LOCUS HUMGDCMR 3783 bp mRNA linear HUM 07-DEC-2007
DEFINITION Homo sapiens mRNA for glycine decarboxylase, complete cds.
ACCESSION D90239
VERSION D90239.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Kume,A., Koyata,H., Sakakibara,T., Ishiguro,Y., Kure,S. and
Hiraga,K.
TITLE The glycine cleavage system: Molecular cloning of the chicken and
human glycine decarboxylase cDNAs and some characteristics
involved in the deduced protein structures
JOURNAL J. Biol. Chem. 266, 3323-3329 (1991)
COMMENT These data kindly submitted in computer readable form by:
Koichi Hiraga
Department of Biochemistry
Toyama Medical and Pharmaceutical University
School of Medicine
2630 Sugitani, Toyama
Toyama 930-01
Japan
FEATURES Location/Qualifiers
source 1..3783
/db_xref="H-InvDB:HIT000102074"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="liver"
CDS 151..3213
/codon_start=1
/product="glycine decarboxylase precursor"
/protein_id="BAA14286.1"
/translation="MQSCARAWGLRLGRGVGGGRRLAGGSGPCWAPRSRDSSSGGGDS
AAAGASRLLERLLPRHDDFARRHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLK
RPLKMEDPVCENEILATLHAISSKNQIWRSYIGMGYYNCSVPQTILRNLLENSGWITQ
YTPYQPEVSQGRLESLLNYQTMVCDITGLDMANASLLDEGTAAAEALQLCYRHNKRRK
FLVDPRCHPQTIAVVQTRAKYTGVLTELKLPCEMDFSGKDVSGVLFQYPDTEGKVEDF
TELVERAHQSGSLACCATDLLALCILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFF
AVRESLVRMMPGRMVGVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMA
AMFRIYHGSHGLEHIARRVHNATLILSEGLKRAGHQLQHDLFFDTLKIHCGCSVKEVL
GRAAQRQINFRLFEDGTLGISLDETVNEKDLDDLLWIFGCESSAELVAESMGEECRGI
PGSVFKRTSPFLTHQVFNSYHSETNIVRYMKKLENKDISLVHSMIPLGSCTMKLNSSS
ELAPITWKEFANIHPFVPLDQAQGYQQLFRELEKDLCELTGYDQVCFQPNSGAQGEYA
GLATIRAYLNQKGEGHRTVCLIPKSAHGTNPASAHMAGMKIQPVEVDKYGNIDAVHLK
AMVDKHKENLAAIMITYPSTNGVFEENISDVCDLIHQHGGQVYLDGANMNAQVGICRP
GDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPFLPNHPVISLKRNEDACPVG
TVSAAPWGSSSILPISWAYIKMMGGKGLKQATETAILNANYMAKRLETHYRILFRGAR
GYVGHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVAGTLMVEPTESEDKA
ELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSHWDRPYSREVAAFP
LPFMKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS"
sig_peptide 151..267
/note="glycine decarboxylase signal peptide"
mat_peptide 268..3210
/product="glycine decarboxylase"
misc_feature 2410..2412
/note="pyridoxal phosphate binding site (K754)"
BASE COUNT 950 a 899 c 1028 g 906 t
ORIGIN
1 cccgcgagcg tccatccatc tgtccggccg actgtccagc gaaaggggct ccaggccggg
61 cgcacgtcga cccgggggac cgaggccagg agaggggcca agagcgcggc tgacccttgc
121 gggccggggc aggggacggt ggccgcggcc atgcagtcct gtgccagggc gtgggggctg
181 cgcctgggcc gcggggtcgg gggcggccgc cgcctggctg ggggatcggg gccgtgctgg
241 gcgccgcgga gccgggacag cagcagtggc ggcggggaca gcgccgcggc tggggcctcg
301 cgcctcctgg agcgccttct gcccagacac gacgacttcg ctcggaggca catcggccct
361 ggggacaaag accagagaga gatgctgcag accttggggc tggcgagcat tgatgaattg
421 atcgagaaga cggtccctgc caacatccgt ttgaaaagac ccttgaaaat ggaagaccct
481 gtttgtgaaa atgaaatcct tgcaactctg catgccattt caagcaaaaa ccagatctgg
541 agatcgtata ttggcatggg ctattataac tgctcagtgc cacagacgat tttgcggaac
601 ttactggaga actcaggatg gatcacccag tatactccat accagcctga ggtgtctcag
661 gggaggctgg agagtttact caactaccag accatggtgt gtgacatcac aggcctggac
721 atggccaatg catccctgct ggatgagggg actgcagccg cagaggcact gcagctgtgc
781 tacagacaca acaagaggag gaaatttctc gttgatcccc gttgccaccc acagacaata
841 gctgttgtcc agactcgagc caaatatact ggagtcctca ctgagctgaa gttaccctgt
901 gaaatggact tcagtggaaa agatgtcagt ggagtgttgt tccagtaccc agacacggag
961 gggaaggtgg aagactttac ggaactcgtg gagagagctc atcagagtgg gagcctggcc
1021 tgctgtgcta ctgacctttt agctttgtgc atcttgaggc cacctggaga atttggggta
1081 gacatcgccc tgggcagctc ccagagattt ggagtgccac tgggctatgg gggaccccat
1141 gcagcatttt ttgctgtccg agaaagcttg gtgagaatga tgcctggaag aatggtgggg
1201 gtaacaagag atgccactgg gaaagaagtg tatcgtcttg ctcttcaaac cagggagcaa
1261 cacattcgga gagacaaggc taccagcaac atctgtacag ctcaggccct cttggcgaat
1321 atggctgcca tgtttcgaat ctaccatggt tcccatgggc tggagcatat tgctaggagg
1381 gtacataatg ccactttgat tttgtcagaa ggtctcaagc gagcagggca tcaactccag
1441 catgacctgt tctttgatac cttgaagatt cattgtggct gctcagtgaa ggaggtcttg
1501 ggcagggcgg ctcagcggca gatcaatttt cggctttttg aggatggcac acttggtatt
1561 tctcttgatg aaacagtcaa tgaaaaagat ctggacgatt tgttgtggat ctttggttgt
1621 gagtcatctg cagaactggt tgctgaaagc atgggagagg agtgcagagg tattccaggg
1681 tctgtgttca agaggaccag cccgttcctc acccatcaag tgttcaacag ctaccactct
1741 gaaacaaaca ttgtccggta catgaagaaa ctggaaaata aagacatttc ccttgttcac
1801 agcatgattc cactgggatc ctgcaccatg aaactgaaca gttcgtctga actcgcacct
1861 atcacatgga aagaatttgc aaacatccac ccctttgtgc ctctggatca agctcaagga
1921 tatcagcagc ttttccgaga gcttgagaag gatttgtgtg aactcacagg ttatgaccag
1981 gtctgtttcc agccaaacag cggagcccag ggagaatatg ctggactggc cactatccga
2041 gcctacttaa accagaaagg agaggggcac agaacggttt gcctcattcc gaaatcagca
2101 catgggacca acccagcaag tgcccacatg gcaggcatga agattcagcc tgtggaggtg
2161 gataaatatg ggaatatcga tgcagttcac ctcaaggcca tggtggataa gcacaaggag
2221 aacctagcag ctatcatgat tacataccca tccaccaatg gggtgtttga agagaacatc
2281 agtgacgtgt gtgacctcat ccatcaacat ggaggacagg tctacctaga cggggcaaat
2341 atgaatgctc aggtgggaat ctgtcgccct ggagacttcg ggtctgatgt ctcgcaccta
2401 aatcttcaca agaccttctg cattccccac ggaggaggtg gtcctggcat ggggcccatc
2461 ggagtgaaga aacatctcgc cccgtttttg cccaatcatc ccgtcatttc actaaagcgg
2521 aatgaggatg cctgtcctgt gggaaccgtc agtgcggccc catggggctc cagttccatc
2581 ttgcccattt cctgggctta tatcaagatg atgggaggca agggtcttaa acaagccacg
2641 gaaactgcga tattaaatgc caactacatg gccaagcgat tagaaacaca ctacagaatt
2701 cttttcaggg gtgcaagagg ttatgtgggt catgaattta ttttggacac gagacccttc
2761 aaaaagtctg caaatattga ggctgtggat gtggccaaga gactccagga ttatggattt
2821 cacgccccta ccatgtcctg gcctgtggca gggaccctca tggtggagcc cactgagtcg
2881 gaggacaagg cagagctgga cagattctgt gatgccatga tcagcattcg gcaggaaatt
2941 gctgacattg aggagggccg catcgacccc agggtcaatc cgctgaagat gtctccacac
3001 tccctgacct gcgttacatc ttcccactgg gaccggcctt attccagaga ggtggcagca
3061 ttcccactcc ccttcatgaa accagagaac aaattctggc caacgattgc ccggattgat
3121 gacatatatg gagatcagca cctggtttgt acctgcccac ccatggaagt ttatgagtct
3181 ccattttctg aacaaaagag ggcgtcttct tagtcctctc tccctaagtt taaaggactg
3241 atttgatgcc tctccccaga gcatttgata agcaagaaag atttcatctc ccaccccagc
3301 ctcaagtagg agttttatat actgtgtata tctctgtaat ctctgtcaag gtaaatgtaa
3361 atacagtagc tggagggagt cgaagctgat ggttggaaga cggatttgct ttggtattct
3421 gcttccacat gtgccagttg cctggattgg gagccatttt gtgttttgcg tagaaagttt
3481 taggaacttt aacttttaat gtggcaagtt tgcagatgtc atagaggcta tcctggagac
3541 ttaatagaca tttttttgtt ccaaaagagt ccatgtggac tgtgccatct gtgggaaatc
3601 ccagggcaaa tgtttacatt ttgtataccc tgaagaactc tttttcctct aatatgccta
3661 atctgtaatc acatttctga gtgttttcct ctttttctgt gtgaggtttt tttttttttt
3721 aatctgcatt tattagtatt ctaataaaag cattttgatc ggaaaaaaaa aaaaaaaaaa
3781 aaa
//