LOCUS DQ227317 2564 bp mRNA linear HUM 13-APR-2006
DEFINITION Homo sapiens synphilin-1A (SNCAIP) mRNA, complete cds.
ACCESSION DQ227317
VERSION DQ227317.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2564)
AUTHORS Eyal,A., Szargel,R., Avraham,E., Liani,E., Haskin,J., Rott,R. and
Engelender,S.
TITLE Synphilin-1A: an aggregation-prone isoform of synphilin-1 that
causes neuronal death and is present in aggregates from
alpha-synucleinopathy patients
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 103 (15), 5917-5922 (2006)
PUBMED 16595633
REFERENCE 2 (bases 1 to 2564)
AUTHORS Eyal,A. and Engelender,S.
TITLE Direct Submission
JOURNAL Submitted (29-SEP-2005) Pharmacology, Technion, Faculty of
Medicine, Efron St., Haifa 31096, Israel
FEATURES Location/Qualifiers
source 1..2564
/db_xref="H-InvDB:HIT000342503"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2564
/gene="SNCAIP"
CDS 253..2064
/gene="SNCAIP"
/codon_start=1
/product="synphilin-1A"
/protein_id="ABB51162.1"
/translation="MTYLIQSHHSRRSQNCAEDVIRKTKTDQNGQLECVRWMVSETEA
IAELSCSKDFPSLIHYAGCYGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHG
YLGCIQTLVEYGANVTMQNHAGEKPSQSAERQGHTLCSRYLVVVETCMSLASQVVKLT
KQLKEQTVERVTLQNQLQQFLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDADDDSV
AKSKPGVQEGIQVLGSLSASSRARPKAKDEDSDKILRQLLGKEISENVCTQEKLSLEF
QDAQASSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKTTPVRKADRPR
PQPIVESVESMDSAESLHLMIKKHTLASGGRRFPFSIKASKSLDGHSPSPTSESSEPD
LESQYPGSGSIPPNQPSGDPQQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRV
TFEEPVVQMEQPSLELNGEKDKDKGRTLQRTSTSNESGDQLKRPFGAFRSIMETLSGN
QNNNNNYQAANQLKTSTLPLTSLGRKTDAKGNPASSASKGKNKAEMYSSCINLSSNML
IEEHLCNDTRHNDINRKMKKSYSIKHIAEPESKELFL"
BASE COUNT 765 a 625 c 596 g 578 t
ORIGIN
1 cgcccgcggc cgggccgcat tgtgacgtag cggggccgcg gcagcgcctc caccgcccgc
61 ctacttcggc tgaggctgtt ctgctcctgc cgctgcggtc cgtcggtcgg tcagtcagtc
121 ccttcgcgct cctgagccgc cggcgcgccg ggcgccccgg gaatttataa gtatttgacc
181 gtactcaaaa tgtgcaagga agaataatgg aagcccctga ataccttgat ttggatgaaa
241 ttgactttag tgatgacata tcttattcag tcacatcact caagacgatc ccagaactgt
301 gccgaagatg tgatacgcaa aacgaagaca gatcagaatg gtcagttgga gtgcgtacgc
361 tggatggtga gcgaaacaga agccattgca gaactgagtt gttctaagga ttttccaagc
421 cttattcatt acgcaggttg ctatggccag gaaaagattc ttctgtggct tcttcagttt
481 atgcaagaac agggcatctc gttggatgaa gtagaccagg atggcaacag tgccgttcac
541 gtagcctcac agcatggcta ccttggatgc atacagacct tggttgaata tggagcaaat
601 gtcaccatgc agaaccacgc tggggaaaag ccctcccaga gcgccgagcg gcaggggcac
661 accctgtgct ccaggtacct ggtggtggtg gagacctgca tgtcgctggc ctctcaagtg
721 gtgaagttaa ccaagcagct aaaggaacaa acagtagaac gtgtcacgct gcagaaccaa
781 ctccaacaat ttctagaagc ccagaaatca gagggcaagt cactcccttc ttcacccagt
841 tcaccatcct cacctgcctc cagaaagtcc cagtggaaat ctccagatgc agatgatgat
901 tctgtagcca aaagcaagcc aggagtccaa gaggggattc aggttcttgg aagcctgtca
961 gcctccagcc gggctagacc caaagcaaaa gatgaagatt ctgataaaat cttacgccag
1021 ttattgggaa aggaaatctc agaaaatgtc tgcacccagg aaaaactgtc cttggaattc
1081 caggatgctc aggcttcctc tagaaattct aaaaagatcc cactggagaa gagggaactg
1141 aagttagcca ggctgagaca gctgatgcag aggtcactga gtgagtctga cacagactcc
1201 aacaactctg aggaccccaa gactacccca gtgaggaagg ctgaccgacc aaggccgcag
1261 cccattgtag aaagcgtaga gagtatggac agcgcagaaa gcctgcacct gatgattaag
1321 aaacacacct tggcatcagg gggacgcagg tttcctttca gcatcaaggc ctccaaatcc
1381 ctggatggcc acagcccatc tcccacctca gagagcagcg aaccagactt agaatcccag
1441 tatccaggct cagggagtat tcctccaaac cagccctctg gtgaccctca gcagcccagc
1501 cctgacagta ctgctgccca gaaagttgcc acaagtccca agagtgccct caagtctcca
1561 tcttccaagc gtaggacatc tcagaactta aaactgagag ttacctttga ggagcctgtg
1621 gtgcagatgg agcagcctag ccttgaactg aatggagaaa aagacaaaga taagggcagg
1681 actctccagc ggacctccac aagtaacgaa tcgggggatc aactgaaaag gccttttgga
1741 gcctttcgat ctatcatgga gacactaagt ggcaaccaaa acaataataa taactaccag
1801 gcagccaacc agctgaaaac ctctacattg cccttgacct cacttgggag gaagacagat
1861 gccaagggaa accctgccag ctccgctagc aaaggaaaga ataaggcaga aatgtacagc
1921 agctgcatca atctttcctc taacatgctg attgaagagc atctgtgtaa cgacacacgg
1981 cataatgaca tcaatagaaa aatgaagaaa tcctacagca taaagcacat tgctgagcca
2041 gagtcaaaag aactcttctt gtaaatcact ttttaaattt tctctcactg atgccctttg
2101 gaaattattg gaaatttctg gactatcctc tttggaaaga gaaccatgaa aacaatgcct
2161 caccagcaga agaacagaat atcaggatgc cttaaattta tagtagtaga ctgtaaaaga
2221 ttcattttgg ggtgatatct gtatatataa cttgtttttt taaaagatgc cgtttaaaag
2281 catgattggg aaaatgtacg ttttttaaga gtagattgat tcaccctacc cacaggacat
2341 tcaccaagcc actgatacca ttttatattt catcaattgc atgagtattt gctaatgttg
2401 attgaacctc cctttcccca taatgtgggc agatttggct cagctccttc atgagatcag
2461 gtcagtggta ttgtttctgt caagagtgtt ttttctgtca tttctacttt ttgtataaag
2521 gaaataaaac aatgttaaca gccaaaaaaa aaaaaaaaaa aaaa
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