LOCUS HUMRASGAPA 2553 bp mRNA linear HUM 02-AUG-2002
DEFINITION Homo sapiens mRNA for rasGTPase activating protein, complete cds.
ACCESSION D78155
VERSION D78155.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2553)
AUTHORS Kobayashi,M.
TITLE Direct Submission
JOURNAL Submitted (31-OCT-1995) to the DDBJ/EMBL/GenBank databases.
Contact:Mariko Kobayashi
Mitsubishi Kasei Institute of Life Sciences; Division of
Pioneering Reseach, Machida, Tokyo 194, Japan
REFERENCE 2
AUTHORS Kobayashi,M., Masui,T., Kusuda,J., Kameoka,Y., Hashimoto,K. and
Iwashita,S.
TITLE Human rasGTPase-activating protein (human counterpart of GAP1m):
sequence of the cDNA, primary structure of the protein, production
and chromosomal localization
JOURNAL Gene 175, 173-177 (1996)
COMMENT
FEATURES Location/Qualifiers
source 1..2553
/cell_line="A431"
/cell_type="normal ectocervical epithelial epidermoid
carcinoma"
/chromosome="3"
/clone="A0r-B3h/L5"
/clone_lib="ET/TM"
/db_xref="H-InvDB:HIT000101741"
/db_xref="taxon:9606"
/map="3q21-q26"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="ectocervix"
CDS 1..2553
/codon_start=1
/function="rasGTPase activating activity"
/note="human counterpart of GAP1m"
/note="rasGAPIII-Hs"
/product="rasGTPase activating protein"
/protein_id="BAA11230.1"
/standard_name="rasGAP"
/translation="MAAAAPAAAAASSEAPAASATAEPEAGDQDSREVRVLQSLRGKI
CEAKNLLPYLGPHKMRDCFCTINLDQEEVYRTQVVEKSLSPFFSEEFYFEIPRTFQYL
SFYVYDKNVLQRDLRIGKVAIKKEDLCNHSGKETWFSLQPVDSNSEVQGKVHLELKLN
ELITENGTVCQQLVVHIKACHGLPLINGQSCDPYATVSLVGPSRNDQKKTKVKKKASN
PQFNEIFYFEVTRSSSYTRKSQFQVEEEDIEKLEIRIDLWNNGNLVQDVFLGEIKVPV
NVLRTDSSHQAWYLLQPRDNGNKSSKTDDLGSLRLNICYTEDYVLPSEYYGPLKTLLL
KSPDVQPISASAAYILSEICRDKNDAVLPLVRLLLHHDKLVPFATAVAELDLKDTQDA
NTIFRGNSLATRCLDEMMKIVGGHYLKVTLKPILDEICDSSKSCEIDPIKLKEGDNVE
NNKENLRYYVDKLFNTIVKSSMSCPTVMCDIFYSLRQMATQRFPNDPHVQYSAVSSFV
FLRFFAVAVVSPHTFHLRPHHPDAQTIRTLTLISKTIQTLGSWGSLSKSKSSFKETFM
CEFFKMFQEEGYIIAVKKFLDEISSTETKESSGTSEPVHLKEGEMYKRAQGRTRIGKK
NFKKRWFCLTSRELTYHKQPGSKDAIYTIPVKNILAVEKLEESSFNKKNMFQVIHTEK
PLYVQANNCVEANEWIDVLCRVSRCNQNRLSFYHPSVYLNGNWLCCQETGENTLGCKP
CTAGVPADIQIDIDEDRETERIYSLFTLSLLKLQKMEEACGTIAVYQGPQKEPDDYSN
FVIEDSVTTFKTIQQIKSIIEKLDEPHEKYRKKRSSSAKYGSKENPIVGKAS"
BASE COUNT 838 a 486 c 555 g 674 t
ORIGIN
1 atggcggcgg cggcgcctgc tgctgcggcg gcttcttccg aggcgccagc ggcgagtgcg
61 actgcagagc ccgaggccgg ggaccaggac agtcgcgagg ttcgagtgtt gcagagcctg
121 cggggcaaga tctgtgaagc aaaaaattta ttgccatatc ttggacccca caaaatgaga
181 gattgtttct gtaccataaa tttggaccag gaagaagttt atcgtaccca agttgtggaa
241 aaatctttaa gcccattttt cagtgaagaa ttttactttg agattccaag aactttccag
301 tatttgtctt tctatgttta tgataagaat gttttacaaa gagatctccg tataggaaaa
361 gtagccatca aaaaagaaga cttgtgtaat cacagtggca aagaaacttg gttttcatta
421 cagcctgttg actccaattc agaggttcag ggtaaagttc accttgaatt aaaactgaat
481 gaactgataa cggagaatgg aactgtatgc cagcagcttg ttgtacacat caaggcatgc
541 catgggttgc ctctcataaa tggccaaagc tgtgaccctt atgcaacagt ttctctagtg
601 ggcccttcta ggaatgacca aaagaagaca aaagtaaaga agaaagcaag caatccgcag
661 tttaatgaaa tcttttattt tgaggtaacc agatccagta gctacaccag aaagtcccag
721 ttccaggtag aagaggagga cattgaaaag ctagaaatca ggatcgactt gtggaacaat
781 ggaaacctag tccaagatgt tttcctaggt gagattaagg ttcctgtgaa cgtattaaga
841 actgattcct ctcatcaagc ctggtacttg ctacagccaa gagacaatgg aaacaagtca
901 tccaaaactg atgacctggg gtctcttcga ttaaatatat gttatacaga agactacgtg
961 cttccttcag agtactatgg tcctttgaaa actttgctgc taaaatcacc agatgttcaa
1021 ccaatatctg cctcagctgc ttacattttg agtgaaatat gtcgagataa aaatgatgct
1081 gttttgcccc ttgtacgact gctgctgcac catgataaac ttgttccttt tgccactgct
1141 gtggctgaat tagacttgaa ggatacacaa gatgcaaaca caatttttag aggaaattcc
1201 ctggctaccc gatgtctgga tgagatgatg aaaatagtgg gagggcacta cctgaaagta
1261 acattaaaac ctattcttga tgagatatgt gactcctcaa aatcctgtga aatcgatcct
1321 attaaattga aagagggaga taatgtagaa aataataagg agaatctgcg ctactatgta
1381 gacaagttat tcaatacaat tgtaaaatca agtatgagct gccccactgt aatgtgtgat
1441 atcttttatt ctctaaggca gatggctact cagagatttc ctaatgaccc tcatgttcag
1501 tattctgcag tgagcagctt tgtatttctt cgtttctttg ctgtagcggt agtatcacct
1561 catacttttc atttgcgacc tcatcatcca gatgcacaga caattagaac attaactctc
1621 atctcaaaaa ctatacaaac tttgggaagc tgggggagtc tgtccaaaag caagtcaagt
1681 ttcaaagaga cattcatgtg tgaatttttc aaaatgtttc aagaagaagg atatattata
1741 gcagttaaaa agttcttgga tgaaatttca tctactgaaa ctaaagagtc cagtggtacg
1801 agtgagcctg tgcacctgaa agaaggtgag atgtataaaa gagctcaagg aagaactcgg
1861 attggaaaaa agaattttaa gaaacgatgg ttctgcttaa caagcagaga gctcacctac
1921 cacaaacagc caggtagcaa agatgcaatc tacacaatcc cagtaaaaaa cattcttgct
1981 gtggaaaaac tggaagagag ctctttcaac aagaaaaaca tgttccaagt aatacatacg
2041 gagaaaccac tctatgtcca ggcaaataac tgtgtagaag ctaatgaatg gatagacgta
2101 ctctgcaggg tgagccgatg caatcaaaac aggctcagtt tttatcatcc ctctgtgtat
2161 ctaaacggaa attggctctg ctgtcaggag actggtgaaa acactctcgg ctgcaagcca
2221 tgtactgcag gtgtccctgc agacatccaa atagatattg atgaagacag agaaacagaa
2281 agaatttatt ccctttttac cctcagttta cttaagctgc agaagatgga agaggcttgt
2341 ggaactattg cagtctatca aggaccacag aaagagcctg atgattattc taactttgta
2401 atcgaggatt ctgtaacaac ctttaagaca attcagcaaa taaaaagcat aattgagaag
2461 ctggatgaac ctcatgaaaa atataggaag aaaagatcca gtagtgcaaa atatgggagc
2521 aaggaaaatc caattgttgg gaaagcatct tag
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