LOCUS DQ180742 1893 bp mRNA linear HUM 09-OCT-2005
DEFINITION Homo sapiens cyclooxygenase 1b3 mRNA, complete cds, alternatively
spliced.
ACCESSION DQ180742
VERSION DQ180742.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1893)
AUTHORS Qin,N., Zhang,S.P., Reitz,T.L., Mei,J.M. and Flores,C.M.
TITLE Cloning, Expression and Functional Characterization of Human COX-1
Splicing Variants: Evidence for Intron 1 Retention
JOURNAL J. Pharmacol. Exp. Ther. (2005) In press
PUBMED 16141368
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 1893)
AUTHORS Qin,N.
TITLE Direct Submission
JOURNAL Submitted (25-AUG-2005) Drug Discovery, Johnson & Johnson
Pharmaceutical Research and Development. L.L.C., Welsh and McKean
Roads, Spring House, PA 19477, USA
FEATURES Location/Qualifiers
source 1..1893
/db_xref="H-InvDB:HIT000342111"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
CDS 1..1893
/note="COX-1b3; alternatively spliced"
/codon_start=1
/product="cyclooxygenase 1b3"
/protein_id="ABA60099.1"
/translation="MSRECDPGARWGIFLASGGALNARLSPSSLSSAGSLLLWFLLFL
LLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIP
GLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTY
NSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFI
PDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRL
FKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATL
WLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFD
PELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVE
ALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSF
QELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLG
NPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVE
RPSTEL"
BASE COUNT 372 a 577 c 506 g 438 t
ORIGIN
1 atgagccgtg agtgcgaccc cggtgcccgg tggggaattt tcttggcctc tggtggagcc
61 ttgaatgcca ggctcagccc ctcatctctc tcctctgcag ggagtctctt gctctggttc
121 ttgctgttcc tgctcctgct cccgccgctc cccgtcctgc tcgcggaccc aggggcgccc
181 acgccagtga atccctgttg ttactatcca tgccagcacc agggcatctg tgtccgcttc
241 ggccttgacc gctaccagtg tgactgcacc cgcacgggct attccggccc caactgcacc
301 atccctggcc tgtggacctg gctccggaat tcactgcggc ccagcccctc tttcacccac
361 ttcctgctca ctcacgggcg ctggttctgg gagtttgtca atgccacctt catccgagag
421 atgctcatgc gcctggtact cacagtgcgc tccaacctta tccccagtcc ccccacctac
481 aactcagcac atgactacat cagctgggag tctttctcca acgtgagcta ttacactcgt
541 attctgccct ctgtgcctaa agattgcccc acacccatgg gaaccaaagg gaagaagcag
601 ttgccagatg cccagctcct ggcccgccgc ttcctgctca ggaggaagtt catacctgac
661 ccccaaggca ccaacctcat gtttgccttc tttgcacaac acttcaccca ccagttcttc
721 aaaacttctg gcaagatggg tcctggcttc accaaggcct tgggccatgg ggtagacctc
781 ggccacattt atggagacaa tctggagcgt cagtatcaac tgcggctctt taaggatggg
841 aaactcaagt accaggtgct ggatggagaa atgtacccgc cctcggtaga agaggcgcct
901 gtgttgatgc actacccccg aggcatcccg ccccagagcc agatggctgt gggccaggag
961 gtgtttgggc tgcttcctgg gctcatgctg tatgccacgc tctggctacg tgagcacaac
1021 cgtgtgtgtg acctgctgaa ggctgagcac cccacctggg gcgatgagca gcttttccag
1081 acgacccgcc tcatcctcat aggggagacc atcaagattg tcatcgagga gtacgtgcag
1141 cagctgagtg gctatttcct gcagctgaaa tttgacccag agctgctgtt cggtgtccag
1201 ttccaatacc gcaaccgcat tgccatggag ttcaaccatc tctaccactg gcaccccctc
1261 atgcctgact ccttcaaggt gggctcccag gagtacagct acgagcagtt cttgttcaac
1321 acctccatgt tggtggacta tggggttgag gccctggtgg atgccttctc tcgccagatt
1381 gctggccgga tcggtggggg caggaacatg gaccaccaca tcctgcatgt ggctgtggat
1441 gtcatcaggg agtctcggga gatgcggctg cagcccttca atgagtaccg caagaggttt
1501 ggcatgaaac cctacacctc cttccaggag ctcgtaggag agaaggagat ggcagcagag
1561 ttggaggaat tgtatggaga cattgatgcg ttggagttct accctggact gcttcttgaa
1621 aagtgccatc caaactctat ctttggggag agtatgatag agattggggc tcccttttcc
1681 ctcaagggtc tcctagggaa tcccatctgt tctccggagt actggaagcc gagcacattt
1741 ggcggcgagg tgggctttaa cattgtcaag acggccacac tgaagaagct ggtctgcctc
1801 aacaccaaga cctgtcccta cgtttccttc cgtgtgccgg atgccagtca ggatgatggg
1861 cctgctgtgg agcgaccatc cacagagctc tga
//