LOCUS D84296 7416 bp mRNA linear HUM 27-DEC-2006
DEFINITION Homo sapiens mRNA for TPRDIII, complete cds.
ACCESSION D84296
VERSION D84296.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7416)
AUTHORS Tsukahara,F.
TITLE Direct Submission
JOURNAL Submitted (03-APR-1996) to the DDBJ/EMBL/GenBank databases.
Contact:Fujiko Tsukahara
Tokyo Women's Medical College, Department of Pharmacology;
Kawada-cho 8-1, Shinjuku-ku, Tokyo 162, Japan
REFERENCE 2
AUTHORS Tsukahara,F.
TITLE Human mRNA for TPRDIII, complete cds.
JOURNAL Unpublished (1996)
REFERENCE 3
AUTHORS Tsukahara,F., Hattori,M., Muraki,T. and Sakaki,Y.
TITLE Identification and cloning of a novel cDNA belonging to
tetratricopeptide repeat gene family from Down syndrome-critical
region 21q22.2
JOURNAL J. Biochem. 120, 820-827 (1996)
COMMENT Sequence updated (24-Sep-1996) by: Fujiko Tsukahara
FEATURES Location/Qualifiers
source 1..7416
/chromosome="21"
/clone="TPRDIII"
/db_xref="H-InvDB:HIT000101873"
/db_xref="taxon:9606"
/map="21q22.2"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="fetal brain"
mRNA 1..7416
5'UTR 1..737
CDS 738..5885
/codon_start=1
/product="TPRDIII"
/protein_id="BAA12303.1"
/translation="MLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQ
GRTANKDPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKV
ADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEK
QFSKSSRAAHQDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQL
NLAMINYVLVVYGLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVY
LKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFP
PVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFND
KIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSL
EKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDD
RILQCIKQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRH
LIQENNRVKTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDF
SIMTFLWNEKYGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDE
FFDIMDSRCTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTSNNEII
TSSEDHSNRNSDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNPKQKCS
TLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFVVID
NCIALKKVASRLKKKRKKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVS
DSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPG
SEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLP
GLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGH
QIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVT
NIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYE
QIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKS
LKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDY
EESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIR
SWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLP
ESSGHDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPEATQL
TGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNSTE
LAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPV
TRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKY
HKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR"
3'UTR 5886..7416
regulatory 7394
/regulatory_class="polyA_signal_sequence"
BASE COUNT 2395 a 1461 c 1578 g 1982 t
ORIGIN
1 tacatttgga aagtcttact gacatgcaga aatagtacag aaaaacatac aaataggaat
61 gttattggct gggcatggtg gctcacacct gtaatcccag cactttggga ggccaaggcg
121 ggtggatcac aaggtcagga gatcgagacc atcgtggcta acatggtgaa accctgtgcc
181 tactaaaaat tcaaaaaatt agccaggtgt actggcatgt gctgtaatcc cagctacttg
241 ggaggctgag gcaggagaat cacttgaacc cgggagcaaa ggttgcagtg agccaagatc
301 acgccactgc actccagcct gggcgacaga gcgagactct gtctcaaaaa aaacaaaaga
361 atgctatgca taggtacaat gtcgaaatgt gcaagaaata cttcagaaat attaaaagta
421 gttattcctg ggtagttgtg attgtgactc tgggtgactt tttccctttg ttttattttt
481 ctgtattttc caaatttcct ataatggaca tatattatat ggattttttt taattaaaat
541 tatcttttga ctagataata tacatggaaa attcacaaag tacacatatg caagatataa
601 tacttttact ataaaagagt gaaaattttt aaatacttgt ttttcctttt agaaatgcac
661 tcggtgatgg aaagagagcc actattctga agaacacttg gccaaagggt cattatcgtt
721 attgtgatgc tctttctatg ctgggggaat atgactgggc cctgcaagca aacataaaag
781 ctcaaaaact ctgtaaaaat gaccctgagg gaatcaagga tctaattcag cagcatgtaa
841 agttacaaaa acaaatagaa gacctacaag gtcgaacagc aaataaggat ccaattaaag
901 ccttttatga aaacagggcc tacacaccta ggagtttatc agcacctata tttactactt
961 cacttaactt tgtggagaag gaaagagatt tcagaaaaat taatcacgaa atggccaacg
1021 gtggtaatca gaatctaaag gtggcggatg aggcgttgaa ggtagatgat tgtgactgtc
1081 atcctgaatt ttcaccacca tcaagtcagc ctccaaaaca taaaggaaaa caaaaatctc
1141 gaaacaatga atcagaaaag ttcagttcta gttcaccatt gactttacca gcagatttga
1201 agaacatctt ggagaaacag ttttctaaat cttccagagc tgcacaccag gattttgcta
1261 atataatgaa aatgctgaga agcttaattc aagatggcta tatggcctta ttggagcagc
1321 gttgccgcag cgctgcacag gcctttacag agttgctgaa cggtttagat cctcaaaaaa
1381 taaagcaatt gaacctggcc atgattaact atgttttggt cgtctatgga cttgccattt
1441 ctctccttgg aataggacag cctgaggaat tatctgaagc cgaaaaccag tttaagagga
1501 ttattgaaca ctaccccagt gagggccttg attgcttggc ctactgtgga attggaaaag
1561 tgtatttgaa aaaaaacaga tttctagaag ctctcaatca ctttgagaaa gcaagaacct
1621 tgatttatcg tcttcctgga gtgttaactt ggcccacgag taatgtgatt attgaagagt
1681 ctcagccaca aaaaataaag atgctgttag agaaatttgt tgaagaatgc aagttccctc
1741 cagtgccaga tgccatttgt tgctatcaga agtgccatgg atattctaag atccagatat
1801 acataactga tccagacttt aagggtttta tacgcatcag ctgttgccag tactgtaaaa
1861 tagaatttca catgaattgc tggaagaagt taaaaactac aacctttaat gataaaattg
1921 acaaggattt tctacaagga atatgtctta cccctgactg tgaaggtgtc atttctaaga
1981 ttatcatctt cagcagtggt ggtgaagtta aatgtgaatt tgaacacaag gtcataaaag
2041 aaaaggttcc tccaagacct attctgaaac agaaatgttc tagcctagag aaactaagac
2101 tgaaagaaga caaaaaattg aagagaaaga tccaaaaaaa agaagcaaaa aagttagcac
2161 aagaaagaat ggaggaggac ttaagagaaa gtaatccacc caaaaatgaa gagcagaaag
2221 aaactgtaga caatgttcag cgttgtcagt tccttgatga cagaattcta cagtgtataa
2281 agcagtatgc tgacaagatt aaatccggca tacagaatac agccatgctt ctcaaagaat
2341 tgctttcttg gaaagttttg agcacagaag actatacaac ctgtttttct agcagaaatt
2401 ttctaaatga agcagtggac tatgttattc gccacttgat tcaagaaaat aacagagtaa
2461 agacaagaat atttctgcat gttttgagtg agcttaaaga agtggagccc aaattagccg
2521 cctggatcca aaaacttaat agctttggct tagatgccac aggaactttc ttttctcgtt
2581 atggagcatc tcttaaactg cttgatttta gtatcatgac tttcctctgg aatgagaaat
2641 atggtcacaa actagactct atagaaggaa agcaacttga ttatttctct gagccagcat
2701 cattgaagga agcccgttgt ttaatatggc tgctagaaga acacagagac aagttcccag
2761 cattgcatag tgctttagat gaattctttg atataatgga cagccgctgt actgtgttaa
2821 ggaaacaaga tagtggtgaa gcaccgttta gttcaaccaa ggtgaaaaac aaaagcaaga
2881 aaaagaagcc aaaggattca aagcctatgt tagttgggtc tggaacaact tcagtaactt
2941 caaataatga gatcatcact tcaagtgaag accatagcaa tcgaaattca gattctgcag
3001 gcccatttgc agtgcctgac catcttcggc aagatgtaga agaattcgaa gctctctatg
3061 accaacacag taacgaatat gttgtccgca ataagaagct atgggacatg aacccaaaac
3121 aaaaatgttc aactctatat gattacttct ctcagttttt ggaggaacat ggtcccttgg
3181 acatgagtaa caagatgttc tctgcagaat atgagttttt cccagaagaa actcgacaga
3241 tactagaaaa agcaggaggt ttaaaacctt ttctcttggg atgccctcgt tttgttgtga
3301 ttgacaactg tattgcactg aagaaggttg catcacggct caagaaaaaa aggaagaaga
3361 aaaacattaa aacaaaagta gaagaaattt caaaagcagg ggagtatgta cgagttaaac
3421 tacaactgaa tccagctgct agggaattta aaccagatgt aaagtctaaa ccagtgtcag
3481 attcatcttc agcaccagct tttgaaaatg tgaaacccaa acctgtgtct gcaaattctc
3541 ccaagccagc ttgtgaagat gtgaaggcca aaccagtatc cgacaattct tctagacaag
3601 tttctgagga tgggcaaccc aaaggggtct cttctaattc tcctaaacca ggctctgagg
3661 atgcaaatta caagcgagtc tcctgtaatt cccccaaacc ggttcttgag gatgtgaaac
3721 caacttattg ggctcaatcc catttggtca caggatactg tacgtatctt cctttccaga
3781 gatttgatat cacccagaca ccgccagcat acataaacgt gttaccaggt ttgccccagt
3841 acaccagcat atatacaccc ttggccagcc tttctcctga atatcagcta ccaagatcag
3901 taccagtggt gccgtctttt gtagccaatg acagagcaga taaaaatgct gctgcctatt
3961 ttgagggtca tcatttgaat gctgagaatg ttgctggtca ccagattgcc tctgaaacac
4021 agatccttga gggctctttg ggaatatctg taaagtcaca ctgcagcaca ggtgatgctc
4081 atacagtcct gagtgagtct aacagaaatg atgagcactg tggaaattct aacaacaaat
4141 gtgaagtaat tccagaaagc accagtgcag taacaaacat tccacacgtg cagatggttg
4201 ccatacaggt atcttggaac ataatacacc aagaagtcaa tactgagcca tataatcctt
4261 ttgaggaacg acaaggggaa atttcacgga ttgaaaagga gcaccaagta ttacaagacc
4321 aacttcaaga agtgtatgaa aattatgagc agataaaact taagggctta gaagagacca
4381 gggacctgga agagaagttg aaaaggcact tagaagaaaa caagatctca aagacggaat
4441 tagattggtt ccttcaagat ttggaaagag aaattaaaaa atggcaacag gaaaaaaaag
4501 aaatccaaga aagactaaaa tcactgaaga agaaaattaa aaaggtttca aatgccagtg
4561 aaatgtatac ccagaaaaat gatggaaagg aaaaggaaca tgaattacat ctggatcagt
4621 cccttgaaat cagcaacaca cttacaaatg agaaaatgaa aatagaagag tatataaaga
4681 aagggaaaga ggattatgaa gagagtcatc agagagctgt ggctgcagag gtatccgtac
4741 ttgaaaactg gaaggagagt gaagtgtata agctacagat catggagtca caagcagaag
4801 cctttctgaa gaagctgggg ctgattagcc gtgatcctgc agcatatcct gacatggagt
4861 ctgatatacg ttcatgggaa ttgtttcttt ctaatgttac aaaagaaatt gagaaagcaa
4921 agtctcagtt tgaagaacaa attaaggcaa ttaaaaatgg ttctcggctc agtgaacttt
4981 ctaaagtgca gatttctgag ctttcatttc ctgcctgtaa cacggttcat cccgagttac
5041 tccctgagtc ttcaggccac gatggccaag ggcttgtgac ttctgcaagc gacgtgactg
5101 gaaaccacgc agcacttcac agggatccta gtgtgttctc tgctggtgat tccccagggg
5161 aggctccttc tgcgctgttg ccagggccac cccctggtca gcctgaagcc actcagctga
5221 cagggccaaa acgggctggc caggcagctc tgtcagaacg aagccctgtg gctgatcgga
5281 agcagcctgt tcctccagga cgtgctgcgc gttcaagcca gtctccaaaa aagccgttca
5341 atagtattat tgagcacctg tcagtggtat tcccatgtta caacagcact gagcttgctg
5401 gttttattaa aaaagtgcga agcaaaaaca agaactcact ctcaggattg agtattgatg
5461 aaattgtcca aagagtgaca gaacacattc tagatgaaca gaaaaagaaa aagccaaacc
5521 caggaaagga caagaggact tatgagccca gctctgccac ccccgtgacc aggtcctccc
5581 agggctcacc ctcggtggtt gttgcaccat cacccaaaac caaggggcag aaagcagaag
5641 atgtccctgt gaggattgca ctgggtgcaa gttcctgtga aatatgccac gaggtgttca
5701 aatcaaaaaa cgtgcgtgtg ctcaaatgtg ggcacaagta tcacaaaggg tgctttaagc
5761 agtggcttaa agggcagagc gcttgcccgg cctgccaggg tcgtgatctc ctgacagaag
5821 agtcaccttc tggaagaggc tggcccagtc agaatcagga gctgccttcc tgctcttcta
5881 ggtagtcaca cttcactaaa gtgtcatcca ccagtgtgtt gaatccgaag aatgacaatt
5941 ttctaccact ggtgtaaaaa acaaacattt gaagaccctt gtgcattgtg tgtcacaaag
6001 ctaaatacat ggaaatcgtt aatatcgctg atattaagta atttccccac tctgagtgaa
6061 tactttgatg attgccaaca gtggctaata aaatgacggc taccacactc atgggtcact
6121 ggggctgcgc agggctcttt gaggtgggtg gcttcttttg gaaagtacta tgaacgtctc
6181 gaagcagtat tctagtgata agaattctta acatagccaa gcgccccacg tttgttcccc
6241 acgtttgttc cccttttctg tttgaaaaac ctgttctggt agctccacaa gagagatgat
6301 actgactttt taaatttttt acaagagtct gtattcctga tatgcctata tttttcctca
6361 aagattctgc attttaagga tgggcataag caaactatat tttaataatt tatagttaat
6421 gttaaaatat tggctgattt agaccaaaag attcaaatct cctctttgtg aaatcccatc
6481 tgcatttgat tttttattat tttatgttcc cccgttagat tgttttaagt gtttgctttt
6541 catcttttat agatgtaatc tgattttcaa aaatcattaa cactttttaa ttagtatcga
6601 ctaagacttt ttccccctgg aatcgaggct gtgtgtccgt catcccagcc cccggttgga
6661 gcctgctctt tgaactccgc tgccttcctt agcagcttct gtcctcttct gtgagtcagt
6721 cagcgagtgc ttgggatccg catccagccg tgctgagcac acaacaggct gtgtgtggaa
6781 atggccacca ccattctcct tccccacccc accacaaaaa gagaagctgt gtctttagac
6841 aaccctgagg tatctgtgtt acaatcgttc tgtgtttgat atttgtgtaa agtatgcatg
6901 cagtcttgta ctgtgaccta agaacaaaac tgtaactgca ttagaaacca tgaaaaaatt
6961 agatattgtt ttgtgacttt tagacagtgg taaatataga accatgaatt ctggtcacat
7021 tccatttctc tccaacatga aggatcaaaa aatgtttttc aatgtgttct ttgttccact
7081 ggaaacttag agtcatgagt ttatgagctg atttggtcac cttcctctgc ctttgttcac
7141 tgtgagttct gatgtcttag tgacttagtt cttagaagct cacgccttag tttgaaacag
7201 attctccacg gtggtcccca aaacactgtc tgcatatcca taagaattga gcgctatggg
7261 tgttaacgtg catgaggatc agtttgcagc agcaagtaca aaaggagaag aggaacatcc
7321 gttgaatgag tgtgttttgt acataacttc agatacttgt gaacatgcct tatatttgtc
7381 caacaactgt cagaataaag aacattctaa aatgag
//