LOCUS DQ836394 1865 bp mRNA linear HUM 07-FEB-2007
DEFINITION Homo sapiens idVEGFR-1 (FLT1) mRNA, complete cds.
ACCESSION DQ836394
VERSION DQ836394.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1865)
AUTHORS Mezquita,B., Mezquita,J., Pau,M. and Mezquita,C.
TITLE A new truncated isoform of VEGFR-1, consisting of the intracellular
domains of the molecule, may contribute to the invasive phenotype
of breast cancer cells
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1865)
AUTHORS Mezquita,J.
TITLE Direct Submission
JOURNAL Submitted (05-JUL-2006) Molecular Genetics Research Group,
University of Barcelona, Casanova 143, Barcelona 08036, Spain
FEATURES Location/Qualifiers
source 1..1865
/db_xref="H-InvDB:HIT000393394"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="MDA-MB-231"
/cell_type="mammary carcinoma"
gene 1..1865
/gene="FLT1"
CDS 172..1842
/gene="FLT1"
/note="protein kinase"
/codon_start=1
/product="idVEGFR-1"
/protein_id="ABI53803.1"
/translation="MKRSSSEIKTDYLSIIMDPDEVPLDEQCERLPYDASKWEFARER
LKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTH
IGHHLNVVNLLGACTKQGGPLMVIVEYCKYGNLSNYLKSKRDLFFLNKDAALHMEPKK
EKMEPGLEQGKKPRLDSVTSSESFASSGFQEDKSLSDVEEEEDSDGFYKEPITMEDLI
SYSFQVARGMEFLSSRKCIHRDLAARNIFLSENNVVKICDFGLARDIYKNPDYVRKGD
TRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREG
MRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQANVQQDGKDYIPINA
ILTGNSGFTYSTPAFSEDFFKESISAPKFNSGSSDDVRYVNAFKFMSLERIKTFEELL
PNATSMFDDYQGDSSTLLASPMLKRFTWTDSKPKASLKIDLRVTSKSKESGLSDVSRP
SFCHSSCGHVSEGKRRFTYDHAELERKIACCSPPPDYNSVVLYSTPPI"
BASE COUNT 526 a 423 c 456 g 460 t
ORIGIN
1 actttaagtc ttttcctttt ggtcttggag gaacagtgct cagcttttga tctctgtgat
61 tctgatagag aaggaacctc ggacaagtct aatctggagc tgatcactct aacatgcacc
121 tgtgtggctg cgactctctt ctggctccta ttaaccctct ttatccgaaa aatgaaaagg
181 tcttcttctg aaataaagac tgactaccta tcaattataa tggacccaga tgaagttcct
241 ttggatgagc agtgtgagcg gctcccttat gatgccagca agtgggagtt tgcccgggag
301 agacttaaac tgggcaaatc acttggaaga ggggcttttg gaaaagtggt tcaagcatca
361 gcatttggca ttaagaaatc acctacgtgc cggactgtgg ctgtgaaaat gctgaaagag
421 ggggccacgg ccagcgagta caaagctctg atgactgagc taaaaatctt gacccacatt
481 ggccaccatc tgaacgtggt taacctgctg ggagcctgca ccaagcaagg agggcctctg
541 atggtgattg ttgaatactg caaatatgga aatctctcca actacctcaa gagcaaacgt
601 gacttatttt ttctcaacaa ggatgcagca ctacacatgg agcctaagaa agaaaaaatg
661 gagccaggcc tggaacaagg caagaaacca agactagata gcgtcaccag cagcgaaagc
721 tttgcgagct ccggctttca ggaagataaa agtctgagtg atgttgagga agaggaggat
781 tctgacggtt tctacaagga gcccatcact atggaagatc tgatttctta cagttttcaa
841 gtggccagag gcatggagtt cctgtcttcc agaaagtgca ttcatcggga cctggcagcg
901 agaaacattt ttttatctga gaacaacgtg gtgaagattt gtgattttgg ccttgcccgg
961 gatatttata agaaccccga ttatgtgaga aaaggagata ctcgacttcc tctgaaatgg
1021 atggctcctg aatctatctt tgacaaaatc tacagcacca agagcgacgt gtggtcttac
1081 ggagtattgc tgtgggaaat cttctcctta ggtgggtctc catacccagg agtacaaatg
1141 gatgaggact tttgcagtcg cctgagggaa ggcatgagga tgagagctcc tgagtactct
1201 actcctgaaa tctatcagat catgctggac tgctggcaca gagacccaaa agaaaggcca
1261 agatttgcag aacttgtgga aaaactaggt gatttgcttc aagcaaatgt acaacaggat
1321 ggtaaagact acatcccaat caatgccata ctgacaggaa atagtgggtt tacatactca
1381 actcctgcct tctctgagga cttcttcaag gaaagtattt cagctccgaa gtttaattca
1441 ggaagctctg atgatgtcag atatgtaaat gctttcaagt tcatgagcct ggaaagaatc
1501 aaaacctttg aagaactttt accgaatgcc acctccatgt ttgatgacta ccagggcgac
1561 agcagcactc tgttggcctc tcccatgctg aagcgcttca cctggactga cagcaaaccc
1621 aaggcctcgc tcaagattga cttgagagta accagtaaaa gtaaggagtc ggggctgtct
1681 gatgtcagca ggcccagttt ctgccattcc agctgtgggc acgtcagcga aggcaagcgc
1741 aggttcacct acgaccacgc tgagctggaa aggaaaatcg cgtgctgctc cccgccccca
1801 gactacaact cggtggtcct gtactccacc ccacccatct agagtttgac acgaagcctt
1861 atttc
//