LOCUS DQ232895 5128 bp mRNA linear HUM 02-DEC-2005
DEFINITION Homo sapiens transferrin receptor trafficking protein mRNA,
complete cds.
ACCESSION DQ232895
VERSION DQ232895.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5128)
AUTHORS Tosoni,D., Puri,C., Confalonieri,S., Salcini,A.E., De Camilli,P.,
Tacchetti,C. and Di Fiore,P.P.
TITLE TTP specifically regulates the internalization of the transferrin
receptor
JOURNAL Cell 123 (5), 875-888 (2005)
PUBMED 16325581
REFERENCE 2 (bases 1 to 5128)
AUTHORS Tosoni,D., Puri,C., Confalonieri,S., Salcini,A.E., De Camilli,P.,
Tacchetti,C. and Di Fiore,P.P.
TITLE Direct Submission
JOURNAL Submitted (06-OCT-2005) IFOM - The FIRC Institute for Molecular
Oncology Foundation, Via Adamello 16, Milano 20139, Italy
FEATURES Location/Qualifiers
source 1..5128
/db_xref="H-InvDB:HIT000342519"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q37.2"
/cell_line="M426"
CDS 368..3259
/note="TTP"
/codon_start=1
/product="transferrin receptor trafficking protein"
/protein_id="ABB18377.1"
/translation="MAAQRIRAANSNGLPRCKSEGTLIDLSEGFSETSFNDIKVPSPS
ALLVDNPTPFGNAKEVIAIKDYCPTNFTTLKFSKGDHLYVLDTSGGEWWYAHNTTEMG
YIPSSYVQPLNYRNSTLSDSGMIDNLPDSPDEVAKELELLGGWTDDKKVPGRTYSNNP
FWNGVQTNPFLNGNVPVMPSLDELNPKSTVDLLLFDTGTSSFTESSSATTNSTGNIFD
ELPVTNGLHAEPPVRRNNPFFRSKRSYSLSELSVLQAKSDAPTSSSFFTGLKSPAPEQ
FQSREDFRTAWLNHRKLARSCHDLDLLGQSPGWGQTQAVETNIVCKLDSSGGAVQLPD
TSISIHVPEGHVAPGETQQISMKALLDPPLELNSDRSCSISPVLEVKLSNLEVKTSII
LEMKVSAEIKNDLFSKSTVGLQCLRSDSKEGPYVSVPLNCSCGDTVQAQLHNLEPCMY
VAVVAHGPSILYPSTVWDFINKKVTVGLYGPKHIHPSFKTVVTIFGHDCAPKTLLVSE
VTRQAPNPAPVALQLWGKHQFVLSRPQDLKVCMFSNMTNYEVKASEQAKVVRGFQLKL
GKVSRLIFPITSQNPNELSDFTLRVQVKDDQEAILTQFCVQTPQPPPKSAIKPSGQRR
FLKKNEVGKIILSPFATTTKYPTFQDRPVSSLKFGKLLKTVVRQNKNHYLLEYKKGDG
IALLSEERVRLRGQLWTKEWYIGYYQGRVGLVHTKNVLVVGRARPSLCSGPELSTSVL
LEQILRPCKFLTYIYASVRTLLMENISSWRSFADALGYVNLPLTFFCRAELDSEPERV
ASVLEKLKEDCNNTENKERKSFQKELVMALLKMDCQGLVVRLIQDFVLLTTAVEVAQR
WRELAEKLAKVSKQQMDAYESPHRDRNGVVDSEAMWKPAYDFLLTWSHQIGDSYRDVI
QELHLGLDKMKNPITKRWKHLTGTLILVNSLDVLRAAAFSPADQDDFVI"
BASE COUNT 1249 a 1408 c 1332 g 1139 t
ORIGIN
1 ggggcccagc gcgcccggca ctctcggcgg tccgggcccc tcgccactac cgccgccgcc
61 gccgccgtga gtcccgcgga gccgcgcgcg cccccggctg ggccgagccg ctggccgacg
121 agcggagcct caggagccgg cggggacgcc atgcgagcca gcgtctccct tctctcctgg
181 acagaaggcc gtgtcctggg acttctctga tggcgagagg ctgcggctgt accaggaaga
241 aacatattgc cgagtggatg ccgccgcgca gcgtgtttgc ttgaggcaga agcttcagca
301 tctgctggga taactggagg aagaaatatg aagccttagc ggctttaccc gggaagcgag
361 tttcgagatg gcggctcagc ggatccgagc ggccaactcc aatggcctcc ctcgctgcaa
421 gtcagagggg accctgattg acctgagcga agggttttca gagacgagct ttaatgacat
481 caaagtgcct tctcccagtg ccttgctcgt agacaacccc acacctttcg gaaatgcaaa
541 ggaagtgatt gcgatcaagg actattgccc caccaacttc accacactga agttctccaa
601 gggcgaccat ctctacgtct tggacacatc tggcggtgag tggtggtacg cacacaacac
661 caccgaaatg ggctacatcc cctcctccta tgtgcagccc ttgaactacc ggaactcaac
721 actgagtgac agcggtatga ttgataatct tccagacagc ccagacgagg tagccaagga
781 gctggagctg ctcgggggat ggacagatga caaaaaagta ccaggcagaa cgtacagtaa
841 taaccctttc tggaatgggg tccagaccaa tccgtttctg aatgggaacg tgcccgtcat
901 gcccagcctg gatgagctga atcccaaaag tactgtggat ttgctccttt ttgacacagg
961 tacatcctcc ttcaccgaat ccagctcagc caccacgaat agcactggca acatcttcga
1021 tgagcttcca gtcacaaacg gactccacgc agagccgccg gtcaggcgga acaacccctt
1081 cttcagaagc aagcgctcct acagtctctc ggaactctcc gtcctccaag ccaagtccga
1141 cgctcccaca tcgtcgagtt tcttcaccgg cttgaaatca cctgcccccg agcaatttca
1201 gagccgggag gattttcgaa ctgcctggct aaaccaccgg aagctggccc ggtcttgcca
1261 cgacctggac ttgcttggcc aaagccctgg ttggggccag acccaagccg tggagacaaa
1321 catcgtgtgc aagctggata gctccggggg tgctgtccag cttcctgaca ccagcatcag
1381 catccacgtg cccgagggcc acgtcgcccc tggggagacc cagcagatct ccatgaaagc
1441 cctgctggac cccccgctgg agctcaacag tgacaggtcc tgcagcatca gccctgtgct
1501 ggaggtcaag ctgagcaacc tggaggtgaa aacctctatc atcttggaga tgaaagtgtc
1561 agccgagata aaaaatgacc tttttagcaa aagcacagtg ggcctccagt gcctgaggag
1621 cgactcgaag gaagggccat atgtctccgt cccgctcaac tgcagctgtg gggacacggt
1681 ccaggcacag ctgcacaacc tggagccctg tatgtacgtg gctgtcgtgg cccatggccc
1741 aagcatcctc tacccttcca ccgtgtggga cttcatcaat aaaaaagtca cagtgggtct
1801 ctacggccct aaacacatcc acccatcctt caagacggta gtgaccattt ttgggcatga
1861 ctgtgcccca aagacgctcc tggtcagcga ggtcacacgc caggcaccca accctgcccc
1921 ggtggccctg cagctgtggg ggaagcacca gttcgttttg tccaggcccc aggatctcaa
1981 ggtctgtatg ttttccaata tgacgaatta cgaggtcaaa gccagcgagc aggccaaagt
2041 ggtgcgagga ttccagctga agctgggcaa ggtgagccgc ctgatcttcc ccatcacctc
2101 ccagaacccc aacgagctct ctgacttcac gctgcgggtt caggtgaagg acgaccagga
2161 ggccatcctc acccagtttt gtgtccagac tcctcagcca ccccctaaaa gtgccatcaa
2221 gccttccggg caaaggaggt ttctcaagaa gaacgaagtc gggaaaatca tcctgtcccc
2281 gtttgccacc actacaaagt acccgacttt ccaggaccgc ccggtgtcca gcctcaagtt
2341 tggtaagttg ctcaagactg tggtgcggca gaacaagaac cactacctgc tggagtacaa
2401 gaagggcgac gggatcgccc tgctcagcga ggagcgggtc aggctccggg gccagctgtg
2461 gaccaaggag tggtacatcg gctactacca gggcagggtg ggcctcgtgc acaccaagaa
2521 cgtgctggtg gtcggcaggg cccggcccag cctgtgctcg ggccccgagc tgagcacctc
2581 ggtgctgctg gagcagatcc tgcggccctg caaattcctc acgtacatct atgcctccgt
2641 gaggaccctg ctcatggaga acatcagcag ctggcgctcc ttcgctgacg ccctgggcta
2701 cgtgaacctg ccgctcacct ttttctgccg ggcagagctg gatagtgagc ccgagcgggt
2761 ggcgtccgtc ctggaaaagc tgaaggagga ctgtaacaac actgagaaca aagaacggaa
2821 gtccttccag aaggagcttg tgatggccct actgaagatg gactgccagg gcctggtggt
2881 cagactcatc caggactttg tgctcctgac cacggctgta gaggtggccc agcgctggcg
2941 ggagctggct gagaagctgg ccaaggtctc caagcagcag atggacgcct acgagtctcc
3001 ccaccgggac aggaacgggg ttgtggacag cgaggccatg tggaagcctg cgtatgactt
3061 cttactcacc tggagccatc agatcgggga cagctaccgg gatgtcatcc aggagctgca
3121 cctgggcctg gacaagatga aaaaccccat caccaagcgc tggaagcacc tcactgggac
3181 tctgatcttg gtgaactccc tggacgttct gagagcagcc gccttcagcc ctgcggacca
3241 ggacgacttc gtgatttgaa tgggtcccct cccctcctgc tgctctggag tgcaagccct
3301 cttctgccct gcgtgccctg ctgtcaccgc ggagctgaag agggaggaag gggcggctgc
3361 tcagacagat ttaggcccgc cagctaggct acacccatca tgcgccgccc tcctccatcg
3421 agggagaggc ctgaagggac tgcctactgc agctcgttgc caatcacata gctttctatt
3481 tgttaagtat aaatttaaat ttaaaatcac ttttttaacg aatgggggga agggatctat
3541 gagaaaggtg gtatctaatt tttttatgga ccataaaggt ttaaaagaaa ataggggcac
3601 aggctgttga ggtttttatg ttgttataga cctttttaaa ttatgttaga gatgtatata
3661 ggtatttaaa ggtcactggg agcgtttctg attcccggcc acactttgca tttcaacact
3721 cagcccggaa agatgctcgt tcggttgttg gacctctttc actccctgcg tgtaagaagg
3781 tgaatcacgt gggaaaaagt ggcttttcag taaacgggta cagctcattc tttctgagaa
3841 ggccccaggt cctgctccct cctcggattt gattgtcttc cgtgctttgc ctcactcgta
3901 gtaaatgacc atccatagaa tatgtgaatc tttggtgagc ttcagtgggc agagtgaagt
3961 cccgcattag catttaggtg ccctgagctg tttctgccaa tagattagaa agcagccatg
4021 agttgacagt ctttagggcc cctgccagtg tgcaattagt cattgacaag aacaatgcca
4081 tttgagagtg aggtggtccc tgctgctacg aggccattgt actgtttttt ccttgaggtc
4141 aaagcagtgc ttcccataga gtttgctgcc tcttctgtgg acaggaagaa aacttcatga
4201 ccgaatcaga gccttggtgg ccactgactc tcgtgcttat tgcagatgct gtggttggcc
4261 tcacaagcaa cgccttatgc tgatgtgcag aggtgccagc tgccatttgc caaactctgc
4321 atttcatttc atctaaggct taacccctct tccttcctgg tgtacctgtg tctcctcgga
4381 aggaagtcat agtttagatg aaaccatttt ttgtacaatg taaagatcat ctgagcaaga
4441 tgagcatttt gtaaaaatga aaatgtgact cacataaaat caggaacttg acacagtgtt
4501 gcattaataa ctttagggtg cagacatgct gtgtgaatct cacaatgcgt cgtagatgtc
4561 gcgtgttgga agggagcagg aggaaggact gatactggca aatcagtaga gtgaggtgat
4621 ccttagcaac gtgccaggac acttcctgtg tgcctgcagt tgtcagggac catttgggat
4681 cccgaatctc attctctaaa actgctttct tgaaacatgt tacttcctta gtataatcaa
4741 tgtatactcc cttactggcc tgaaacgttg tatagctact tattcagata ctgaagacca
4801 acggactgaa aaaaagaaca aacattagct attttatgct gcaagaacca ggacacacaa
4861 ttcgccaatc atcccaccat ataaccttcg attgtgcttc tcaactccac cccataattt
4921 ctcccagaga ccatctatca ccttttcccc aaagaagaaa caaaaccagt tgcaccttaa
4981 accatggata ttttttcctc aggggcttta aatagtttcc tatgcaacgt gtcttgtagc
5041 acaaataaaa ttctacaaaa gttgcagtaa attttatttg gatattttaa aaaaaaaaaa
5101 aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//