LOCUS DQ082755 1774 bp mRNA linear HUM 30-AUG-2006
DEFINITION Homo sapiens mitochondrial acyl-CoA thioesterase 2 (ACOT2) mRNA,
complete cds; nuclear gene for mitochondrial product.
ACCESSION DQ082755
VERSION DQ082755.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1774)
AUTHORS Hunt,M.C., Rautanen,A., Westin,M.A., Svensson,L.T. and Alexson,S.E.
TITLE Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene
clusters shows that convergent, functional evolution results in a
reduced number of human peroxisomal ACOTs
JOURNAL FASEB J. 20 (11), 1855-1864 (2006)
PUBMED 16940157
REFERENCE 2 (bases 1 to 1774)
AUTHORS Hunt,M.C., Rautanen,A., Svensson,T.L. and Alexson,S.E.H.
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2005) Dept of Laboratory Medicine, Karolinska
University Hospital at Huddinge, Division of Clinical Chemistry
C1-74, SE 141 86 Stockholm, Sweden
FEATURES Location/Qualifiers
source 1..1774
/db_xref="H-InvDB:HIT000341084"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="14"
/map="14q24.3"
gene 1..1774
/gene="ACOT2"
CDS 183..1634
/gene="ACOT2"
/EC_number="3.1.2.2"
/function="hydrolysis of acyl-CoAs to free fatty acids and
coenzyme A"
/note="MTE-I; PTE2; ARTISt/p43"
/codon_start=1
/product="mitochondrial acyl-CoA thioesterase 2"
/protein_id="AAZ31237.1"
/translation="MSNKLLSPHPHSVVLRSEFKMASSPAVLRASRLYQWSLKSSAQF
LGSPQLRQVGQIIRVPARMAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRD
EKGALFQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDV
RTPLAVVLEVLDGHDPDPGRLLCQTRHERYFLPPGVRREPVRVGRVRGTLFLPPEPGP
FPGIVDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAMNY
LLSHPEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLRYKGETL
PPVGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWK
SEFYANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEP
RAHAMAQVDAWKQLQTFFHKHLGGREGTIPSKV"
BASE COUNT 343 a 489 c 528 g 414 t
ORIGIN
1 aaagcaaacc taggaagtag ctttccaaca taaagtggag gtttcaacac aggagacttt
61 aagcaagttc cagtgtgtct atatttggtc tggctgatcg gctggactct ggccttcccc
121 gctcacgtta gcagacagct ctgccctagt gggcgcttag cctgcgacgg cagcccgaga
181 ggatgtctaa caagcttctt tctccccacc cccattcagt tgttctcagg tctgaattca
241 aaatggcctc atctcctgct gtccttcgag cgtcccggct gtaccaatgg agcctgaaga
301 gttcggcgca gttcctgggg tctccacagc tgaggcaggt tggtcagatc attagggttc
361 ctgctcggat ggcggcgacg ctgatcctgg agcctgcggg ccgctgctgc tgggacgaac
421 cggtgcgaat cgccgtgcgc ggcctagccc cggagcagcc ggtcacgctg cgcgcgtccc
481 tgcgcgacga gaagggcgcg cttttccagg cccacgcgcg ctaccgcgcc gacactcttg
541 gcgagctgga cctggagcgc gcgcccgcgc tgggcggcag cttcgcgggg cttgagccca
601 tggggctgct ctgggccttg gagcccgaga aacctttggt gcggctggtg aagcgcgacg
661 tgcgaacgcc cttggccgtg gtgctggagg tgctggatgg ccacgacccc gaccccgggc
721 ggctgctgtg ccagacgcgg cacgagcgct acttcctccc gcccggggtg cggcgcgagc
781 cggtgcgcgt gggccgggtg cgaggcacgc tcttcctgcc gccagaacct gggccctttc
841 ctgggattgt ggacatgttc ggaactggag gtggcctgct ggagtatcgg gctagtctgc
901 tggctgggaa gggttttgct gtgatggctc tggcttatta taactatgaa gacctcccca
961 agaccatgga gacgctccat ctggagtact ttgaagaagc catgaactac ttgctcagtc
1021 atcccgaggt aaaaggtcca ggagttgggc tgcttggaat ttccaaaggg ggtgagctct
1081 gcctttccat ggcctctttc ctgaagggca tcacggctgc tgtcgtcatc aacggctctg
1141 tggccaatgt tgggggaacc ttacgctaca agggcgagac cctgccccct gtgggcgtca
1201 acagaaatcg catcaaggtg accaaagatg gctatgcaga cattgtggat gtcctgaaca
1261 gccctttgga aggacctgac cagaagagct tcattcctgt ggaaagggca gagagcacct
1321 tcctgttcct ggtaggtcag gatgaccaca actggaagag tgagttctat gctaatgagg
1381 cctgtaaacg cttgcaggcc catgggagga gaaagcccca gatcatctgt tacccagaga
1441 cagggcacta tattgagcct ccttacttcc ccctgtgtcg ggcttccctg catgccttgg
1501 tgggcagtcc tattatctgg ggaggggagc ccagggctca tgccatggct caggtggatg
1561 cttggaaaca actccagact ttcttccaca aacacttggg tggccgcgag gggacaatcc
1621 catcaaaagt gtaaatttta tttgatcatg tggcctctct gttgctaatc tctcctggaa
1681 acatctgcca catttagtgt gtgtatgtgt attcattctt ttgtttttaa taactaaagt
1741 tttttcccct cattattaaa atgaatttac cagt
//