LOCUS HUMER60P 1741 bp mRNA linear HUM 06-FEB-1999
DEFINITION Homo sapiens mRNA for ER-60 protease, complete cds.
ACCESSION D83485
VERSION D83485.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1741)
AUTHORS Kito,M.
TITLE Direct Submission
JOURNAL Submitted (09-FEB-1996) to the DDBJ/EMBL/GenBank databases.
Contact:Makoto Kito
Kyoto University, Research Institute for Food Science; Gokasho,
Uji, Kyoto 611, Japan
REFERENCE 2
AUTHORS Urade,R., Oda,T., Ito,H., Moriyama,T., Utsumi,S. and Kito,M.
TITLE Functions of characteristic Cys-Gly-His-Cys (CGHC) and
Gln-Glu-Asp-Leu (QEDL) motifs of microsomal ER-60 protease
JOURNAL J. Biochem. 122, 834-842 (1997)
COMMENT
FEATURES Location/Qualifiers
source 1..1741
/cell_line="Chang liver"
/cell_type="epithelial cell"
/db_xref="H-InvDB:HIT000101800"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
5'UTR 1..22
CDS 23..1540
/product="ER-60 protease"
/protein_id="BAA11928.1"
/translation="MRLRRLALFPGVALLLAAGRLVAASDVLELTDDNFESRISDTGS
AGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPT
LKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFF
DDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDK
TVAYTEQKMTSGKIKKFIQENIFGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGS
NYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGE
KFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNN
ENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGF
PTIYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL"
sig_peptide 23..94
mat_peptide 95..1537
3'UTR 1541..1741
BASE COUNT 524 a 364 c 423 g 430 t
ORIGIN
1 ggcacgagcc cacctcgccg ccatgcgcct ccgccgccta gcgctgttcc cgggtgtggc
61 gctgcttctt gccgcgggcc gtctcgtcgc tgcctccgac gtgctagaac tcacggacga
121 caacttcgag agtcgcatct ccgacacggg ctctgcgggc ctcatgctcg tcgagttctt
181 cgccccctgg tgtggacact gcaagagact tgcacctgag tatgaagctg cagctaccag
241 attaaaagga atagtcccat tagcaaaggt tgattgcact gccaacacta acacctgtaa
301 taaatatgga gtcagtggat atccaaccct gaagatattt agagatggtg aagaagcagg
361 tgcttatgat ggacctagga ctgctgatgg aattgtcagc cacttgaaga agcaggcagg
421 accagcttca gtgcctctca ggactgagga agaatttaag aaattcatta gtgataaaga
481 tgcctctata gtaggttttt tcgatgattc attcagtgag gctcactccg agttcctaaa
541 agcagccagc aacttgaggg ataactaccg atttgcacat acgaatgttg agtctctggt
601 gaacgagtat gatgataatg gagagggtat catcttattt cgtccttcac atctcactaa
661 caagtttgag gacaagactg tggcatatac agagcaaaaa atgaccagtg gcaaaattaa
721 aaagtttatc caggaaaaca tttttggtat ctgccctcac atgacagaag acaataaaga
781 tttgatacag ggcaaggact tacttattgc ttactatgat gtggactatg aaaagaacgc
841 taaaggttcc aactactgga gaaacagggt aatgatggtg gcaaagaaat tcctggatgc
901 tgggcacaaa ctcaactttg ctgtagctag ccgcaaaacc tttagccatg aactttctga
961 ttttggcttg gagagcactg ctggagagat tcctgttgtt gctatcagaa ctgctaaagg
1021 agagaagttt gtcatgcagg aggagttctc gcgtgatggg aaggctctgg agaggttcct
1081 gcaggattac tttgatggca atctgaagag atacctgaag tctgaaccta tcccagagag
1141 caatgatggg cctgtgaagg tagtggtagc agagaatttt gatgaaatag tgaataatga
1201 aaataaagat gtgctgattg aattttatgc cccttggtgt ggtcactgta agaacctgga
1261 gcccaagtat aaagaacttg gcgagaagct cagcaaagac ccaaatatcg tcatagccaa
1321 gatggatgcc acagccaatg atgtgccttc tccatatgaa gtcagaggtt ttcctaccat
1381 atacttctct ccagccaaca agaagctaaa tccaaagaaa tatgaaggtg gccgtgaatt
1441 aagtgatttt attagctatc tacaaagaga agctacaaac ccccctgtaa ttcaagaaga
1501 aaaacccaag aagaagaaga aggcacagga ggatctctaa agcagtagcc aaacaccact
1561 ttgtaaaagg actcttccat cagagatggg aaaaccattg gggaggacta ggacccatat
1621 gggaattatt acctctcagg gccgagagga cagaatggat ataatctgaa tcctgttaaa
1681 ttttctctaa actgtttctt agctgcactg tttatggaaa taccaggacc agtttatgtt
1741 t
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