LOCUS D87931 4363 bp mRNA linear HUM 18-MAR-2006
DEFINITION Homo sapiens mRNA for Rho kinase, complete cds.
ACCESSION D87931
VERSION D87931.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4363)
AUTHORS Takahashi,N.
TITLE Direct Submission
JOURNAL Submitted (17-SEP-1996) to the DDBJ/EMBL/GenBank databases.
Contact:Nobuaki Takahashi
Kirin brewery co., ltd., centarl laboratries for key technology;
1-13-5, Fukuura kanazawa-ku, yokohama, kanagawa 236, Japan
REFERENCE 2
AUTHORS Takahashi,N., Tuiki,H., Saya,H. and Kaibuchi,K.
TITLE Localization of the gene coding for ROCK II/Rho kinase on human
chromosome 2p24
JOURNAL Genomics 55, 235-237 (1999)
COMMENT
FEATURES Location/Qualifiers
source 1..4363
/chromosome="2"
/db_xref="H-InvDB:HIT000101980"
/db_xref="taxon:9606"
/map="2p24"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="brain"
CDS 1..4167
/codon_start=1
/product="Rho kinase"
/protein_id="BAA75636.1"
/transl_table=1
/translation="MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVE
SLLDGLNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIKGLQMKAEDYDVVKVIGRGA
FGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQ
DDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPD
NMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECD
WWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLT
DREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKG
DVETFPIPKAFVGNQLPFIGFTYYRENLLLSDSPSCRENDSIQSRKNEESQEIQKKLY
TLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQLEREKALL
QHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDE
TNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQ
SALESERRDRTHGSEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKE
KSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKL
LEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQ
ETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDAD
GQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQ
LEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLE
ETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTL
KTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKEL
NEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPGDAEADD
GFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLDIDK
LFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKGHE
FIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYD
ISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRP
SRQLAPNKPS"
BASE COUNT 1587 a 769 c 990 g 1017 t
ORIGIN
1 atgagccggc ccccgccgac ggggaaaatg cccggcgccc ccgagaccgc gccgggggac
61 ggggcaggcg cgagccgcca gaggaagctg gaggcgctga tccgagaccc tcgctccccc
121 atcaacgtgg agagcttgct ggatggctta aattccttgg tccttgattt agattttcct
181 gctttgagga aaaacaagaa catagataat ttcttaaata gatatgagaa aattgtgaaa
241 aaaatcaaag gtctacagat gaaggcagaa gactatgatg ttgtaaaagt tattggaaga
301 ggtgcttttg gtgaagtgca gttggttcgt cacaaggcat cgcagaaggt ttatgctatg
361 aagcttctta gtaagtttga aatgataaaa agatcagatt ctgccttttt ttgggaagaa
421 agagatatta tggcctttgc caatagcccc tgggtggttc agctttttta tgcctttcaa
481 gatgataggt atctgtacat ggtaatggag tacatgcctg gtggagacct tgtaaacctt
541 atgagtaatt atgatgtgcc tgaaaaatgg gccaaatttt acactgctga agttgttctt
601 gctctggatg caatacactc catgggttta atacacagag atgtgaagcc tgacaacatg
661 ctcttggata aacatggaca tctaaaatta gcagattttg gcacgtgtat gaagatggat
721 gaaacaggca tggtacattg tgatacagca gttggaacac cggattatat atcacctgag
781 gttctgaaat cacaaggggg tgatggtttc tatgggcgag aatgtgattg gtggtctgta
841 ggtgttttcc tttatgagat gctagtgggg gatactccat tttatgcgga ttcacttgta
901 ggaacatata gcaaaattat ggatcataag aattcactgt gtttccctga agatgcagaa
961 atttccaaac atgcaaagaa tctcatctgt gctttcttaa cagataggga ggtacgactt
1021 gggagaaatg gggtggaaga aatcagacag catcctttct ttaagaatga tcagtggcat
1081 tgggataaca taagagaaac ggcagctcct gtagtacctg aactcagcag tgacatagac
1141 agcagcaatt tcgatgacat tgaagatgac aaaggagatg tagaaacctt cccaattcct
1201 aaagcttttg ttggaaatca gctgcctttc atcggattta cctactatag agaaaattta
1261 ttattaagtg actctccatc ttgtagagaa aatgattcca tacaatcaag gaaaaatgaa
1321 gaaagtcaag agattcagaa aaaactgtat acattagaag aacatcttag caatgagatg
1381 caagccaaag aggaactgga acagaagtgc aaatctgtta atactcgcct agaaaaaaca
1441 gcaaaggagc tagaagagga gattacctta cggaaaagtg tggaatcagc attaagacag
1501 ttagaaagag aaaaggcgct tcttcagcac aaaaatgcag aatatcagag gaaagctgat
1561 catgaagcag acaaaaaacg aaatttggaa aatgatgtta acagcttaaa agatcaactt
1621 gaagatttga aaaaaagaaa tcaaaactct caaatatcca ctgagaaagt gaatcaactc
1681 cagagacaac tggatgaaac caatgcttta ctgcgaacag agtctgatac tgcagcccgg
1741 ttaaggaaaa cccaggcaga aagttcaaaa cagattcagc agctggaatc taacaataga
1801 gatctacaag ataaaaactg cctgctggag actgccaagt taaaacttga aaaggaattt
1861 atcaatcttc agtcagctct agaatctgaa aggagggatc gaacccatgg atcagagata
1921 attaatgatt tacaaggtag aatatgtggc ctagaagaag atttaaagaa cggcaaaatc
1981 ttactagcga aagtagaact ggagaagaga caacttcagg agagatttac tgatttggaa
2041 aaggaaaaaa gcaacatgga aatagatatg acataccaac taaaagttat acagcagagc
2101 ctagaacaag aagaagctga acataaggcc acaaaggcac gactagcaga taaaaataag
2161 atctatgagt ccatcgaaga agccaaatca gaagccatga aagaaatgga gaagaagctc
2221 ttggaggaaa gaactttaaa acagaaagtg gagaacctat tgctagaagc tgagaaaaga
2281 tgttctctat tagactgtga cctcaaacag tcacagcaga aaataaatga gctccttaaa
2341 cagaaagatg tgctaaatga ggatgttaga aacctgacat taaaaataga gcaagaaact
2401 cagaagcgct gccttacaca aaatgacctg aagatgcaaa cacaacaggt taacacacta
2461 aaaatgtcag aaaagcagtt aaagcaagaa aataaccatc tcatggaaat gaaaatgaac
2521 ttggaaaaac aaaatgctga acttcgaaaa gaacgtcagg atgcagatgg gcaaatgaaa
2581 gagctccagg atcagctcga agcagaacag tatttctcaa ccctttataa aacacaagtt
2641 agggagctta aagaagaatg tgaagaaaag accaaacttg gtaaagaatt gcagcagaag
2701 aaacaggaat tacaggatga acgggactct ttggctgccc aactggagat caccttgacc
2761 aaagcagatt ctgagcaact ggctcgttca attgctgaag aacaatattc tgatttggaa
2821 aaagagaaga tcatgaaaga gctggagatc aaagagatga tggctagaca caaacaggaa
2881 cttacggaaa aagatgctac aattgcttct cttgaggaaa ctaataggac actaactagt
2941 gatgttgcca atcttgcaaa tgagaaagaa gaattaaata acaaattgaa agatgttcaa
3001 gagcaactgt caagattgaa agatgaagaa ataagcgcag cagctattaa agcacagttt
3061 gagaagcagc tattaacaga aagaacactc aaaactcaag ctgtgaataa gttggctgag
3121 atcatgaatc gaaaagaacc tgtcaagcgt ggtaatgaca cagatgtgcg gagaaaagag
3181 aaggagaata gaaagctaca tatggagctt aaatctgaac gtgagaaatt gacccagcag
3241 atgatcaagt atcagaaaga actgaatgaa atgcaggcac aaatagctga agagagccag
3301 attcgaattg aactgcagat gacattggac agtaaagaca gtgacattga gcagctgcgg
3361 tcacaactcc aagccttgca tattggtctg gatagttcca gtataggcag tggaccaggg
3421 gatgctgagg cagatgatgg gtttccagaa tcaagattag aaggatggct ttcattgcct
3481 gtacgaaaca acactaagaa atttggatgg gttaaaaagt atgtgattgt aagcagtaag
3541 aagattcttt tctatgacag tgaacaagat aaagaacaat ccaatcctta catggtttta
3601 gatatagaca agttatttca tgtccgacca gttacacaga cagatgtgta tagagcagat
3661 gctaaagaaa ttccaaggat attccagatt ctgtatgcca atgaaggaga aagtaagaag
3721 gaacaagaat ttccagtgga gccagttgga gaaaaatcta attatatttg ccacaaggga
3781 catgagttta ttcctactct ttatcatttc ccaaccaact gtgaggcttg tatgaagccc
3841 ctgtggcaca tgtttaagcc tcctcctgct ttggagtgcc gccgttgcca tattaagtgt
3901 cataaagatc atatggacaa aaaggaggag attatagcac cttgcaaagt atattatgat
3961 atttcaacgg caaagaatct gttattacta gcaaattcta cagaagagca gcagaagtgg
4021 gttagtcggt tggtgaaaaa gatacctaaa aagcccccag ctccagaccc ttttgcccga
4081 tcatctccta gaacttcaat gaagatacag caaaaccagt ctattagacg gccaagtcga
4141 cagcttgccc caaacaaacc tagctaactg ccttctatga aagcagtcat tattcaaggt
4201 gatcgtattc ttccagtgaa aacaagactg aaatatgatg accccatggt acccggatcc
4261 tcgaatcttt tgctttttac cctggaagaa atactcataa gccacctctg taatcggatc
4321 cccgggtacc gaaatactca taagccacct ctgtaatcgg atc
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