LOCUS DQ228004 3948 bp mRNA linear HUM 12-JAN-2006
DEFINITION Homo sapiens TRIOBP isoform 4 (TRIOBP) mRNA, complete cds.
ACCESSION DQ228004
VERSION DQ228004.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3948)
AUTHORS Riazuddin,S., Khan,S.N., Ahmed,Z.M., Ghosh,M., Caution,K.,
Nazli,S., Kabra,M., Zafar,A.U., Chen,K., Naz,S., Antonellis,A.,
Pavan,W.J., Green,E.D., Wilcox,E.R., Friedman,P.L., Morell,R.J.,
Riazuddin,S. and Friedman,T.B.
TITLE Mutations in TRIOBP, Which Encodes a Putative
Cytoskeletal-Organizing Protein, Are Associated with Nonsyndromic
Recessive Deafness
JOURNAL Am. J. Hum. Genet. 78 (1), 137-143 (2006)
PUBMED 16385457
REFERENCE 2 (bases 1 to 3948)
AUTHORS Riazuddin,S., Ahmed,Z.M. and Friedman,T.B.
TITLE Mutations of TARA, encoding a putative cytoskeletal organizing
protein, are associated with nonsyndromic recessive deafness
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 3948)
AUTHORS Riazuddin,S., Ahmed,Z.M. and Friedman,T.B.
TITLE Direct Submission
JOURNAL Submitted (26-SEP-2005) Laboratory of Molecular Genetics, National
Institute For Deafness and Other Communication Disorders, 5
Research Court, Rockville, MD 20850, USA
FEATURES Location/Qualifiers
source 1..3948
/db_xref="H-InvDB:HIT000342506"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="inner ear"
gene 1..3948
/gene="TRIOBP"
CDS 451..3885
/gene="TRIOBP"
/note="F-actin binding protein; TRIOBP-4"
/codon_start=1
/product="TRIOBP isoform 4"
/protein_id="ABB59560.1"
/translation="MIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGR
SAGQHWARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTRE
IPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRA
SSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRA
SSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATR
DNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQ
RDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRT
SSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRD
NPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRD
NPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRT
IQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCA
QRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRT
QSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLR
PTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQY
NLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASS
PPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFP
FLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRAST
ESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPS
TDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGE
TRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERR"
BASE COUNT 946 a 1541 c 869 g 592 t
ORIGIN
1 cccaggggag gaggtgaaat tcctcagctc tccaccaaga ttggccacaa aagcctgatc
61 ccctggaaca cagcaggcct cacatagacg gtcagccatt ggatcatagg aactgccctg
121 gcctgactca cccaatatgg aggaggtgcc tggggatgcc ctgtgtgaac actttgaggc
181 caacatactt acccagaacc gctgtcaaaa ctgcttccac cctgaggagg cccatggagc
241 aagataccag gagctcagga gcccttcagg tgctgaggtg ccctactgcg acctgcctcg
301 atgtccacct gcccctgagg acccactcag cgcctcaacc tccggctgcc agtctgtggt
361 ggacccaggc ctcaggccag ggcccaagag gactgggaca ctgttgagag gcaggaggag
421 gaggccccca gctgggacga gctcgcagtg atgatcccga ggaggcctcg ggaggggccg
481 agagctgaca gctcccaaag ggctccgtct ctcctcacca ggtcccctgt gggaggagat
541 gctgcaggcc agaaaaagga ggacaccggc ggtgggggcc ggagcgcagg acagcactgg
601 gcaaggctcc ggggagaaag cgggttgtcc ctggagcggc accggtcaac actgacccag
661 gcttcctcca tgacaccaca cagtggacct cgaagcacca cgtctcaggc ttctcctgcc
721 caaagggaca ctgctcaggc tgcctctaca cgtgaaatcc ccagagcctc ctctccccat
781 cgaatcaccc aaagggacac ctccagggcc tcatccaccc aacaggaaat ctccagggcc
841 tcatccaccc aacaggaaac ctccagggcc tcatccaccc aagaggacac ccctagggcc
901 tcatccaccc aagaggacac ccccagggcc tcatctacac agtggaacac ccccagagct
961 tcctctccct cacgaagcac ccaactggat aaccccagaa cctcttctac ccagcaggac
1021 aacccccaaa cttcttttcc tacttgtact ccccagcggg aaaaccccag gacaccctgt
1081 gtccagcagg acgatcccag agcctcctct cccaacagaa ccactcaacg agagaattcc
1141 agaacatcct gtgcccagcg ggacaatccc aaagcctcca gaacctcctc tcccaataga
1201 gccacacgag acaaccccag aacatcctgc gcccagcggg acaatcccag agcctcctct
1261 cccagtagag ctacacgaga caaccccaca acatcctgtg cccagcggga caatcccaga
1321 gcctccagaa cctcctctcc caatagagcc acacgagaca accccagaac atcctgtgcc
1381 cagcgggaca atcccagagc ctcctctccc agtagagcta cacgagacaa ccccacaaca
1441 tcctgtgccc agcgggacaa tcccagagcc tccagaacct cctctcccaa tagagccaca
1501 cgagacaacc ccagaacatc ctgcgcccag cgggacaatc ccagagcctc ctctcccaat
1561 agagctgcac gagacaaccc cacaacatcc tgtgcccagc gggacaatcc cagagcctcc
1621 agaacctcct ctcccaatag agccacacga gacaacccca gaacatcctg tgcccagcgg
1681 gacaatccca gagcctcctc tcccaataga gctacacgag acaaccccac aacatcctgt
1741 gcccagcggg acaatcccag agcctccaga acctcctctc ccaatagagc cacacgagat
1801 aaccccagaa catcctgtgc ccagcgggac aatcccagag cctcctctcc caacagaacc
1861 acccaacaag acagccccag aacatcctgt gcccgacggg acgatcccag agcctcctct
1921 cctaacagaa ccatccaaca agagaacccc agaacatcct gtgccctacg ggacaatccc
1981 agagcctcct ctcccagcag aaccatccaa caagagaacc ccagaacatc ctgtgcccaa
2041 cgggacgatc ccagagcctc ctctcctaac agaaccaccc aacaagagaa ccccagaaca
2101 tcctgtgccc gacgggacaa tcccagagcc tcctctcgca acagaaccat ccagcgagac
2161 aaccccagaa catcctgtgc ccagcgggac aatcccagag cctcctctcc taacagaacc
2221 atccaacaag agaacctcag aacatcctgt acccgacagg acaatcccag gacctcctct
2281 cccaatagag ccacacgaga caaccccaga acatcctgtg cccagcggga caatctcaga
2341 gcctcctctc ccatcagagc cacccaacag gacaacccca gaacttgtat tcaacagaac
2401 atccccagat catcttctac ccaacaagac aaccctaaaa cctcttgtac caaacgagat
2461 aacctcagac ccacttgtac acagcgggac cgcacacagt ccttttcctt tcaacgagac
2521 aaccctggaa cctcctcatc tcaatgctgc acccaaaagg agaatctgag accatcatct
2581 ccccaccgct ccactcaatg gaacaatccc aggaattcat ctccccatcg tactaacaaa
2641 gacatcccct gggcctcgtt tcccctccgg ccaactcaga gtgatggtcc ccgaacctct
2701 tccccatctc gctccaagca aagcgaggtt ccctgggcat ccatcgccct ccggccaacc
2761 caaggtgaca ggcctcagac atcctctccc agcaggccag cccagcatga cccaccccag
2821 tcctcctttg gccccaccca gtacaacttg ccatcccggg ccacctcttc ctcccataac
2881 ccaggccacc agagcacctc ccgaacttcc tcacctgtgt accccgctgc ctatggggct
2941 cccctgacct ctcctgagcc ctcccagcct ccatgtgctg tgtgcattgg gcaccgggat
3001 gcccctcgag cctcttcgcc ccctcgctat ttgcagcacg accccttccc cttcttccca
3061 gagccccgcg cccctgagag tgaaccgccc caccacgagc ctccctatat accacctgct
3121 gtgtgcattg gacaccgaga tgccccccgg gcgtcctcgc ccccccgcca cacccaattt
3181 gaccccttcc ccttcctccc agacacatca gatgccgagc atcagtgtca gtccccccaa
3241 cacgagcccc ttcagctccc tgcacctgtg tgtattgggt accgagatgc accccgggcc
3301 tcctccccac cacgccaggc cccagagcct tccctcttat tccaggacct ccccagggcc
3361 agcacagaga gccttgtccc ttccatggac tctctgcacg agtgccccca catccccacc
3421 cctgtgtgca ttgggcaccg ggatgcaccc tccttctcat ccccaccacg ccaggctcct
3481 gagccatccc tcttcttcca ggatccccct ggaactagta tggagagcct ggccccctcc
3541 actgactctc tgcatggctc cccagtgctg atcccccaag tgtgcatcgg gcaccgggat
3601 gcaccccgag cctcctcccc accccgccac ccacccagtg acctagcgtt cctggcaccc
3661 tcaccttcac cgggcagctc tgggggctcc cggggctcag cgcctcccgg ggagaccagg
3721 cacaacttgg agcgggagga gtacactgtg ctggccgacc tgcccccacc caggaggctg
3781 gcccagagac agccagggcc ccaggcgcag tgcagcagcg ggggccgcac ccacagccct
3841 ggccgtgcag aggtggagcg cctcttcggg caagagcgca ggtgagcccg ggggtggggt
3901 cagccaggtg ggctggggag gaggctcggc agcaggacag gtgaaggg
//