LOCUS EF165334 1586 bp mRNA linear HUM 02-JUL-2008
DEFINITION Homo sapiens tissue-type brain K2P2.1 potassium channel (KCNK2)
mRNA, complete cds.
ACCESSION EF165334
VERSION EF165334.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1586)
AUTHORS Thomas,D., Plant,L.D., Wilkens,C.M., McCrossan,Z.A. and
Goldstein,S.A.
TITLE Alternative translation initiation in rat brain yields K2P2.1
potassium channels permeable to sodium
JOURNAL Neuron 58 (6), 859-870 (2008)
PUBMED 18579077
REFERENCE 2 (bases 1 to 1586)
AUTHORS Thomas,D., Sullivan,A.N. and Goldstein,S.A.
TITLE Direct Submission
JOURNAL Submitted (06-DEC-2006) Pediatrics and Institute for Molecular
Pediatric Sciences, University of Chicago, 5721 S. Maryland Avenue,
Chicago, IL 60637, USA
FEATURES Location/Qualifiers
source 1..1586
/db_xref="H-InvDB:HIT000395058"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q41"
/tissue_type="brain"
gene 1..1586
/gene="KCNK2"
CDS 103..1383
/gene="KCNK2"
/note="two-pore-domain potassium channel subunit; TREK-1;
TPKC1"
/codon_start=1
/product="K2P2.1 potassium channel"
/protein_id="ABM47413.1"
/translation="MLPSASRERPGYRAGVAAPDLLDPKSAAQNSKPRLSFSTKPTVL
ASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTF
ISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGF
GNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQ
TKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGG
SDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTA
NVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSVNHLTSE
RDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK"
BASE COUNT 424 a 355 c 378 g 429 t
ORIGIN
1 gcgcagcccg tctctgaata agaagtgagt acaatggcgt gtttgtaaaa aaaagcttca
61 agtccgtctt tttcaaaaaa cattttgaat gctgcatgcc tcatgcttcc cagcgcctcg
121 cgggagagac ccggctatag agcaggagtg gcggcacctg acttgctgga tcctaaatct
181 gccgctcaga actccaaacc gaggctctcg ttttccacga aacccacagt gcttgcttcc
241 cgggtggaga gtgacacgac cattaatgtt atgaaatgga agacggtctc cacgatattc
301 ctggtggttg tcctctatct gatcatcgga gccaccgtgt tcaaagcatt ggagcagcct
361 catgagattt cacagaggac caccattgtg atccagaagc aaacattcat atcccaacat
421 tcctgtgtca attcgacgga gctggatgaa ctcattcagc aaatagtggc agcaataaat
481 gcagggatta taccgttagg aaacacctcc aatcaaatca gtcactggga tttgggaagt
541 tccttcttct ttgctggcac tgttattaca accataggat ttggaaacat ctcaccacgc
601 acagaaggcg gcaaaatatt ctgtatcatc tatgccttac tgggaattcc cctctttggt
661 tttctcttgg ctggagttgg agatcagcta ggcaccatat ttggaaaagg aattgccaaa
721 gtggaagata cgtttattaa gtggaatgtt agtcagacca agattcgcat catctcaaca
781 atcatattta tactatttgg ctgtgtactc tttgtggctc tgcctgcgat catattcaaa
841 cacatagaag gctggagtgc cctggacgcc atttattttg tggttatcac tctaacaact
901 attggatttg gtgactacgt tgcaggtgga tccgatattg aatatctgga cttctataag
961 cctgtcgtgt ggttctggat ccttgtaggg cttgcttact ttgctgctgt cctgagcatg
1021 attggagatt ggctccgagt gatatctaaa aagacaaaag aagaggtggg agagttcaga
1081 gcacacgctg ctgagtggac agccaacgtc acagccgaat tcaaagaaac caggaggcga
1141 ctgagtgtgg agatttatga caagttccag cgggccacct ccatcaagcg gaagctctcg
1201 gcagaactgg ctggaaacca caatcaggag ctgactcctt gtaggaggac cctgtcagtg
1261 aaccacctga ccagcgagag ggatgtcttg cctcccttac tgaagactga gagtatctat
1321 ctgaatggtt tgacgccaca ctgtgctggt gaagagattg ctgtgattga gaacatcaaa
1381 tagccctctc tttaaataac cttaggcata gccataggtg aggacttctc tatgctcttt
1441 atgactgttg ctggtagcat tttttaaatt gtgcatgagc tcaaaggggg aacaaaatag
1501 atacacccat catggtcatc tatcatcaag agaatttgga attctgagcc agcactttct
1561 ttctgatgat gcttgttgaa cggtcc
//