LOCUS DQ453796 2305 bp mRNA linear HUM 12-APR-2006
DEFINITION Homo sapiens MYC induced nuclear antigen (MINA) mRNA, complete cds.
ACCESSION DQ453796
VERSION DQ453796.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2305)
AUTHORS Zhang,Y., Lu,Y., Yuan,B.Z., Castranova,V., Shi,X., Stauffer,J.L.,
Demers,L.M. and Chen,F.
TITLE The Human mineral dust-induced gene, mdig, is a cell growth
regulating gene associated with lung cancer
JOURNAL Oncogene 24 (31), 4873-4882 (2005)
PUBMED 15897898
REFERENCE 2 (bases 1 to 2305)
AUTHORS Chang,Q., Castranova,V. and Chen,F.
TITLE MDIG gene, a potential biomarker for human lung cancer
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 2305)
AUTHORS Zhang,Y., Chang,Q. and Chen,F.
TITLE Direct Submission
JOURNAL Submitted (20-MAR-2006) Pathology and Physiology, National
Institute for Occupational Safety and Health, 1095 Willowdale Road,
Morgantown, WV 26505, USA
FEATURES Location/Qualifiers
source 1..2305
/db_xref="H-InvDB:HIT000343385"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3q11.2"
/tissue_type="lung"
gene 1..2305
/gene="MINA"
/gene_synonym="MDIG"
CDS 75..1472
/gene="MINA"
/gene_synonym="MDIG"
/function="contributes to cell growth/proliferation
through direct interaction with PI5K1A and EEF1A proteins"
/note="mineral dust-induced gene; contains alternative
exon 1 compared to mRNA from human lung cancer cell line
deposited in GenBank Accession Number AY302110 or to mRNAs
isolated from human lung cancer tissues"
/codon_start=1
/product="MYC induced nuclear antigen"
/protein_id="ABE28016.1"
/translation="MPKKAKPTGSGKEEGPAPCKQMKLEAAGGPSALNFDSPSSLFES
LISPIKTETFFKEFWEQKPLLIQRDDPALATYYGSLFKLTDLKSLCSRGMYYGRDVNV
CRCVNGKKKVLNKDGKAHFLQLRKDFDQKRATIQFHQPQRFKDELWRIQEKLECYFGS
LVGSNVYITPAGSQGLPPHYDDVEVFILQLEGEKHWRLYHPTVPLAREYSVEAEERIG
RPVHEFMLKPGDLLYFPRGTIHQADTPAGLAHSTHVTISTYQNNSWGDFLLDTISGLV
FDTAKEDVELRTGIPRQLLLQVESTTVATRRLSGFLRTLADRLEGTKELLSSDMKKDF
IMHRLPPYSAGDGAELSTPGGKLPRLDSVVRLQFKDHIVLTVLPDQDQSDEAQEKMVY
IYHSLKNSRETHMMGNEEETEFHGLRFPLSHLDALKQIWNSPAISVKDLKLTTDEEKE
SLVLSLWTECLIQVV"
BASE COUNT 714 a 458 c 540 g 593 t
ORIGIN
1 gtgggctcgc ggccgcgagc aacaggccgt gccgggtttg catttcctta ctgctttgtc
61 ttgaagacag aacgatgcca aagaaagcaa agcctacagg gagtgggaag gaagaggggc
121 cggctccctg taagcagatg aagttagaag cagctggggg gccttcagct ttaaactttg
181 acagtcccag tagtctcttt gaaagtttaa tctcgcccat caagacagag acttttttca
241 aggaattctg ggagcagaag ccccttctca ttcagagaga tgaccctgca ctggccacat
301 actatgggtc cctgttcaag ctaacagatc tgaagagtct gtgcagccgg gggatgtact
361 atggaagaga tgtgaatgtc tgccggtgtg tcaatgggaa gaagaaggtt ttaaataaag
421 atggcaaagc acactttctt cagctgagaa aagattttga tcagaaaagg gcaacgattc
481 agtttcacca acctcagaga tttaaggatg agctttggag gatccaggag aagctggaat
541 gttactttgg ctccttggtt ggctcgaatg tgtacataac tcccgcagga tctcagggcc
601 tgccgcccca ttatgatgat gtcgaggttt tcatcctgca gctggaggga gagaaacact
661 ggcgcctcta ccaccccact gtgcccctgg cacgagagta cagcgtggag gccgaggaaa
721 ggatcggcag gccggtgcat gagtttatgc tgaagccggg tgatttgttg tactttccca
781 gaggaaccat tcatcaagcg gacactcctg cggggctggc ccactctact cacgtgacca
841 tcagcaccta ccagaacaat tcatggggag atttcctttt ggataccatc tcggggcttg
901 tatttgatac tgcaaaggaa gacgtggagt tacggaccgg cataccccgg cagctgctcc
961 tgcaggtgga atccacaact gttgctacaa gacgattaag tggcttcctg aggacacttg
1021 cagaccggct ggagggcacc aaagaactgc tttcctcaga catgaagaag gattttatta
1081 tgcacagact ccccccttac tctgcgggag atggggcaga gctgtcaaca ccaggtggaa
1141 agttaccgag gctggacagt gtagtgagac tgcagtttaa agaccacatt gtcctcacag
1201 tactgccgga tcaagatcaa tctgatgaag ctcaagaaaa gatggtgtac atctatcatt
1261 ccttaaagaa tagtagagag acacacatga tgggaaatga ggaggaaaca gagtttcatg
1321 gacttcgctt ccctttgtca catttggatg cactgaagca aatttggaat agtccagcta
1381 tttctgtcaa ggacctgaaa cttactacag atgaggaaaa ggaaagcctg gtattatccc
1441 tctggacaga atgtttaatt caagtagtct agtgcctttg cagaatcaaa tgcctactat
1501 tttatatgca tatattaaaa gaaaagcaaa gacctgagcc gaggagagga tgaattcaag
1561 tttccttacc tgcgtatcta ctaacaaaca tgagacctcc ctgttacagg tggtcagttg
1621 gccaaatgta ctaacgggca catgaaagaa agaacagcaa attaccaagt gtctcagaaa
1681 atgacaaaac catattttga caagtttatt taatccagtg tggtagaaaa ggcacaattc
1741 caatgtatca tttagaattg aatgtcatta acctggcttt gttctttgga agaaacaact
1801 tctttaaaga gcttctttgg ctctagaaaa atttcaaaca attaaaataa gaaaaaattt
1861 taaactggtt ttttataatg aaaatataca tacctttgtg tatagacaag cccatgccca
1921 ttaaaataaa gttatcctgt aacataaatt ttattaaata atacttcccc acagatgaga
1981 ggcacgcaac acctatggac aaaagggagt tacagaggct gcttaaaaga tggagaaaag
2041 cctgagattg aaggaggaaa aaaacccagt atttaaagtc tataaaaaat actcaaaata
2101 gtgggtcttc gagtttaaaa tagtcattgt tattttacat tctaaagtgc atgtaggttg
2161 atatttttta aaatatcatt ggagaattta atctttcttt ataaaaatag agcatttttc
2221 tgctttctgg caaaagttgg ggataaaagg aaaaaaagtt gtcaaaatgt aattttcagt
2281 ccaattcacc aggaaaacat gcttg
//