LOCUS DQ278868 1945 bp mRNA linear HUM 11-JAN-2006
DEFINITION Homo sapiens Tectonic mRNA, complete cds.
ACCESSION DQ278868
VERSION DQ278868.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1945)
AUTHORS Reiter,J.F. and Skarnes,W.C.
TITLE Tectonic, a novel regulator of the Hedgehog pathway required for
both activation and inhibition
JOURNAL Genes Dev. 20 (1), 22-27 (2006)
PUBMED 16357211
REFERENCE 2 (bases 1 to 1945)
AUTHORS Reiter,J.F.
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2005) Developmental and Stem Cell Biology
Program, Univ. Calif., San Francisco, 513 Parnassus, Box 0525, San
Francisco, CA 94143-0525, USA
FEATURES Location/Qualifiers
source 1..1945
/db_xref="H-InvDB:HIT000342575"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q24.11; 109463792-109498888"
CDS 82..1845
/note="extracytosolic protein"
/codon_start=1
/product="Tectonic"
/protein_id="ABB90560.1"
/translation="MRPRGLPPLLVVLLGCWASVSAQTDATPAVTTEGLNSTEAALAT
FGTFPSTRPPGTPRAPGPSSGPRPTPVTDVAVLCVCDLSPAQCDINCCCDPDCSSVDF
SVFSACSVPVVTGDSQFCSQKAVIYSLNFTANPPQRVFELVDQINPSIFCIHITNYKP
ALSFINPEVPDENNFDTLMKTSDGFTLNAESYVSFTTKLDIPTAAKYEYGVPLQTSDS
FLRFPSSLTSSLCTDNNPAAFLVNQAVKCTRKINLEQCEEIEALSMAFYSSPEILRVP
DSRKKVPITVQSIVIQSLNKTLTRREDTDVLQPTLVNAGHFSLCVNVVLEVKYTLTYT
DAGEVTKADLSFVLGTVSSVVVPLQQKFEIHFLQENTQPVPLSGNPGYVVGLPLAAGF
QPHKGSGIIQTTNRYGQLTILHSTTEQDCLALEGVRTPVLFGYTMQSGCKLRLTGALP
CQLVAQKVKSLLWGQGFPDYVAPFGNSQAQDMLDWVPIHFITQSFNRKDSCQLPGALV
IEVKWTKYGSLLNPQAKIVNVTANLISSSFPEANSGNERTILISTAVTFVDVSAPAEA
GFRAPPAINARLPFNFFFPFV"
BASE COUNT 479 a 518 c 440 g 508 t
ORIGIN
1 cgtgatgccc cgcgcctggc tgtcgcggtt gccgggcaac gcgctgtcca tgtcgcgggc
61 ctcgctggga ctccctggga gatgaggccg cgaggtctcc cgccgctcct ggtggtgctc
121 ctgggctgct gggcctccgt gagcgcccag accgatgcca ccccggcggt gacgacagag
181 ggcctcaact ccaccgaggc agccctggcc accttcggaa ctttcccgtc gaccaggccc
241 cccgggactc ccagggctcc agggccctcc tccggcccca ggcctacccc agtcacggac
301 gttgctgttc tctgtgtctg tgacttatcc ccagcacagt gtgacatcaa ctgctgctgt
361 gatcccgact gcagctccgt ggatttcagt gtcttttctg cctgctcagt tccagttgtc
421 acgggcgaca gccagttttg tagtcaaaaa gcagtcatct attcattgaa ttttacagca
481 aacccacctc aaagagtatt tgaacttgtt gaccagatta atccatctat tttctgcatt
541 catattacaa actataaacc tgcattatcc tttattaatc cagaagtacc tgatgaaaac
601 aattttgata cattgatgaa aacatctgat ggttttacat tgaatgctga atcatatgtt
661 tccttcacaa ccaaactgga tattcctact gctgctaaat atgagtatgg ggttcctctg
721 cagacttcag attcgtttct gagatttcct tcgtccctga catcatctct gtgcactgat
781 aataaccctg cagcgtttct ggtgaaccag gctgttaagt gcaccagaaa aataaattta
841 gaacagtgtg aagaaattga agccctcagc atggcttttt acagcagccc ggaaattctg
901 agggtacctg attcaagaaa aaaggtccct atcactgttc agtccatcgt cattcagtct
961 ctaaataaaa cgctcacccg acgggaggac actgatgtgc tgcagccgac tctcgtcaac
1021 gctggacact ttagcctttg cgtgaatgtt gttcttgagg taaagtacac cctcacatac
1081 acagatgcag gtgaagtcac caaagctgat ctctcattcg ttctggggac agttagcagc
1141 gtagtggtcc cactgcagca aaagtttgaa attcattttc ttcaggaaaa tacccagcca
1201 gtccctctca gtggaaaccc tggttatgtc gtggggctcc cattagctgc tggattccag
1261 cctcataagg ggtctgggat tattcagacc acaaatagat atggacagct tactattctt
1321 catagcacaa ctgagcaaga ctgcttagca ctggaggggg tccggacccc agtattattt
1381 ggttacacta tgcaatctgg ctgtaaacta agactgactg gagctctccc atgtcagctc
1441 gtagcacaga aggtgaagag cctgctgtgg ggccagggct tcccagatta cgtggcccct
1501 tttggaaatt cccaggccca ggacatgctg gactgggtgc ccatccactt catcacccag
1561 tcattcaaca ggaaggattc ctgccagctc ccaggggctt tggttataga agtgaagtgg
1621 actaaatacg gatccctgct gaatccacag gccaaaatag tcaatgtaac tgcaaatcta
1681 atttcatcct cctttcctga ggccaactca ggaaatgaaa ggacgattct tatttccact
1741 gcggtaactt ttgtggatgt gtctgcacct gcagaggcag gcttcagagc tccaccagcc
1801 atcaatgcca ggctgccctt taacttcttc ttcccgtttg tttgacaatg ctcagatgca
1861 tcagttcctt aatatacacg tgaaatttga aaactgtaca ttcggtgaga ttaaatttta
1921 tatacaacta gcaaaaaaaa aaaag
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