LOCUS DQ082754 1603 bp mRNA linear HUM 30-AUG-2006
DEFINITION Homo sapiens acyl-CoA thioesterase 1 (ACOT1) mRNA, complete cds.
ACCESSION DQ082754
VERSION DQ082754.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1603)
AUTHORS Hunt,M.C., Rautanen,A., Westin,M.A., Svensson,L.T. and Alexson,S.E.
TITLE Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene
clusters shows that convergent, functional evolution results in a
reduced number of human peroxisomal ACOTs
JOURNAL FASEB J. 20 (11), 1855-1864 (2006)
PUBMED 16940157
REFERENCE 2 (bases 1 to 1603)
AUTHORS Hunt,M.C., Rautanen,A., Svensson,T.L. and Alexson,S.E.H.
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2005) Dept of Laboratory Medicine, Karolinska
University Hospital at Huddinge, Division of Clinical Chemistry
C1-74, SE 141 86 Stockholm, Sweden
FEATURES Location/Qualifiers
source 1..1603
/db_xref="H-InvDB:HIT000341083"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..1603
/gene="ACOT1"
CDS 199..1464
/gene="ACOT1"
/EC_number="3.1.2.2"
/function="hydrolysis of acyl-CoAs to free fatty acids and
coenzyme A"
/note="CTE-Ia"
/codon_start=1
/product="acyl-CoA thioesterase 1"
/protein_id="AAZ31236.1"
/translation="MAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGA
LFQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPL
AVELEVLDGHDPDPGRLLCRVRHERYFLPPGVRREPVRAGRVRGTLFLPPEPGPFPGI
VDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSH
PEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLRYKGETLPPVG
VNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFY
ANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEPRAHA
MAQVDAWKQLQTFFHKHLGGHEGTIPSKV"
BASE COUNT 298 a 444 c 495 g 366 t
ORIGIN
1 ctttaagcaa gttccagtgt gtctatattt ggtctggctg atcggctgga ctctggcctt
61 ccccgctcac attagcagac agctctgccc tagtgggcgt ttagcctgcg acggcagccc
121 gagaggaaga gttgggcaga gttgcagggg tctccacagc tgaggcagtt tggccggatt
181 atttgggttc ctgctcggat ggcggcgacg ctgatcctgg agcccgcggg ccgctgctgc
241 tgggacgaac cggtgcgaat cgccgtgcgc ggcctagccc cggagcagcc ggtcacgctg
301 cgcgcgtccc tgcgcgacga gaagggcgcg cttttccagg cccacgcgcg ctaccgcgcc
361 gacacccttg gcgagctgga cctggagcgc gcgcccgcgc tgggcggcag cttcgcgggg
421 cttgagccca tggggctgct ctgggccttg gagcccgaga aacccttggt gcggctggtg
481 aagcgcgacg tgcgaacgcc cttggccgtg gagctggagg tgctggatgg ccacgacccc
541 gaccccgggc ggctgctgtg ccgggtgcgg cacgagcgct acttcctccc gcccggggtg
601 cggcgcgagc cggtgcgcgc gggccgggtg cgaggcacgc tcttcctgcc gccagaacct
661 gggccctttc ctggcattgt ggacatgttc ggaactggag gtggcctgct ggagtatcgg
721 gctagtctgc tggctgggaa gggttttgct gtgatggctc tggcttacta taactatgaa
781 gacctcccca agaccatgga gacgctccat ctggagtact ttgaagaagc tgtgaactac
841 ttgctcagtc atcctgaggt aaaaggtcca ggagttgggc tgcttggaat ttccaaaggg
901 ggtgagctct gcctttccat ggcctctttc ctgaagggca tcacggctgc tgtcgtcatc
961 aacggctctg tggccaatgt tgggggaacc ttacgctaca agggcgagac cctgccccct
1021 gtgggcgtca acagaaatcg catcaaggtg accaaagatg gctatgcaga cattgtggat
1081 gtcctgaaca gccctttgga aggacctgac cagaagagct tcattcctgt ggaaagggca
1141 gagagcacct tcctgttcct ggtaggtcag gatgaccaca actggaagag tgagttctat
1201 gctaatgagg cctgtaaacg cttgcaggcc catgggagga gaaagcccca gatcatctgt
1261 tacccagaga cagggcacta tattgagcct ccttacttcc ccctgtgtcg ggcttccctg
1321 catgccttgg tgggcagtcc tattatctgg ggaggggagc ccagggctca tgccatggct
1381 caggtggatg cttggaaaca actccagact ttcttccaca aacacttggg tggccacgag
1441 gggacaatcc catcaaaagt gtaaatttta tttgatcatg tggcctctct gttgctaatc
1501 tctcctggaa acatctgcca catttagtgt gtgtatgtgt attcattctt tctcataact
1561 tcttaaagtt tcttcccctc attattaaaa tgaatttacc agt
//