LOCUS DQ084244 2277 bp mRNA linear HUM 21-APR-2006
DEFINITION Homo sapiens polycystic kidney disease 2-like 1 variant (PKD2L1)
mRNA, complete cds.
ACCESSION DQ084244
VERSION DQ084244.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2277)
AUTHORS Geng,L., Okuhara,D., Yu,Z., Tian,X., Cai,Y., Shibazaki,S. and
Somlo,S.
TITLE Polycystin-2 traffics to cilia independently of polycystin-1 by
using an N-terminal RVxP motif
JOURNAL J. Cell. Sci. 119 (PT 7), 1383-1395 (2006)
PUBMED 16537653
REFERENCE 2 (bases 1 to 2277)
AUTHORS Geng,L., Okuhara,D.Y., Yu,Z., Tian,X., Cai,Y. and Somlo,S.
TITLE Direct Submission
JOURNAL Submitted (27-MAY-2005) Department of Internal Medicine, Section of
Nephrology, Yale University School of Medicine, 333 Cedar, PO Box
208029, New Haven, CT 06520-8029, USA
FEATURES Location/Qualifiers
source 1..2277
/db_xref="H-InvDB:HIT000341098"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2277
/gene="PKD2L1"
CDS 1..2277
/gene="PKD2L1"
/note="ion channel"
/codon_start=1
/product="polycystic kidney disease 2-like 1 variant"
/protein_id="AAZ31363.1"
/translation="MNPRRRHTGPRCPAAASISVKASEASLPCPLGLWGTTLTENTAE
NRELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFFHTPSDTGVSFQ
AISSMADFWDFAQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRN
DSCVVHEDFREDILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSY
SGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVE
FPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRY
LSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYN
NMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYL
LFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLLNM
FLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQGGE
QEIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVA
LNTEIEKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETVLEGVVSQID
AVGSKLKMLERKGWLAPSPGVKEQAIWKHPQPAPAVTPDPWGVQGGQESEVPYKREEE
ALEERRLSRGEIPTLQRS"
BASE COUNT 548 a 599 c 607 g 523 t
ORIGIN
1 atgaacccca ggagacggca tacaggaccc aggtgtccag ctgctgcctc catatctgtc
61 aaggcatcag aggcatctct cccatgcccc ttaggacttt ggggaacaac cctgactgag
121 aacacagctg agaaccggga actttatatc aagaccaccc tgagggagct gttggtatat
181 attgtgttcc tggtggacat ctgtctacta acctatggaa tgacaagctc cagtgcttat
241 tactacacca aagtgatgtc tgagctcttc ttccatactc catcagacac tggagtctcc
301 tttcaggcca tcagcagcat ggcggacttc tgggattttg cccagggccc actactggac
361 agtttgtatt ggaccaaatg gtacaacaac cagagcctgg gccatggctc ccactccttc
421 atctactatg agaacatgct gctgggggtt ccgaggctgc ggcagctaaa ggtccgcaat
481 gactcctgtg tggtgcatga agacttccgg gaggacattc tgagctgcta tgatgtctac
541 tctccagaca aagaagaaca actccccttt gggcccttca atggcacagc gtggacatac
601 cactcgcagg atgagttggg gggcttctcc cactggggca ggctcacaag ctacagcgga
661 ggtggctact acctggacct tccaggatcc cgacagggta gtgcagaggc cctccgggcc
721 cttcaggagg ggctgtggct ggacaggggc actcgagtgg tgttcatcga cttctcagtc
781 tacaatgcca atatcaatct tttctgtgtc ctgaggctgg tggtggagtt tccagctaca
841 ggaggtgcca tcccatcctg gcaaatccgc acagtcaagc tgatccgcta tgtcagcaac
901 tgggacttct ttatcgttgg ctgtgaggtc atcttctgcg tcttcatctt ctactatgtg
961 gtggaagaga tcctggagct ccacattcac cggcttcgct acctcagcag catctggaac
1021 atactggacc tggtggtcat cttgctctcc attgtggctg tgggcttcca catattccga
1081 accctcgagg tgaatcggct catggggaag ctcctgcagc agccaaacac gtatgcagac
1141 tttgagttcc tcgccttctg gcagacacag tacaacaaca tgaatgctgt caacctcttc
1201 ttcgcctgga tcaagatatt caagtacatc agcttcaaca aaaccatgac ccagctctcc
1261 tccacgctgg cccgctgtgc caaggacatc ctgggcttcg ccgtcatgtt cttcattgtt
1321 ttcttcgcct atgcccaact cggctacctg cttttcggga cccaagtgga aaactttagc
1381 actttcatca agtgcatttt cactcagttc cggataatcc tcggggactt tgactacaat
1441 gctatcgaca atgccaaccg catcctgggc cctgcctact ttgtcaccta tgtcttcttc
1501 gtcttcttcg tgctcctgaa catgttcctg gccatcatca atgacacata ttcagaggtc
1561 aaggaggagc tggctggaca gaaggatgag ctgcaacttt ctgacctcct gaaacagggc
1621 tacaacaaga ccctactaag actgcgtctg aggaaggaga gggtttcgga tgtgcagaag
1681 gtcctgcagg gtggggagca ggagatccag tttgaggatt tcaccaacac cttaagggaa
1741 ctgggacacg cagagcatga aatcactgag ctcacggcca ccttcaccaa gtttgacaga
1801 gatgggaatc gtattctgga tgagaaggaa caggaaaaaa tgcgacagga cctggaggaa
1861 gagagggtgg ccctcaacac tgagattgag aaactaggcc gatctattgt gagcagccca
1921 caaggcaaat cgggtccaga ggctgccaga gcaggaggct gggtttcagg agaagaattc
1981 tacatgctca caaggagagt tctgcagctg gagactgtcc tggaaggagt agtgtcccag
2041 attgatgctg taggctcaaa gctgaaaatg ctggagagga aggggtggct ggctccctcc
2101 ccaggcgtga aggaacaagc tatttggaag cacccgcagc cagccccagc tgtgacccca
2161 gacccctggg gagtccaggg tgggcaggag agtgaggttc cctataaaag agaagaggaa
2221 gccttagagg agaggagact ctcccgtggt gagattccaa cgttgcagag gagttaa
//