LOCUS DQ310000 1688 bp mRNA linear HUM 27-MAR-2006
DEFINITION Homo sapiens mitochondrial
5-methylaminomethyl-2-thiouridylate-methyltransferase precursor
transcript variant 3 mRNA, complete cds; nuclear gene for
mitochondrial product.
ACCESSION DQ310000
VERSION DQ310000.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1688)
AUTHORS Yan,Q., Bykhovskaya,Y., Li,R., Mengesha,E., Shohat,M., Estivill,X.,
Fischel-Ghodsian,N. and Guan,M.X.
TITLE Human TRMU encoding the mitochondrial
5-methylaminomethyl-2-thiouridylate-methyltransferase is a putative
nuclear modifier gene for the phenotypic expression of the
deafness-associated 12S rRNA mutations
JOURNAL Biochem. Biophys. Res. Commun. 342 (4), 1130-1136 (2006)
PUBMED 16513084
REFERENCE 2 (bases 1 to 1688)
AUTHORS Yan,Q. and Guan,M.X.
TITLE Homo sapiens tRNA 5-methylaminomethyl-2-thiouridylate
methyltransferase (TRMU), nuclear gene encoding mitochondrial
protein, transcript variant 3, mRNA
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 1688)
AUTHORS Yan,Q. and Guan,M.X.
TITLE Direct Submission
JOURNAL Submitted (29-NOV-2005) Human Genetics, Cincinnati Children's
Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio
45229, USA
FEATURES Location/Qualifiers
source 1..1688
/db_xref="H-InvDB:HIT000342629"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="22"
/map="22q13"
CDS 341..640
/note="TRMU; tRNA-methyltransferase"
/codon_start=1
/product="mitochondrial
5-methylaminomethyl-2-thiouridylate-methyltransferase
precursor transcript variant 3"
/protein_id="ABC46692.1"
/translation="MQALRHVVCSLSGGVDSAVAALLLRRRGYQVTGVFMKNWDSLDE
HGVCTADKDCEDAYRVCQILDIPFHQVSYVKEYWNDVFRGRCHCHRSLCKNFPGR"
transit_peptide 341..421
/note="putative mitochondrial target sequence"
BASE COUNT 374 a 425 c 577 g 312 t
ORIGIN
1 ggctgggggg cttagaattt tatttttggt ttacagcgca gaagaagagc agtgaggccg
61 gggcgcgggt ggggagggca aggcggcggc tcaaaaaaaa agccagcccc tcgcggcccg
121 acagagtctc ggcgccccgc gggtcggtgg agcctcaggg gtgagcgcag gccggagaca
181 ggggaacccg ccgcgggaca ggggaaggcc ggacggaacg cgggtaagct gccgcagctt
241 ccggccgggc cactagcgcg gaccctacgg ccggggcggg acttccggca aggcgcggaa
301 gcggcggtag ctgcagctgg cgaagttggg cgactggcgg atgcaggcct tgcggcacgt
361 cgtgtgctcc ctgtccggcg gcgtggacag cgccgtggcc gcgctgctgc tgaggcggag
421 aggttaccag gtgacagggg tgtttatgaa gaactgggac tcactggatg aacatggggt
481 ctgtactgcc gacaaagact gtgaagatgc ttacagagtt tgccagatct tagacatccc
541 tttccatcaa gtgtcctacg taaaggagta ttggaatgat gtgttcaggg gcagatgcca
601 ttgccacagg tcactatgca agaacttccc tggaagatga agaagtcttt gagcagaagc
661 acgttaagaa gcccgaatgg cttttcagaa atcggtttga agttagaaat ggtttcccag
721 gatgccctga ggagaaccat cttccctctg gggggattaa cgaaagagtt tgtaaagaaa
781 atcgctgctg agaatagact tcatcatgtg cttcagaaga aagagagcat gggcatgtgt
841 ttcatcggga agaggaattt tgaacatttc cttcttcagt atctgcagcc tcgacctggt
901 cactttattt ccatagaaga caataaggtt ctgggaacac ataaaggttg gttcctgtat
961 accttgggcc agagagcaaa cataggtggc ctgagagagc cctggtacgt ggtggagaag
1021 gacagcgtca agggtgacgt gtttgtggcc ccccggacag accacccagc cctgtacagg
1081 gacctgctga ggaccagccg cgtgcactgg attgcggagg agcctcccgc agcactggtc
1141 cgggacaaga tgatggagtg ccacttccga ttccgccacc agatggcact agtttgctgt
1201 gttctacaag ggggacgagt gcctgggcag cgggaagatc ctgcggctgg ggccgtctgc
1261 ctacacgctc cagaagggcc agcgcagagc tgggatggcc actgagagcc ccagtgacag
1321 cccagaagat ggtccaggcc tgagtccctt gctctgacag agatggatct gctagaagga
1381 acctggagag caggacccat ggctgggcgg ctggtgagca gtccaggtgc ccaagggcca
1441 gcttgctgct gcccaaagca gaggaagccg ggctggctga gggtccgaaa agcctgcagg
1501 ggcccggcga gccccaggaa gagcctcagc tccaggctgg ggctctggct gctggagcat
1561 ctgctggctg gtggggtggc ccgagttccc cttcaccgcc cccagggagg gtttcccacc
1621 tcagagtaca ccaaggggac ctgcagaggg ggctgtcggg acagcgtgga ataaacatta
1681 tttcaagg
//