LOCUS D86061 1583 bp mRNA linear HUM 30-MAY-2003
DEFINITION Homo sapiens mRNA for KNP-Ia, complete cds.
ACCESSION D86061
VERSION D86061.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1583)
AUTHORS Shimizu,N.
TITLE Direct Submission
JOURNAL Submitted (17-JUN-1996) to the DDBJ/EMBL/GenBank databases.
Contact:Nobuyoshi Shimizu
Keio University School of Medicine, Department of Molecular
Biology; 35 Shinanomachi, Shinjuku-ku, Tokyo 160, Japan
REFERENCE 2
AUTHORS Nagamine,K., Kudoh,J., Minoshima,S., Kawasaki,K., Asakawa,S.,
Ito,F. and Shimizu,N.
TITLE Isolation of cDNA for a novel human protein KNP-1 that is
homologous to the E. coli SCRP-27A protein from the autoimmune
polyglandular disease type I (APECED) region of chromosome 21q22.3
JOURNAL Biochem. Biophys. Res. Commun. 225, 608-616 (1996)
COMMENT
FEATURES Location/Qualifiers
source 1..1583
/chromosome="21"
/clone_lib="fetal brain 5'-strech plus cDNA library
(CLONTECH)"
/db_xref="H-InvDB:HIT000101911"
/db_xref="taxon:9606"
/isolate="7 Caucasian fetuses, 20-26 weeks"
/map="21q22.3"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="brain"
CDS 18..824
/codon_start=1
/gene="KNP-I"
/note="alternative splicing: see also acc# D86062"
/product="KNP-Ia"
/protein_id="BAA12984.1"
/translation="MAAVRALVASRLAAASAFTSLSPGGRTPSQRAALHLSVPRPAAR
VALVLSGCGVYDGTEIHEASAILVHLSRGGAEVQIFAPDVPQMHVIDHTKGQPSEGES
RNVLTESARIARGKITDLANLSAANHDAAIFPGGFGAAKNLSTFAVDGKDCKVNKEVE
RVLKEFHQAGKPIGLCCIAPVLAAKVLRGVEVTVGHEQEEGGKWPYAGTAEAIKALGA
KHCVKEVVEAHVDQKNKVVTTPAFMCETALHYIHDGIGAMVRKVLELTGK"
exon 446..538
/note="alternatively spliced exon HC21EXc145"
regulatory 1565..1570
/regulatory_class="polyA_signal_sequence"
BASE COUNT 341 a 414 c 480 g 348 t
ORIGIN
1 ccgctgtcct caccgcaatg gcggctgtga gggccctggt ggcctcgagg ctcgctgcgg
61 catctgcatt cacgtccctg tcccccggcg gtcggacgcc ttcccagcgc gcagcccttc
121 acctctccgt gccgcgcccc gcggccaggg tcgcgctggt gctgtctgga tgcggagtct
181 acgatgggac cgagatccac gaggcctcgg cgatcctggt gcacctgagc cgtggagggg
241 ctgaagtcca gatctttgct cctgacgtcc ctcagatgca cgtgattgac cacaccaagg
301 ggcagccgtc cgaaggcgag agcaggaatg ttttgaccga gtctgcgagg atcgcccgtg
361 gcaaaatcac agacctggcc aacctcagtg cagccaacca tgatgctgcc atctttccag
421 gaggctttgg agcggctaaa aacctgagca cgtttgccgt ggacgggaaa gattgcaagg
481 tgaataaaga agtggagcgt gtcctgaagg agttccacca ggccgggaag cccatcggct
541 tgtgctgcat tgcacctgtc ctcgcggcca aggtgctcag aggcgtcgag gtgactgtgg
601 gccacgagca ggaggaaggt ggcaagtggc cttatgccgg gaccgcagag gccatcaagg
661 ccctgggtgc caagcactgc gtgaaggaag tggtcgaagc tcacgtggac cagaaaaaca
721 aggtggtcac gaccccagcc ttcatgtgcg agacggcact ccactacatc catgatggga
781 tcggagccat ggtgaggaag gtgctggaac tcactggaaa gtgacgcgca tggacggggc
841 ccagctaggc gccaggactt ggcctcaccc tctggctgag gagctgtcgg ctgctttcca
901 tccagctggg agtctggcag gccctttttt ttttttcttt gccgaaacct gcaggcgttc
961 tctctctaag gaggatgtgc tgcagtgcat gggggatgtt tcttcctggg tgtggctggg
1021 ctgctctcac atacagaggc cgaggggcca attcgttctc tgccacaggg acttgcctca
1081 ctgtgtccca aaaacaaatc gcagccagct tttccagaaa tagaaaattc tgccgtctga
1141 ggttttatac ttcaggttag ttagtttttg gaaggaagaa catttttagg tttgcaagcc
1201 tcctgatcag gaaaccagaa ataccacatt tatggaccat gaaaggttgg ttcttgactc
1261 tgaagggact tttgagttaa tcagcgtaag gggatttcta aagcaggcaa tccctgtagc
1321 cgcagagaat aaacgccttc ccaaaatggc aacttcccac agccacattt caaacctgct
1381 gagactgctg agtgaggaat ggcagtgagg tttcttcaat tagtctcagt tctcttaatt
1441 ttcaggaaga aagggaaatt gcagctcctc agcccccagg attgacctct ggggagtgat
1501 ggtagcgttg gtgccaggcc gtgggttcag gtgtggcaga agcttgcaga tgcgtccgaa
1561 gggaaataaa gtgtgttggc gtt
//