacaatcat atttatacta tttggctgtg tactctttgt
781 ggctctgcct gcgatcatat tcaaacacat agaaggctgg agtgccctgg acgccattta
841 ttttgtggtt atcactctaa caactattgg atttggtgac tacgttgcag gtggatccga
901 tattgaatat ctggacttct ataagcctgt cgtgtggttc tggatccttg tagggcttgc
961 ttactttgct gctgtcctga gcatgattgg agattggctc cgagtgatat ctaaaaagac
1021 aaaagaagag gtgggagagt tcagagcaca cgctgctgag tggacagcca acgtcacagc
1081 cgaattcaaa gaaaccagga ggcgactgag tgtggagatt tatgacaagt tccagcgggc
1141 cacctccatc aagcggaagc tctcggcaga actggctgga aaccacaatc aggagctgac
1201 tccttgtagg aggaccctgt cagtgaacca cctgaccagc gagagggatg tcttgcctcc
1261 cttactgaag actgagagta tctatctgaa tggtttgacg ccacactgtg ctggtgaaga
1321 gattgctgtg attgagaaca tcaaatagcc ctctctttaa ataaccttag gcatagccat
1381 aggtgaggac ttctctatgc tctttatgac tgttgctggt agc
//