LOCUS DQ309999 1830 bp mRNA linear HUM 27-MAR-2006
DEFINITION Homo sapiens mitochondrial
5-methylaminomethyl-2-thiouridylate-methyltransferase precursor
transcript variant 2 mRNA, complete cds; nuclear gene for
mitochondrial product.
ACCESSION DQ309999
VERSION DQ309999.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1830)
AUTHORS Yan,Q., Bykhovskaya,Y., Li,R., Mengesha,E., Shohat,M., Estivill,X.,
Fischel-Ghodsian,N. and Guan,M.X.
TITLE Human TRMU encoding the mitochondrial
5-methylaminomethyl-2-thiouridylate-methyltransferase is a putative
nuclear modifier gene for the phenotypic expression of the
deafness-associated 12S rRNA mutations
JOURNAL Biochem. Biophys. Res. Commun. 342 (4), 1130-1136 (2006)
PUBMED 16513084
REFERENCE 2 (bases 1 to 1830)
AUTHORS Yan,Q. and Guan,M.X.
TITLE Direct Submission
JOURNAL Submitted (29-NOV-2005) Human Genetics, Cincinnati Children's
Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio
45229, USA
FEATURES Location/Qualifiers
source 1..1830
/db_xref="H-InvDB:HIT000342628"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="22"
/map="22q13"
CDS 341..640
/note="TRMU; tRNA-methyltransferase"
/codon_start=1
/product="mitochondrial
5-methylaminomethyl-2-thiouridylate-methyltransferase
precursor transcript variant 2"
/protein_id="ABC46691.1"
/translation="MQALRHVVCALSGGVDSAVAALLLRRRGYQVTGVFMKNWDSLDE
HGVCTADKDCEDAYRVCQILDIPFHQVSYVKEYWNDVFRGRCHCHRSLCKNFPGR"
transit_peptide 341..421
/note="putative mitochondrial target sequence"
BASE COUNT 403 a 468 c 618 g 341 t
ORIGIN
1 ggctgggggg cttagaattt tatttttggt ttacagcgca gaagaagagc agtgaggccg
61 gggcgcgggt ggggagggca aggcggcggc tcaaaaaaaa agccagcccc tcgcggcccg
121 acagagtctc ggcgccccgc gggtcggtgg agcctcaggg gtgagcgcag gccggagaca
181 ggggaacccg ccgcgggaca ggggaaggcc ggacggaacg cgggtaagct gccgcagctt
241 ccggccgggc cactagcgcg gaccctacgg ccggggcggg acttccggca aggcgcggaa
301 gcggcggtag ctgcagctgg cgaagttggg cgactggcgg atgcaggcct tgcggcacgt
361 cgtgtgcgcc ctgtccggcg gcgtggacag cgccgtggcc gcgctgctgc tgaggcggag
421 aggttaccag gtgacagggg tgtttatgaa gaactgggac tcactggatg aacatggggt
481 ctgtactgcc gacaaagact gtgaagatgc ttacagagtt tgccagatct tagacatccc
541 tttccatcaa gtgtcctacg taaaggagta ttggaatgat gtgttcaggg gcagatgcca
601 ttgccacagg tcactatgca agaacttccc tggaagatga agaagtcttt gagcagaagc
661 acgttaagaa gcccgaaggg cttttcagaa atcggtttga agttagaaat gcggtaaaac
721 tcctccaggc agctgacagc tttaaagacc agaccttctt tctcagccag gtttcccagg
781 atgccctgag gagaaccatc ttccctctgg ggggattaac gaaagagttt gtaaagaaaa
841 tcgctgctga gaatagactt catcatgtgc ttcagaagaa agagagcatg ggcatgtgtt
901 tcatcgggaa gaggaatttt gaacatttcc ttcttcagta tctgcagcct cgacctggtc
961 actttatttc catagaagac aataaggttc tgggaacaca taaaggttgg ttcctgtata
1021 ccttgggcca gagagcaaac ataggtggcc tgagagagcc ctggtacgtg gtggagaagg
1081 acagcgtcaa gggtgacgtg tttgtggccc cccggacaga ccacccagcc ctgtacaggg
1141 acctgctgag gaccagccgc gtgcactgga ttgcggagga gcctcccgca gcactggtcc
1201 gggacaagat gatggagtgc cacttccgat tccgccacca gatggcacta gtgccctgtg
1261 tgctgaccct caatcaagat ggcaccgtgt gggtgacagc tgtgcaggct gtgcgtgccc
1321 ttgccacagg acagtttgct gtgttctaca agggggacga gtgcctgggc agcgggaaga
1381 tcctgcggct ggggccgtct gcctacacgc tccagaaggg ccagcgcaga gctgggatgg
1441 ccactgagag ccccagtgac agcccagaag atggtccagg cctgagtccc ttgctctgac
1501 agagatggat ctgctagaag gaacctggag agcaggaccc atggctgggc ggctggtgag
1561 cagtccaggt gcccaagggc cagcttgctg ctgcccaaag cagaggaagc cgggctggct
1621 gagggtccga aaagcctgca ggggcccggc gagccccagg aagagcctca gctccaggct
1681 ggggctctgg ctgctggagc atctgctggc tggtggggtg gcccgagttc cccttcaccg
1741 cccccaggga gggtttccca cctcagagta caccgagggg acctgcagag ggggctgtcg
1801 ggacagcgtg gaataaacat tatttcaagg
//