LOCUS DQ533873 5920 bp mRNA linear HUM 17-NOV-2006
DEFINITION Homo sapiens ROBO2 isoform a mRNA, complete cds, alternatively
spliced.
ACCESSION DQ533873
VERSION DQ533873.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5920)
AUTHORS Yue,Y., Grossmann,B., Galetzka,D., Zechner,U. and Haaf,T.
TITLE Isolation and differential expression of two isoforms of the
ROBO2/Robo2 axon guidance receptor gene in humans and mice
JOURNAL Genomics 88 (6), 772-778 (2006)
PUBMED 16829019
REFERENCE 2 (bases 1 to 5920)
AUTHORS Yue,Y., Grossmann,B., Galetzka,D., Zechner,U. and Haaf,T.
TITLE Direct Submission
JOURNAL Submitted (08-MAY-2006) Institute for Human Genetics, Mainz
University School of Medicine, Langenbeckstrasse 1, Bldg.601, Mainz
55131, Germany
FEATURES Location/Qualifiers
source 1..5920
/db_xref="H-InvDB:HIT000392757"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p12.3"
CDS 281..4465
/note="roundabout axon guidance receptor-like 2 isoform a;
alternatively spliced"
/codon_start=1
/product="ROBO2 isoform a"
/protein_id="ABF83430.1"
/translation="MARRHERVTRRMWTWAPGLLMMTVVFWGHQGNGQGQGSRLRQED
FPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLP
SGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVV
AAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYT
CVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKK
DDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVV
RPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDL
TITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGT
ALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATS
SSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTL
PASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSP
MSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQ
GYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDS
ESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCLGN
ETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRRNEVV
ITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQ
RGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPP
VPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVD
LPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWANV
PLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVP
TPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQ
SNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPH
RREGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLD
IGYMGSNSQGQFTGEL"
BASE COUNT 1812 a 1287 c 1399 g 1422 t
ORIGIN
1 gcgctggagg agggaggcgg aaggacagcg ctgcgccacc acccggagga gggagcgcgg
61 tagctgcagg caggggaggg agaggaaaga aaaggaagga cggctcccag acagagagtg
121 ggagaaaccg gggagcagcg ggagcagcag gtccgggggg agctgttccg ctgcgctgcc
181 ctcgttattc acacggacgc tgcggagctt cccagggctg cttccctgtc cccctgggtg
241 gaggctgccg tctaaacctg actccagagt ttaagatgca atggccagaa gacatgaacg
301 tgtcactaga aggatgtgga catgggctcc gggactgttg atgatgactg tggtgttttg
361 gggtcatcag gggaatggac aaggccaagg atcgcgtctt cgccaggagg actttccccc
421 gcggattgtg gagcatcctt ccgatgtcat cgtctctaag ggcgagccca cgactctgaa
481 ctgcaaggcg gagggccggc caacgcccac cattgagtgg tacaaagatg gggagcgagt
541 ggagactgac aaggacgatc cccggtccca caggatgctt ctgcccagcg gatccttatt
601 cttcttgcgc atcgtgcacg ggcgcaggag taaacctgat gaaggaagct acgtttgtgt
661 tgcgaggaac tatcttggtg aagcagtgag tcgaaatgcg tctctggaag tggcattgtt
721 acgagatgac ttccgacaaa accccacaga tgttgtagtg gcagctggag agcctgcaat
781 cctggagtgc cagcctcccc ggggacaccc agaacccacc atctactgga aaaaagacaa
841 agttcgaatt gatgacaagg aagaaagaat aagtatccgt ggtggaaaac tgatgatctc
901 caataccagg aaaagtgatg cagggatgta tacttgtgtt ggtaccaata tggtgggaga
961 aagggacagt gacccagcag agctgactgt ctttgaacga cccacatttc tcaggaggcc
1021 aattaaccag gtggtactgg aggaagaagc tgtagaattt cgttgtcaag tccaaggaga
1081 tcctcaacca actgtgaggt ggaaaaagga tgatgcagac ttgccaagag gaaggtatga
1141 catcaaagac gattacacac taagaattaa aaagaccatg agtacagatg aaggcaccta
1201 tatgtgtatt gctgagaatc gggttggaaa aatggaagcc tctgctacac tcaccgtccg
1261 agctccccca cagtttgtgg ttcggccaag agatcagatt gttgctcaag gtcgaacagt
1321 gacatttccc tgtgaaacta aaggaaaccc acagccagct gttttttggc agaaagaagg
1381 cagccagaac ctacttttcc caaaccaacc ccagcagccc aacagtagat gctcagtgtc
1441 accaactgga gacctcacaa tcaccaacat tcaacgttcc gacgcgggtt actacatctg
1501 ccaggcttta actgtggcag gaagcatttt agcaaaagct caactggagg ttactgatgt
1561 tttgacagat agacctccac ctataattct acaaggccca gccaaccaaa cgctggcagt
1621 ggatggtaca gcgttactga aatgtaaagc cactggtgat cctcttcctg taattagctg
1681 gttaaaggag ggatttactt ttccgggtag agatccaaga gcaacaattc aagagcaagg
1741 cacactgcag attaagaatt tacggatttc tgatactggc acttatactt gtgtggctac
1801 aagttcaagt ggagagactt cctggagtgc agtgctggat gtgacagagt ctggagcaac
1861 aatcagtaaa aactatgatt taagtgacct gccagggcca ccatccaaac cgcaggtcac
1921 tgatgttact aagaacagtg tcaccttgtc ctggcagcca ggtacccctg gaacccttcc
1981 agcaagtgca tatatcattg aggctttcag ccaatcagtg agcaacagct ggcagaccgt
2041 ggcaaaccat gtaaagacca ccctctatac tgtaagagga ctgcggccca atacaatcta
2101 cttattcatg gtcagagcga tcaaccccca aggtctcagt gacccaagtc ccatgtcaga
2161 tcctgtgcgc acacaagata tcagcccacc agcacaagga gtggaccaca ggcaagtgca
2221 gaaagagcta ggagatgtcc ttgtccgtct tcataatcca gttgtgctga ctcccaccac
2281 ggttcaggtc acatggacgg ttgatcgcca accccagttt atccaaggct accgagtgat
2341 gtatcgtcag acttcaggtc tgcaggcgac atcttcgtgg cagaatttag atgccaaagt
2401 cccgactgaa cgaagtgctg tcttagtcaa cctgaaaaag ggggtgactt atgaaattaa
2461 agtacggcca tattttaatg agttccaagg aatggatagt gaatctaaaa cggttcgtac
2521 tactgaagaa gccccaagtg ccccaccaca gtctgtcact gtactgacag ttggaagcta
2581 caatagcaca agtattagtg tttcctggga tcctcctcct ccagatcacc agaatggaat
2641 tatccaagaa tacaagatct ggtgtctagg aaatgaaacg cgattccata tcaacaaaac
2701 tgtggatgca gccattcggt ccgtaataat tggtggatta ttcccaggta ttcaataccg
2761 ggtagaggtt gcagctagta ccagtgcagg ggttggagta aagagtgagc cacagccaat
2821 aataatcggg agacgcaatg aagttgtcat tactgaaaac aataacagca taactgagca
2881 aatcactgat gtggtgaagc aaccagcctt tatagctggt attggtggtg cctgctgggt
2941 aattctgatg ggttttagca tatggttgta ttggcgaaga aagaagagga agggactcag
3001 taattatgct gttacgtttc aaagaggaga tggaggacta atgagcaatg gaagccgtcc
3061 aggtcttctc aatgctggtg atcccagcta tccatggctt gctgattctt ggccagccac
3121 gagcttgcca gtaaataata gcaacagtgg cccaaatgag attggaaatt ttggccgtgg
3181 agatgtgctg ccaccagttc caggccaagg ggataaaaca gcaacgatgc tctcagatgg
3241 agccatttat agtagcattg acttcactac caaaaccagt tacaacagtt ccagccaaat
3301 aacacaggct accccatatg ccacgacaca gatcttgcat tccaacagca tacatgaatt
3361 ggctgtcgat ctgcctgatc cacaatggaa aagctcaatt cagcaaaaaa cagatctgat
3421 gggatttggt tattctctac ctgatcagaa caaaggtaac aatggtggga aaggtggaaa
3481 aaagaagaaa aataaaaact cttctaaacc acagaaaaac aatggatcca cttgggccaa
3541 tgtccctcta cctccccccc cagtccagcc ccttcctggc acggagctgg aacactatgc
3601 agtggaacaa caagaaaatg gctatgacag tgatagctgg tgcccaccat tgccagtaca
3661 aacttactta caccaaggtc tggaagatga actggaagaa gatgatgata gggtcccaac
3721 acctcctgtt cgaggcgtgg cttcttctcc tgctatctcc tttggacagc agtccactgc
3781 aactcttact ccatccccac gggaagagat gcaacccatg ctgcaggctc acctggatga
3841 gttgacaaga gcctatcagt ttgatatagc aaaacaaaca tggcacattc aaagcaataa
3901 tcaacctcca cagcctccag ttccaccgtt aggttatgtg tctggagcct tgatttctga
3961 tttggaaacg gatgttgcag atgatgatgc cgacgacgaa gaggaagctt tagaaatccc
4021 caggcccctg agagcactgg accagactcc tggatccagc atggacaatc tagacagctc
4081 tgtgacagga aaagccttta cctcctctca aagacctcga cctaccagcc cattttctac
4141 tgacagtaac accagtgcag ccctgagtca aagtcagagg cctcggccca ctaaaaaaca
4201 caagggaggg cggatggacc aacaaccagc attgcctcat cgaagggaag gaatgacaga
4261 tgaggaggcc ttggtgccct atagcaagcc cagtttccca tctccaggtg gccacagctc
4321 atcaggaaca gcttcttcta agggatccac tggacctagg aaaaccgagg tgttgagagc
4381 aggccaccag cgcaatgcca gcgaccttct tgacatagga tatatgggct ccaacagtca
4441 aggacagttt acaggtgaat tatagtaaat gagaggagac atacaaagct gctctgaagg
4501 accatcaggt ccggactcat ggaagtgatg actctaaaca gtgcaatgaa caatttattt
4561 atgtactatt aaaagaactg taaatgcaat gtaaagacac acagccacac atatcccaca
4621 gatattttca ttgtgttctt ctcttaagta caccacccac cttaactctt tcttgtcagg
4681 agtatataaa aaagaaagaa aacaaaactc gccctacagg aagaaaagga ttctcctctg
4741 tatataattt cttttgtgca ttgctatgca agctcactct ttttagctct gctcatatta
4801 ttgtctgttc ttattggtct gttgtactat atgtgaatta ataggctgtg gtgccatata
4861 ttaactttta attgtgtaac ttttatgttt aaattttgca ctgcaatttt atttggtgat
4921 aagcacaaat ctctactcct catgacatga agaaaaagac tgaatgtgaa gggagtttct
4981 gtactgtaag ctagattgga taatgatggc tgtaacaaat catgttagat ggttttcagt
5041 tggggtgtag aaataggaag atgcaaagga acaatggtgt tggcaaagtc ttctttgaat
5101 atcagggact gagtcaataa aaaaaatagt agaaaggtgg cttttactat tgacaaaagc
5161 cggggtcaaa aaaagtagtt taagtcttaa gactgaatat gcattaaagt atgcaggtag
5221 caaagatgta ataaatttgc ttaaaaaaag aaattaaagt tttatttaga atcaatttta
5281 cctgtcattg taattgaccc atctgagaat tacaataagc aagaggaaat taaggtgttt
5341 tgcaagagct gtatttatat tacagttttt taaaaacatt ttctgaatta tcgtaattaa
5401 gctctccaac tcgttaagtc agaatataat atgaagttcc ccaaggaaac gaacaaaatg
5461 aactctagaa tatctagcaa atagttaaag aagcaattta ttattagggc atactcgggc
5521 tgtttccaaa tataaactct attgcaatat cttatttcat ctttctaata catgtacagt
5581 gcacactaga ggatagagct gcatcactta aattcatgac ttaaaaaata atacagttta
5641 tatacaactt gttttttatt tgattaagaa gtgaagttta cgccacccaa tgtatagcca
5701 aattgtacgt gcttaaaaaa cagtgccgag agtatgttca gttcgcagta agtagattta
5761 ttggaataaa tattctatgg tacattctca gaaattggct tccaactaaa atacgtttga
5821 cccattttga ataaggaaat tgaaaagaaa aatttaaaag gagaaaaaaa tgcatgttta
5881 taaacttttt aaataaaacc agaccttgta agtggacatt
//