LOCUS HUMPLAA 4053 bp mRNA linear HUM 10-FEB-1999
DEFINITION Homo sapiens mRNA for placental leucine aminopeptidase, complete
cds.
ACCESSION D50810
VERSION D50810.1
KEYWORDS placental leucine aminopeptidase/oxytocinase; P-LAP; type II
membrane-spanning zinc-metallopeptidase family.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4053)
AUTHORS Rogi,T.
TITLE Direct Submission
JOURNAL Submitted (31-MAY-1995) to the DDBJ/EMBL/GenBank databases.
Contact:Tomohiro Rogi
Suntory Institute for Biomedical Research, Pharmaceutical
Research Laboratories I; 1-1-1 Wakayamadai, Shimamoto-cho,
Mishima-gun, Osaka 618, Japan
REFERENCE 2
AUTHORS Rogi,T.
JOURNAL Unpublished (1996)
REFERENCE 3 (bases 572 to 4053)
AUTHORS Rogi,T., Tsujimoto,M., Nakazato,H., Mizutani,S. and Tomoda,Y.
TITLE Human placental leucine aminopeptidase/oxytocinase. A new member
of type II membrane-spanning zinc metallopeptidase family
JOURNAL J. Biol. Chem. 271, 56-61 (1996)
COMMENT
FEATURES Location/Qualifiers
source 1..4053
/db_xref="H-InvDB:HIT000101638"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="placenta"
CDS 715..3549
/codon_start=1
/product="placental leucine aminopeptidase"
/protein_id="BAA09436.1"
/translation="MNRSSGLRNSATGYRQSPDGACSVPSARTMVVCAFVIVVAVSVI
MVIYLLPRCTFTKEGCHKKNQSIGLIQPFATNGKLFPWAQIRLPTAVVPLRYELSLHP
NLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTFMSAVSSQEKQAEILEYAYHG
QIAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFSYTDESNEKKYFAATQFEPLAA
RSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDDGLVQDEFSESVKMSTY
LVAFIVGEMKNLSQDVNGTLVSIYAVPEKIGQVHYALETTVKLLEFFQNYFEIQYPLK
KLDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAHELAHQWFGN
LVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSSYEDFLDARFKTMKKDSLNSSHPIS
SSVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSEDVFQHAVVLYLHNHSYASIQSDDL
WDSFNEVTNQTLDVKRMMKTWTLQKGFPLVTVQKKGKELFIQQERFFLNMKPEIQPSD
TSYLWHIPLSYVTEGRNYSKYQSVSLLDKKSGVINLTEEVLWVKVNINMNGYYIVHYA
DDDWEALIHQLKINPYVLSDKDRANLINNIFELAGLGKVPLKRAFDLINYLGNENHTA
PITEALFQTDLIYNLLEKLGYMDLASRLVTRVFKLLQNQIQQQTWTDEGTPSMRELRS
ALLEFACTHNLGNCSTTAMKLFDDWMASNGTQSLPTDVMTTVFKVGAKTDKGWSFLLG
KYISIGSEAEKNQILEALASSEDVRKLYWLMKSSLNGDNFRTQKLSFIIRTVGRHFPG
HLLAWDLVKENWNKLVQKFPLGSYTIQNIVAGSTYLFSTKTHLSEVQAFFENQSEATF
RLRCVQEALEVIQLNIQWMEKNLKSLTWWL"
BASE COUNT 1122 a 877 c 936 g 1118 t
ORIGIN
1 gtttatttat ggtctgtttc tggaatgtcc gctcctggga ctgggaccat gattttctgg
61 cgcagtgcgg gtgtctcggc gtccgggatc gggcgggtcg cagtagggct ccacatttgt
121 tgagtgactg aacaccgttc ccggccgggg agagcgccgc agccgggtcc acttcaggta
181 ggggctgggc tttcccggcc ccgcctaggc cccgccccca gcgcgaaccc gctcccacct
241 cgcctgtccg cggagcagca gggggtttga ctgtgctttt ccctcttgct tccctcgctc
301 tttctgcagc tgccacgaaa acccggaacg gcggagcggc gccgcccctc gcggcacctc
361 cctggcagcc cttggaggcc gcgctgggca tgctcagtca gctgggccgc ctcagctctc
421 ggagtaggaa gctcgggcgc tccggctgta aggagccgcg gcggggggaa aatggagccc
481 ttcaccaatg atcggcttca gctccccagg aatatgattg aaaacagcat gtttgaggaa
541 gaaccagatg tggtggattt agccaaagag ccttgtttac atcctctaga gcctgatgag
601 gtggaatatg agccccgggg ttcccgactg ctggtgcggg gtcttggtga gcatgagatg
661 gaggaggatg aagaggatta tgagtcatca gcaaagctgc tgggcatgtc cttcatgaat
721 agaagctcag gccttcggaa cagtgcaact ggttacaggc agagcccaga tggggcttgt
781 tcagtaccct ctgcaaggac catggtggtc tgtgcttttg tcatcgtggt tgctgtttct
841 gtaatcatgg tgatttactt actgcccaga tgtaccttta ccaaagaagg ctgccataaa
901 aaaaaccagt caattggact aattcagcca tttgcaacaa atgggaaatt gtttccatgg
961 gcacagatca ggcttcccac tgccgtggtg ccactacgct atgaactcag cctacacccg
1021 aacctaacct cgatgacatt caggggttct gtgacaattt cagttcaggc tcttcaggtc
1081 acatggaata tcattcttca tagcacaggt cataatattt caagagtgac ctttatgtca
1141 gcagtttcaa gccaagaaaa acaagctgag atcctggaat atgcatatca tggacagatc
1201 gccattgttg cccccgaagc ccttctagca gggcacaatt atacgttgaa gatagagtac
1261 tcggcaaata tatctagttc ttattatggg ttttatggct tctcctacac agatgaaagt
1321 aatgagaaaa agtactttgc agcaactcag tttgaacccc tggcagcaag atctgctttt
1381 ccttgttttg atgaaccagc atttaaagcc acttttatca tcaagatcat aagggatgag
1441 caatacaccg ctttatcaaa tatgcctaag aagtcatcag tcgttctaga tgatggactt
1501 gttcaggatg agttttctga gagtgtgaag atgagcactt acttggttgc tttcattgtg
1561 ggagagatga agaacctgag tcaggacgta aatggaaccc tggtttctat atatgctgta
1621 ccagaaaaga ttggtcaagt tcattatgcc ttggaaacaa ctgtgaagct tcttgagttt
1681 tttcaaaact actttgaaat tcagtaccca cttaagaaat tggatttggt ggctattcct
1741 gactttgaag caggagcaat ggaaaattgg ggtttgctca ccttccgaga ggagacactt
1801 ctgtatgaca gtaacacttc ttcaatggcg gatagaaagc tggtgactaa aatcattgct
1861 catgagctgg cccaccagtg gtttggcaat ctggtaacaa tgaagtggtg gaatgaccta
1921 tggctaaatg aaggttttgc cactttcatg gagtatttct ctttggaaaa aatattcaaa
1981 gagctttcta gttatgaaga tttcttagat gctcgattta aaaccatgaa gaaagattcc
2041 ttaaattcat ctcatccaat atcatcatct gttcagtctt cagaacaaat tgaagaaatg
2101 tttgattctc tttcctattt taagggatct tctctcttgt tgatgttgaa aacttacctt
2161 agtgaagatg tgtttcaaca tgctgttgtc ctttacctgc ataatcacag ctatgcatct
2221 attcaaagtg atgatctgtg ggatagtttt aatgaggtca caaaccaaac actagatgta
2281 aagagaatga tgaaaacctg gaccctgcag aaaggatttc ctttagtgac tgttcaaaag
2341 aaaggaaagg aactttttat acaacaagag agattctttt taaatatgaa gcctgaaatt
2401 cagccttcag atacaagcta cctgtggcat attccactat cctatgtcac tgaaggaaga
2461 aattattcaa aatatcaatc ggtatcatta ctggataaga aatcaggtgt catcaatctt
2521 acagaagaag tgctgtgggt caaagtgaat ataaacatga atggttatta tattgtacac
2581 tatgcagatg atgattggga agcactaatc catcagttga aaataaatcc ttatgttctg
2641 agtgacaaag accgagccaa ccttatcaac aacatctttg aacttgcagg cctaggcaag
2701 gtacctctca agagggcctt tgatttgatt aattatcttg gaaatgagaa ccatactgca
2761 cccatcaccg aagccctgtt tcagacagac ctcatctata acctccttga aaaactggga
2821 tacatggatc tggcctcaag actggtgact agggtattta aattacttca aaaccaaatt
2881 caacaacaaa cttggactga tgagggcact ccatctatgc gagagcttcg gtcagccctg
2941 ctagagtttg cttgcaccca caacctgggg aactgctcta ctactgccat gaaactgttt
3001 gatgactgga tggcatccaa tggaactcaa agcctaccta ctgatgtcat gacaactgtg
3061 ttcaaagttg gagcaaaaac tgacaaaggc tggtcattcc ttttgggcaa atacatttct
3121 ataggctctg aagcagagaa gaaccaaata ctagaagcac ttgccagctc agaggatgtg
3181 cggaagcttt actggttaat gaaaagtagc ctgaatggag ataacttccg aacacagaag
3241 ctgtctttta tcattagaac agtgggtcga cattttcctg gacacttact ggcatgggat
3301 ttggtcaaag agaactggaa taagcttgta cagaagttcc ctctggggtc ctataccata
3361 caaaatattg ttgctggatc aacttacctg ttttcaacaa agacacattt atctgaggtt
3421 caggcattct ttgaaaatca gtcagaggca accttccggc ttcgttgtgt ccaggaggct
3481 ttggaagtca ttcagttgaa tatccagtgg atggagaaga acctcaaaag tctcacatgg
3541 tggctgtagc atgcacaacc gcacctcatt ttgttgccca ttcagagagc ttgtaagctt
3601 gggctctgcc gcttttgcaa aagccaaggt aaagccagga tcgctgccaa gttgtttgca
3661 ctctttggag ttctagttag ctcagggcct gactgtattt ttcatccatc ttttctgaag
3721 tgtctttggg cagtatgtag ttatttatta caaaattata ttcacctaaa tgccaaccat
3781 ctacaaaaac aatgagtaat ttttctactt tgaagataca cagatgggga cccaaaaccc
3841 tgttttggaa ttctgttcta ttcctcagta tccagaaagt tactgacaca gtaaaacaag
3901 gaaagttcta ccctaagagc cgccatcact tcaggccgct ggtttgtcag ccatctgttg
3961 cttcttattg atagatggca ttggaatgtg gtacaaagtt agctctgaag aatatggtaa
4021 cgaagacaat aaagcatgca ctgtaagaac tga
//