LOCUS DQ438905 2324 bp mRNA linear HUM 26-JUL-2016
DEFINITION Homo sapiens GLIS family zinc finger 3 transcript variant TS21
(GLIS3) mRNA, exons 12.1, 17, 18 and partial cds, alternatively
spliced.
ACCESSION DQ438905
VERSION DQ438905.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2324)
AUTHORS Senee,V., Chelala,C., Duchatelet,S., Feng,D., Blanc,H.,
Cossec,J.C., Charon,C., Nicolino,M., Boileau,P., Cavener,D.R.,
Bougneres,P., Taha,D. and Julier,C.
TITLE Mutations in GLIS3 are responsible for a rare syndrome with
neonatal diabetes mellitus and congenital hypothyroidism
JOURNAL Nat. Genet. 38 (6), 682-687 (2006)
PUBMED 16715098
REFERENCE 2 (bases 1 to 2324)
AUTHORS Julier,C.
TITLE Direct Submission
JOURNAL Submitted (09-MAR-2006) INSERM U730, Genetique des Maladies
Infectieuses et Autoimmunes, Institut Pasteur, 28 rue du Docteur
Roux, Paris 75015, France
FEATURES Location/Qualifiers
source 1..2324
/db_xref="H-InvDB:HIT000343365"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9p24.2"
/note="generated by 5' RACE PCR"
gene 1..>2324
/gene="GLIS3"
exon 1..1979
/gene="GLIS3"
/number=12.1
CDS 1928..>2324
/gene="GLIS3"
/note="neonatal diabetes mellitus and congenital
hypothyroidism syndrome; alternatively spliced"
/codon_start=1
/product="GLIS family zinc finger 3 transcript variant
TS21"
/protein_id="ABE66457.1"
/translation="MSHCAWPQIYYLLWKNNWALGFGPQCKSIGKGSCNNLVVTSSPM
MVQRLGLISPPASQVSTACNQISPSLQRAMNAANLNIPPSDTRSLISRESLASTTLSL
TESQSASSMKQEWSQGYRALPSLSNHGSQN"
exon 1980..2187
/gene="GLIS3"
/number=17
exon 2188..>2324
/gene="GLIS3"
/number=18
BASE COUNT 605 a 508 c 477 g 734 t
ORIGIN
1 agagcaggtg ttgtggaaat gctaaaacag aaattttcta attgattaaa atttgaggct
61 aatattattt tttatttaaa tttttaagat tcttatttgt ttatttattt tgagacaggg
121 tctcgctttg tctcccaggc tggagtgcag tagcacgatc atggctcact gcagccttgg
181 tctcctgggc ttaagcaatc ttcctgcctc tgtctcctga gtagccggga ctaccaacat
241 gcctgaataa ttaacaaaat tttttctttt cttttctttc tttctttctt tttttttttt
301 ttttaagaga tggggtctca ctacatttcc caggctgatt tcgaactcct ggtttgaagc
361 aatccttcca ccttagcctt cttaagtgct gggattatag gcatgaacca ccactcccag
421 ccaacattac tttttaaaat ttgactttca taaaagcagt atcctctaga ctgcagtgat
481 taccaatacg gatatggagg tgttgcacac acaatgagta ttgagacagg tgactacctg
541 gtttaccagc tgatttaaat attcttttga agtcatctac atgcctccag aagttaaaaa
601 agaatatatc tgaaacccta acttggctat agaataggtt ggaaagtaca gagttcgtta
661 gaattacatt attatttgta atctgggata aatattgaaa ttgtaataag aaaagtaagt
721 cttacctaaa atacaaggac tttgaagaaa atcacatgat aagacaaaac tgtcaaacaa
781 gcttgggtta acgtggactc atttggttcc agaaaagctc agagtgaaga cagctcgtga
841 attctgtcat caggcagtaa ggcctgtatc gcatgtcact ttgctttgtt tttaatatgt
901 ggttcaagct atgccaggcc tgccgctgtg cgggagatgt actttctgac aaaataaggc
961 attttcctgg catcagatcc ttttggaatt tttactggtt tgcataaacc cggcgagttc
1021 ctatttccca cacatatcca gtgcagtcac acttggcatt gcggatttat ggtggtcttg
1081 aagcctgtca gtgccagcgt ggtcagttcc ttagcaccac tggaggttat tctgaagaaa
1141 tgaaaccagg tattcgttca tccattattt aaaaattgtc tctcacctac tatgcctgta
1201 atgaggaaga aatagcggag gcaaaataga ccaatttcgg aaggactgaa aatattttgt
1261 ggagtggaaa gtatttctag caggctatct ccttttcctc tgtctcctca tcctttatga
1321 taataaagtt cactggaaaa gttcgtttgc attattttgt gttcaaagag ataataatgg
1381 tgatgatgat cacaatgatg atattaatac taacattcat tcttggttgt ctcttactgg
1441 ctgagttgaa atactgtata aataaacaag tctgaggaca tgagtctgag ctcttctgag
1501 ttactttgga aaccctattg gcttgccgtc ttaactcctg gctcttctct cctgaatgta
1561 tttcattgtt ggtcacaaga gagatctgtg gaactatgtg ggccaacccc caagcacaga
1621 tttattatct cttttctttt cttttctttc tttttttttt cttttgaaat ggagtctcac
1681 ttcttcaccc aggctggagt gcactggtgc gatctcggct cactgcaacc tctgcctccc
1741 ggattcaagc aatttccctg cctcagcctc cccagtagct ggaattacag gcatgtgcca
1801 ccatgcccag ttaatttttg tatttttagt agagacgggg tttcaccgtg ttggccaggc
1861 tggtctcaaa ctcctcacct caagtgatcc acctgcctcg ggctcctaaa gtgctgggat
1921 tacagacatg agccactgcg cctggccaca gatttattat ctcttatgga aaaataactg
1981 ggctcttggc tttgggcctc agtgcaagtc cattggaaaa ggcagctgca acaatctagt
2041 ggtcaccagc agtcccatga tggttcagcg actgggactc atttcacctc cagcaagcca
2101 ggtctctaca gcatgcaacc agatcagtcc tagcttacag agggcaatga atgcagccaa
2161 cctgaatata cctccttcag ataccaggtc ccttatttcg cgtgagtctt tggcgtccac
2221 gaccttgagt ctgacggaaa gtcagtcggc ctcaagcatg aagcaggagt ggtcccaggg
2281 ctacagggcc ctcccttcgc tctccaacca cggctctcag aatg
//