LOCUS DQ009660 6560 bp mRNA linear HUM 08-MAY-2005
DEFINITION Homo sapiens expressed in synovial lining protein (FNDC1) mRNA,
complete cds.
ACCESSION DQ009660
VERSION DQ009660.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6560)
AUTHORS Seki,T., Selby,J., Haupl,T. and Winchester,R.
TITLE Use of differential subtraction method to identify genes that
characterize the phenotype of cultured rheumatoid arthritis
synoviocytes
JOURNAL Arthritis Rheum. 41 (8), 1356-1364 (1998)
PUBMED 9704633
REFERENCE 2 (bases 1 to 6560)
AUTHORS Winchester,R.J., Wang,R., Zhang,H.-Z., Selby,J., Friedman,R.A. and
Seki,T.
TITLE Direct Submission
JOURNAL Submitted (15-APR-2005) Herbert Irving Comprehensive Cancer Center,
Columbia University, Box 95 - 630 W. 168th Street, New York, NY
10032, USA
FEATURES Location/Qualifiers
source 1..6560
/db_xref="H-InvDB:HIT000340972"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6q25.3"
gene 1..6560
/gene="FNDC1"
/note="ML2115; ESP"
5'UTR 1..356
/gene="FNDC1"
misc_feature 201
/gene="FNDC1"
/note="possible alternate site of translation initiation"
CDS 357..5867
/gene="FNDC1"
/inference="non-experimental evidence, no additional
details recorded"
/note="SH2 domain-binding protein; fibronectin domain
containing protein"
/codon_start=1
/product="expressed in synovial lining protein"
/protein_id="AAY26234.1"
/translation="MGLKVTWDPPKDATSRPVEHYNIAYGKSLKSLKYIKVNAETYSF
LIEDVEPGVVYFVLLTAENHSGVSRPVYRAESPPGGEWIEIDGFPIKGPGPFNETVTE
KEVPNKPLRVRVRSSDDRLSVAWKAPRLSGAKSPRRSRGFLLGYGESGRKMNYVPLTR
DERTHEIKKLASESVYVVSLQSMNSQGRSQPVYRAALTKRKISEEDELDVPDDISVRV
MSSQSVLVSWVDPVLEKQKKVVASRQYTVRYREKGELARWDYKQIANRRVLIENLIPD
TVYEFAVRISQGERDGKWSTSVFQRTPESAPTTAPENLNVWPVNGKPTVVAASWDALP
ETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATNRRGLG
PHSKAFIVAMPTTSKADVEQNTEDNGKPEKPEPSSPSPRAPASSQHPSVPASPQGRNA
KDLLLDLKNKILANGGAPRKPQLRAKKAEELDLQSTEITGEEELGSREDSPMSPSDTQ
DQKRTLRPPSRHGHSVVAPGRTAVRARMPALPRREGVDKPGFSLATQPRPGAPPSASA
SPAHHASTQGTSHRPSLPASLNDNDLVDSDEDERAVGSLHPKGAFAQPRPALSPSRQS
PSSVLRDRSSVHPGAKPASPARRTPHSGAAEEDSSASAPPSRLSPPHGGSSRLLPTQP
HLSSPLSKGGKDGEDAPATNSNAPSRSTMSSSVSSHLSSRTQVSEGAEASDGESHGDG
DREDGGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQ
STVPSRAHPRVPSHSDSHPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWED
LRRSPQRGASLHRKEPIPENPKSTGADTHPQGKYSSLASKAQDVQQSTDADTEGHSPK
AQPGSTDRHASPARPPAARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDA
GRSPSQPRLSLTQAGRPRPTSQGRSHSSSDPYTASSRGMLPTALQNQDEDAQGSYDDD
STEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGAGGDHRSQRGHAASPARPSR
PGGPQSRARVPSRAAPGKSEPPSKRPLSSKSQQSVSAEDDEEEDAGFFKGGKEDLLSS
SVPKWPSSSTPRGGKDADGSLAKEEREPAIALAPRGGSLAPVKRPLPPPPGSSPRASH
VPSRLPPRSAATVSPVAGTHPWPQYTTRAPPGHFSTTPMLSLRQRMMHARFRNPLSRQ
PARPSYRQGYNGRPNVEGKVLPGSNGKPNGQRIINGPQGTKWVVDLDRGLVLNAEGRY
LQDSHGNPLRIKLGGDGRTIVDLEGTPVVSPDGLPLFGQGRHGTPLANAQDKPILSLG
GKPLVGLEVIKKTTHPPTTTMQPTTTTTPLPTTTTPRPTTATTRRTTTRRPTTTVRTT
TRTTTTTTPKPTTPIPTCPPGTLERHDDDGNLIMSSNGIPECYAEEDEFSGLETDTAV
PTEEAYVIYDEDYEFETSRPPTTTEPSTTATTPRVIPEEGAISSFPEEEFDLAGRKRF
VAPYVTYLNKDPSAPCSLTDALDHFQVDSLDEIIPNDLKKSDLPPQHAPRNITVVAVE
GCHSFVIVDWDKATPGDVVTGYLVYSASYEDFIRNKWSTQASSVTHLPIENLKPNTRY
YFKVQAQNPHGYGPISPSVSFVTESDNPLLVVRPPGGEPIWIPFAFKHDPSYTDCHGR
QYVKRTWYRKFVGVVLCNSLRYKIYLSDNLKDTFYSIGDSWGRGEDHCQFVDSHLDGR
TGPQSYVEALPTIQGYYRQYRQEPVRFGNIGFGTPYYYVGWYECGVSIPGKW"
variation 4635^4636
/gene="FNDC1"
/frequency=".15"
/replace="cccgccgcacgaccacca"
3'UTR 5868..6560
/gene="FNDC1"
polyA_site 6533
/gene="FNDC1"
BASE COUNT 1556 a 2048 c 1696 g 1260 t
ORIGIN
1 ctcagtggcg gagcgcggct gccggtgtgc ggccgggagc gatcgccgcg gggcaggggc
61 gcggcgggca ccgcgcagag cgcgcagaac agacggacgg cggcggggac ccgacggcgg
121 cgcctcggca ctccccagac tccggccagc gcccccctgc cagccgcaag cacccagccc
181 cggcccaccc cgggctctcg atggcccccg aggccggggc gaccctgcgc gcgccgcgcc
241 ggctgtcctg ggcggcgctg ctgctcttgg ccgcgctgct ccccgtcgcc tcctcggcgg
301 cggccccagt tgaccaccca ctgaagccaa ggcatgtgaa actgctgtcc actaaaatgg
361 gcctgaaagt cacgtgggac ccacccaaag atgctaccag tagacctgtg gagcattaca
421 acattgccta tgggaagtca ctgaaaagtc ttaaatacat caaggtgaat gcggagacat
481 actccttcct tattgaggat gtggagccgg gggtagtgta ctttgtgctg cttactgcag
541 aaaaccacag tggagtgagc cgtcctgttt acagagctga aagcccacct ggaggtgaat
601 ggatcgagat tgatggtttt cccattaagg gtccaggacc atttaatgaa accgtcacag
661 aaaaggaagt gcccaacaag cccttgcgtg tgcgtgtccg gtcctcagat gacaggctgt
721 ccgttgcgtg gaaggcacca cgcctgtctg gagccaagag tccacgcaga tcacggggtt
781 ttctcctggg ctacggggag agtggccgga agatgaatta tgttccactg acaagagatg
841 aacggacaca cgaaattaaa aagctagcct cggaatccgt gtatgtggtc tccctgcagt
901 ccatgaactc tcagggccgg agccaaccag tctacagggc tgccctaaca aagcgaaaga
961 tttcagaaga ggacgaattg gatgtacctg acgacatcag cgtccgggtt atgtcatctc
1021 agtctgtgct tgtgtcctgg gtggatcctg ttctggaaaa acagaagaaa gttgttgcat
1081 caagacagta caccgtgcgc tatcgagaga agggggaatt ggccaggtgg gattataagc
1141 agatcgctaa caggcgtgtg ctgattgaga acctgattcc agacactgtg tatgaatttg
1201 cagtccgtat ttcacagggt gaaagagatg gcaaatggag tacgtcagtc ttccaaagaa
1261 caccagaatc tgcccctacc acagctcctg aaaacttgaa cgtctggcca gtcaatggca
1321 aacctacagt tgtcgctgca tcttgggatg cgctaccaga gactgagggg aaagtgaaag
1381 aatacattct ttcatacgcc ccggctctca aaccatttgg agcaaagtcc ctcacctatc
1441 ctggagacac tacttctgcc ctggtggatg gtctgcagcc tggggaacgc tatcttttca
1501 aaatccgggc cacaaacagg agaggcctgg gacctcactc caaagccttc attgtcgcta
1561 tgccaacaac cagtaaggcg gatgttgagc agaacacgga ggacaatggg aaacccgaaa
1621 aacctgagcc ttcctcacct tctcccagag ctccagcttc ctcccaacac ccctctgtgc
1681 ctgcttctcc ccaagggaga aatgccaagg accttcttct tgacttgaag aacaaaatat
1741 tggctaatgg tggggcgccc cgaaaacccc agcttcgcgc caagaaggca gaggagctgg
1801 atcttcagtc gacagaaatc actggggagg aggagctggg ttcccgggag gactcgccca
1861 tgtcaccctc agacacccaa gaccagaaac ggaccctgag gccgccaagt agacacggcc
1921 actcggtggt tgctcccggc aggactgcag tgagggcccg gatgccagcg ctgccccgaa
1981 gggaaggcgt agataagcct ggcttttccc tggccacgca gccccgccca ggggcgcccc
2041 cctcggcttc ggcctctcct gcccaccacg cgtccaccca gggcacctct catcgtcctt
2101 ccctgcctgc cagcttgaat gacaacgact tggtggactc agacgaagat gagcgcgctg
2161 tgggctccct ccaccccaag ggcgccttcg cccagccccg gccagccctg tcccccagcc
2221 gccagtcccc gtccagcgtt ctccgcgaca gaagctctgt gcaccccggc gcaaagccag
2281 cctcgccggc ccggaggacc ccccattcag gggccgcaga ggaagattcc agtgcctcag
2341 ccccaccctc aagactttct ccaccccatg ggggatcatc tcggctgctg cccacccagc
2401 cacacctgag ctctccactt tccaagggcg ggaaggatgg tgaggacgcc ccagccacca
2461 actccaatgc gccatcacgg tccaccatgt cctcctccgt ctcttctcat ctctcgtcca
2521 ggacgcaggt ctctgaggga gcggaggctt ctgatggtga aagccacggt gacggcgata
2581 gggaagacgg cggaaggcag gcggaggcca cggcccagac gctgcgggcc cggcctgcct
2641 ctggacactt ccatttgctc agacacaaac cctttgctgc caacgggagg tctccaagca
2701 ggttcagcat tgggcgggga cctcggctgc agccctccag ctccccacag tcgactgtgc
2761 cctcccgagc ccaccccagg gttccctctc actctgattc ccaccctaag cttagctcag
2821 gtatccatgg agacgaggag gatgagaagc cgcttcctgc caccgttgtc aatgaccacg
2881 tgccttcctc ctccaggcag cccatctccc ggggctggga ggacttaagg agaagcccgc
2941 agagaggggc cagcctgcat cggaaggaac ccatcccaga gaaccccaaa tccacagggg
3001 cagatacaca tcctcagggc aagtactcct ccctggcctc caaggctcag gatgttcaac
3061 agagcacaga cgcggacacg gagggtcatt ctcccaaagc acagccaggg tccacagacc
3121 gccacgcgtc ccctgctcgt ccgcccgcag cacggtcaca gcagcatccc agtgttccca
3181 gaaggatgac acccggccgg gccccacaac agcagccccc tcctcccgtc gccacgtccc
3241 agcaccaccc gggaccccag agcagagacg cgggtcggtc accttcccag cccaggctct
3301 cactgaccca ggccgggcgg ccccgcccca cgtcgcaggg ccgctcccac tcctcctcgg
3361 acccttacac ggcgagctcc agagggatgc tccccacggc cctccagaac caggacgagg
3421 atgcccaggg cagctacgac gacgacagca cagaagtcga ggcccaggat gtgcgggccc
3481 ccgcgcacgc cgcgcgcgcc aaggaggcag ctgcgtccct tcccaagcac cagcaggtgg
3541 agtctcccac aggcgcaggg gcaggtggcg accacaggtc ccagcgcgga catgcggcct
3601 cccccgccag gcccagccga cccggcggcc cccagtcccg cgcccgggta cccagcaggg
3661 cagcgccggg gaagtcggag cctccttcca agcggcccct gtcctccaag tcccagcagt
3721 cggtctcagc cgaggacgac gaggaggagg acgcgggatt ttttaaaggc gggaaagaag
3781 accttctgtc ttcctctgtg ccaaagtggc cctcttcctc cactcccagg ggcggcaaag
3841 acgccgatgg gagcctcgcc aaggaagaga gggagcctgc catcgcgctt gcccctcgcg
3901 gagggagcct ggctcctgtg aagcgacctc tccccccacc tccaggcagc tcccccaggg
3961 cctcccacgt cccttcccga ctgccgcctc gcagcgctgc caccgtgagc cccgtcgcgg
4021 gcacccaccc ctggccgcag tacaccacgc gcgccccacc tggccacttc tccaccaccc
4081 cgatgctgtc cttgcgccag aggatgatgc atgccagatt ccgtaaccct ctctcccgac
4141 agcctgccag accctcttac agacaaggtt ataatggcag accaaatgta gaagggaaag
4201 tccttcctgg tagtaatgga aaaccgaatg gacagagaat tatcaatggc cctcaaggaa
4261 caaagtgggt tgtggacctt gatcgtgggt tagtattgaa tgcagaagga aggtacctcc
4321 aagattcaca tggaaatcct cttcggatta aactaggagg agatggtcga accattgtag
4381 atctggaagg gacccccgtg gtgagtcctg acggcctccc actctttggg caggggcgac
4441 atggcacacc tctggccaat gcccaagata agccaatttt gagtcttgga ggaaagccgc
4501 tggtgggctt ggaggtcatc aaaaaaacca cccatccccc taccactacc atgcagccca
4561 ccactactac gacgcccctg cctaccacta caaccccgag gcccaccact gccaccaccc
4621 gccgcacgac caccaggcgt ccaacaacca cagtccgaac cactacgcgg acaaccacca
4681 ccaccacccc caaacccacc actcccatcc ccacctgtcc ccctgggacc ttggaacggc
4741 acgacgatga tggcaacctg ataatgagct ccaatgggat cccagagtgc tacgctgaag
4801 aagatgagtt ctcaggcttg gagactgaca ctgcagtacc tacggaagag gcctacgtta
4861 tatatgatga agattatgaa tttgagacgt caaggccacc aaccaccact gagccttcga
4921 ccactgctac cacaccgagg gtgatcccag aggaaggcgc catcagttcc tttcctgaag
4981 aagaatttga tctggctgga aggaaacgat ttgttgctcc ttacgtgacg tacctaaata
5041 aagacccatc agccccgtgc tctctgactg atgcactgga tcacttccaa gtggacagcc
5101 tggatgaaat catccccaat gacctgaaga agagtgacct gcctccccag catgctcccc
5161 gcaacatcac cgtggtggcc gtggaaggtt gccactcatt tgtcattgtg gactgggaca
5221 aagccacccc aggagatgtg gtcacaggtt acttggttta cagtgcatcc tatgaagact
5281 tcatcaggaa caagtggtcc actcaagctt catcagtaac tcacttgccc attgagaacc
5341 taaagcccaa cacgaggtat tattttaaag tgcaagcaca aaatcctcat ggctacggac
5401 ctatcagccc ttcggtctca tttgtcaccg aatcagataa tcctctgctt gttgtgaggc
5461 ccccaggcgg tgagcctatc tggatcccat tcgctttcaa acatgatccc agctacacgg
5521 actgccatgg acggcaatat gtgaagcgca cgtggtatcg aaagttcgtg ggagttgttc
5581 tttgtaattc actgaggtat aaaatctacc tcagtgacaa cctgaaagat acattctaca
5641 gcattggaga cagctgggga agaggtgaag accattgcca atttgtggat tcacaccttg
5701 atggaagaac agggcctcag tcctatgtag aagccctccc tactattcaa ggctactatc
5761 gccagtatcg tcaggagcct gtcaggtttg ggaacatcgg cttcggaacc ccctactact
5821 atgtgggctg gtacgagtgt ggggtctcca tccctggaaa gtggtaatca caggaccgtc
5881 atgctgcaag cttgccctgc ccagccccac caactaagtc gcactagggg ctgtgagcaa
5941 agacagccag cgtgctcagc cccgctgccc taggtgccag gaaggtcata gatggacact
6001 ggccattctg gtcatctcag tctggaactc agtcccactt cttggcctgg acaatgaaca
6061 ggattcagtt ttgctgttaa ctttgcttct ctactttttt ttgtttgttt gtaatagcac
6121 atcccagaga catcagaaac cagcaactga ttcagtgtga tttccagact ttttaggcat
6181 gaaattcgga cacttcagta tttccaggaa tagcatatgc acgctgttct tgcttcatgg
6241 aatgctacat gctttctgtt tttctcattt tggatttctc caaaactaac tgaatttaag
6301 cttcaggtcc ctttgtatgc agtagaaagg aattattaaa aacaccacca aagaaaataa
6361 atatatccta cttgaaattt actctatgga cttacccact gctagaataa atgtatcaaa
6421 tcttatttgt aaattctcaa ttttgatata tatatgtata tatgcatata catatccaca
6481 cttgtctgca agaatattga ttaaaattgc taaatttgta cttgttcacc agaaaaaaaa
6541 aaaaaaaaaa aaaaaaaaaa
//