LOCUS DQ315361 1811 bp mRNA linear HUM 26-DEC-2005
DEFINITION Homo sapiens metabotropic glutamate receptor 3 splice variant
(GRM3) mRNA, complete cds, alternatively spliced.
ACCESSION DQ315361
VERSION DQ315361.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1811)
AUTHORS Sartorius,L.J., Nagappan,G., Lipska,B.K., Lu,B., Sei,Y.,
Ren-Patterson,R., Li,Z., Weinberger,D.R. and Harrison,P.J.
TITLE Alternative splicing of human metabotropic glutamate receptor 3
JOURNAL J. Neurochem. 96 (4), 1139-1148 (2006)
PUBMED 16417579
REFERENCE 2 (bases 1 to 1811)
AUTHORS Sartorius,L.J., Nagappan,G., Lipska,B.K., Lu,B., Sei,Y.,
Ren-Patterson,R., Li,Z., Weinberger,D.R. and Harrison,P.J.
TITLE Direct Submission
JOURNAL Submitted (02-DEC-2005) GCAP, NIMH, IRP, 10 Center Drive, Bethesda,
MD 20892-4657, USA
FEATURES Location/Qualifiers
source 1..1811
/db_xref="H-InvDB:HIT000342636"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..1811
/gene="GRM3"
CDS 178..1785
/gene="GRM3"
/note="mGluR3; lacks exon 4; alternatively spliced"
/codon_start=1
/product="metabotropic glutamate receptor 3 splice
variant"
/protein_id="ABC47402.1"
/translation="MLTRLQVLTLALFSKGFLLSLGDHNFLRREIKIEGDLVLGGLFP
INEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTY
ALEQSLEFVRASLTKVDEAEYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLR
LFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEG
DYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQKPNARVVVLFMRS
DDSRELIAAASRANASFTWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFDRY
FQSLNPYNNHRNPWFRDFWEQKFQCSLQNKRNHRRVCDKHLAIDSSNYEQESKIMFVV
NAVYAMAHALHKMQRTLCPNTTKLCDAMKILDGKKLYKDYLLKINFTGADDNHVHLCQ
PEWLCGLGLFVCTQGSHHPVSTPEECCHTQTAPQQVQCQWNWDHILSVLCKHVCANGV
QWAGSPRLHHLISVIVNCSSVLVFLDC"
BASE COUNT 445 a 476 c 464 g 426 t
ORIGIN
1 tccagttcct gccaggagtt gtcggtgcga ggaattttgt gacaggctct gttagtctgt
61 tcctccctta tttgaaggac aggccaaaga tccagtttgg aaatgagaga ggactagcat
121 gacacattgg ctccaccatt gatatctccc agaggtacag aaacaggatt catgaagatg
181 ttgacaagac tgcaagttct taccttagct ttgttttcaa agggattttt actctcttta
241 ggggaccata actttctaag gagagagatt aaaatagaag gtgaccttgt tttagggggc
301 ctgtttccta ttaacgaaaa aggcactgga actgaagaat gtgggcgaat caatgaagac
361 cgagggattc aacgcctgga agccatgttg tttgctattg atgaaatcaa caaagatgat
421 tacttgctac caggagtgaa gttgggtgtt cacattttgg atacatgttc aagggatacc
481 tatgcattgg agcaatcact ggagtttgtc agggcatctt tgacaaaagt ggatgaagct
541 gagtatatgt gtcctgatgg atcctatgcc attcaagaaa acatcccact tctcattgca
601 ggggtcattg gtggctctta tagcagtgtt tccatacagg tggcaaacct gctgcggctc
661 ttccagatcc ctcagatcag ctacgcatcc accagcgcca aactcagtga taagtcgcgc
721 tatgattact ttgccaggac cgtgcccccc gacttctacc aggccaaagc catggctgag
781 atcttgcgct tcttcaactg gacctacgtg tccacagtag cctccgaggg tgattacggg
841 gagacaggga tcgaggcctt cgagcaggaa gcccgcctgc gcaacatctg catcgctacg
901 gcggagaagg tgggccgctc caacatccgc aagtcctacg acagcgtgat ccgagaactg
961 ttgcagaagc ccaacgcgcg cgtcgtggtc ctcttcatgc gcagcgacga ctcgcgggag
1021 ctcattgcag ccgccagccg cgccaatgcc tccttcacct gggtggccag cgacggctgg
1081 ggcgcgcagg agagcatcat caagggcagc gagcatgtgg cctacggcgc catcaccctg
1141 gagctggcct cccagcctgt ccgccagttc gaccgctact tccagagcct caacccctac
1201 aacaaccacc gcaacccctg gttccgggac ttctgggagc aaaagtttca gtgcagcctc
1261 cagaacaaac gcaaccacag gcgcgtctgc gacaagcacc tggccatcga cagcagcaac
1321 tacgagcaag agtccaagat catgtttgtg gtgaacgcgg tgtatgccat ggcccacgct
1381 ttgcacaaaa tgcagcgcac cctctgtccc aacactacca agctttgtga tgctatgaag
1441 atcctggatg ggaagaagtt gtacaaggat tacttgctga aaatcaactt cacgggtgca
1501 gacgacaacc atgtgcatct ctgtcagcct gagtggcttt gtggtcttgg gctgtttgtt
1561 tgcacccaag gttcacatca tcctgtttca accccagaag aatgttgtca cacacagact
1621 gcacctcaac aggttcagtg tcagtggaac tgggaccaca tactctcagt cctctgcaag
1681 cacgtatgtg ccaacggtgt gcaatgggcg ggaagtcctc gactccacca cctcatctct
1741 gtgattgtga attgcagttc agttcttgtg tttttagact gttagacaaa agtgctcacg
1801 tgcagctcca g
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