LOCUS DQ145719 3626 bp mRNA linear HUM 18-OCT-2006
DEFINITION Homo sapiens folliculin-interacting protein 1 (FNIP1) mRNA,
complete cds.
ACCESSION DQ145719
VERSION DQ145719.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3626)
AUTHORS Baba,M., Hong,S.B., Sharma,N., Warren,M.B., Nickerson,M.L.,
Iwamatsu,A., Esposito,D., Gillette,W.K., Hopkins,R.F. III,
Hartley,J.L., Furihata,M., Oishi,S., Zhen,W., Burke,T.R. Jr.,
Linehan,W.M., Schmidt,L.S. and Zbar,B.
TITLE Folliculin encoded by the BHD gene interacts with a binding
protein, FNIP1, and AMPK, and is involved in AMPK and mTOR
signaling
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 103 (42), 15552-15557 (2006)
PUBMED 17028174
REFERENCE 2 (bases 1 to 3626)
AUTHORS Baba,M., Nickerson,M.L., Hong,S.-B., Sharma,N., Warren,M.B.,
Schmidt,L.S. and Zbar,B.
TITLE Direct Submission
JOURNAL Submitted (26-JUL-2005) Laboratory of Immunobiology, National
Cancer Institute-Frederick, Bldg 560 Room 12-69, Frederick, MD
21702, USA
FEATURES Location/Qualifiers
source 1..3626
/db_xref="H-InvDB:HIT000391743"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q23.3"
gene 1..3626
/gene="FNIP1"
CDS 48..3548
/gene="FNIP1"
/codon_start=1
/product="folliculin-interacting protein 1"
/protein_id="AAZ65854.1"
/translation="MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRL
IVYQDCERRGRNVLFDSSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDS
SVTSSSDIKDQCLKYQGSRCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLS
KVFTARTGSSICGSLNTLQDSLEFINQDNNTLKADNNTVINGLLGNIGLSQFCSPRRA
FSEQGPLRLIRSASFFAVHSNPMDMPGRELNEDRDSGIARSASLSSLLITPFPSPNSS
LTRSCASSYQRRWRRSQTTSLENGVFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGV
IFSLSKDEDENNKFNEFFFSHFPLFESHMNKLKSAIEQAMKMSRRSADASQRSLAYNR
IVDALNEFRTTICNLYTMPRIGEPVWLTMMSGTPEKNHLCYRFMKEFTFLMENASKNQ
FLPALITAVLTNHLAWVPTVMPNGQPPIKIFLEKHSSQSVDMLAKTHPYNPLWAQLGD
LYGAIGSPVRLARTVVVGKRQDMVQRLLYFLTYFIRCSELQETHLLENGEDEAIVMPG
TVITTTLEKGEIEESEYVLVTMHRNKSSLLFKESEEIRTPNCNCKYCSHPLLGQNVEN
ISQQEREDIQNSSKELLGISDECRMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVV
CTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIVPA
SFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHHTKPLKEERGAIDQHQETK
QTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFNDDSIETRTIDDVPFKT
STDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTCFPQQDQRDTLSILVP
HGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVSSYYGGEQEDWAE
EDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSDERFRQCLMSD
LSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVSSLVSNLLH
STLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVLGIESSD
LPLLAAVASTHSPYVAQILL"
BASE COUNT 1115 a 733 c 827 g 951 t
ORIGIN
1 gcctagcaag cgcccagcgg agcgacccct gcctggccgt ggctagcatg gcccctacgc
61 tgttccagaa gctcttcagc aagaggaccg ggctgggcgc gcccggccgc gacgcccggg
121 acccagattg cgggttcagt tggcctttac cagagtttga tccaagccag attcgactga
181 ttgtatatca agactgtgaa agacgaggga gaaatgtttt gtttgactcc agtgttaaga
241 gaagaaatga ggacatatca gtatcgaaac tctgcagtga tgctcaagtt aaagtctttg
301 ggaaatgctg ccaactgaaa cctggaggag acagttcttc ctctttagat agttctgtga
361 cttcatcttc tgatataaaa gaccagtgtc ttaagtacca gggttctcgg tgctcttctg
421 atgccaatat gcttggagag atgatgtttg gctcagtagc aatgagctac aaaggatcca
481 ccttaaaaat tcatcagatt cgttcccctc cacagctcat gctcagcaaa gtgtttactg
541 ctcggactgg cagcagtatt tgtgggagtc tcaatacgct acaagatagt cttgaattca
601 tcaatcagga caacaataca ttaaaggctg ataataacac agttattaat ggactgcttg
661 gaaatatagg tctttcacag ttctgcagcc ccaggcgggc attctctgag cagggtccgc
721 tccgcctgat caggagcgcc tctttctttg cagttcacag caacccaatg gacatgcctg
781 gaagagagct caatgaggac agagacagtg gcatagcacg gtctgcatct ctcagcagct
841 tgctgatcac tccatttcct tccccaaact cctcacttac ccgaagttgt gccagcagct
901 accagcgacg ttggcgacgc agccaaacaa caagtttgga aaatggggta tttcctagat
961 ggtctataga agaaagcttt aatctctcag atgaaagctg tggccctaac ccaggaattg
1021 tgcggaaaaa gaagattgca attggggtaa tcttttcatt gtccaaagat gaagatgaaa
1081 ataacaaatt taatgaattc tttttttcac attttcctct ctttgaaagc cacatgaaca
1141 aattaaagag tgcaatagaa caggctatga aaatgagccg gagatcagct gatgccagtc
1201 agagaagttt ggcatataat cgaatagttg atgccctaaa tgaattcaga acaacaattt
1261 gtaatcttta cacgatgcca cgaattggag aacctgtctg gcttacaatg atgtcgggga
1321 ctccagaaaa gaaccacctt tgctatcgtt tcatgaagga gttcaccttt ctaatggaaa
1381 atgcttccaa aaatcaattc ttgccagctc tcattactgc agttctgacc aatcatcttg
1441 cctgggttcc aacagtcatg ccaaatggac aaccacctat aaaaatattt ttagaaaagc
1501 attcctctca gagtgtggac atgttggcaa agactcatcc atataaccca ctttgggcac
1561 aactgggaga cttgtatggc gctattggct ctcccgtacg gttagcaagg actgtggtag
1621 ttggcaaacg acaagacatg gtccagaggc tactttattt tcttacttat tttataagat
1681 gctctgaact tcaagaaacg catcttttag aaaatggaga agatgaagcc atcgttatgc
1741 caggcacagt aattactacc actttagaga aaggtgaaat agaagaatca gagtatgtcc
1801 ttgtcacaat gcatagaaac aaaagcagtt tgctctttaa agagtcagaa gaaattagaa
1861 ctcccaattg taactgtaaa tattgcagtc atccactcct tgggcaaaat gtagagaaca
1921 tttcacaaca agagagagaa gatattcaaa acagctctaa ggagctgcta ggaatttcag
1981 atgagtgccg gatgatttct ccttctgact gccaagaaga aaatgctgtt gatgttaaac
2041 agtacagaga taaattaaga acttgctttg acgccaagtt agagacagtt gtttgcacag
2101 gatctgttcc agtagacaaa tgtgcattgt cagagtcagg cttagagtca acagaggaaa
2161 catggcagag tgagaagttg ctggattcag acagtcacac aggcaaagca atgagatcca
2221 caggaatggt tgtggaaaaa aaacctccag ataagattgt gcctgcttca ttttcttgtg
2281 aggctgccca gacaaaggtt actttcctga ttggggattc tatgtcacct gattcagata
2341 ctgagcttcg aagtcaggca gtggtggatc agattaccag acatcacacc aaaccattga
2401 aggaagaaag aggggctatt gatcagcatc aagaaactaa acaaacaacc aaggaccaat
2461 ctggagagtc tgatacacag aacatggttt ctgaagagcc ctgtgaactt ccctgttgga
2521 atcattcaga cccagaaagc atgagcttat tcgacgaata ttttaatgat gattcaatcg
2581 aaaccaggac tattgatgat gttccattta aaacaagtac agatagtaaa gaccattgct
2641 gtatgttaga gttttcaaaa atattgtgta caaaaaataa caagcagaac aatgaatttt
2701 gtaaatgtat agaaacagtt ccccaagatt catgtaaaac ctgctttcct cagcaggacc
2761 aaagagatac actctccatt cttgtccccc atggggataa agagagttca gataaaaaaa
2821 ttgctgtagg aactgaatgg gacattccaa gaaatgaaag ttcagacagt gcccttgggg
2881 atagtgaaag tgaagataca ggtcatgata tgactagaca agttagcagt tattatggag
2941 gagagcaaga agattgggca gaagaggatg agataccttt tcctgggtca aagttaatcg
3001 aagtgagtgc tgttcagccc aacattgcca acttcgggag gtccttgctg ggtggctact
3061 gctcatctta tgtgcctgac tttgttcttc aaggaattgg gagtgatgag aggttccgtc
3121 agtgtctgat gtcagattta tctcatgctg tgcagcatcc agttttggat gaaccaatag
3181 cagaagctgt ctgtattata gctgacatgg ataaatggac tgttcaagtg gccagtagcc
3241 agagacgagt gacagataat aaattgggaa aggaagtatt ggtttccagt cttgtttcca
3301 atctgcttca ttccacactt cagctttata agcataactt gtctccaaat ttttgtgtaa
3361 tgcatcttga agaccggttg caggagctat acttcaaaag taaaatgctg tctgaatacc
3421 tgagggggca gatgcgtgtt catgtcaagg agctgggagt ggttctgggg attgaatcca
3481 gtgatcttcc acttctggct gctgtagcaa gcactcactc tccatatgtt gcacaaatac
3541 tcctttaata tacctaaaaa ttgttagaaa ttggtgggaa aataggtaga aaccaaggaa
3601 gcagacacaa catgcattta tggaga
//