LOCUS D50017 17087 bp DNA linear HUM 30-OCT-2007
DEFINITION Homo sapiens PDGFRA gene for alpha-platelet-derived growth factor
receptor, complete cds.
ACCESSION D50017 D50001-D50016
VERSION D50017.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 17087)
AUTHORS Kawagishi,J.
TITLE Direct Submission
JOURNAL Submitted (03-APR-1995) to the DDBJ/EMBL/GenBank databases.
Contact:Jun Kawagishi
Tohoku University, Gene Research Center; 1-1
Tsutsumidouri-Amamiyamachi, Aobaku, Sendai, Miyagi 981, Japan
REFERENCE 2
AUTHORS Kawagishi,J.
TITLE Homo sapiens DNA for alpha-platelet-derived growth factor receptor
JOURNAL Unpublished (1996)
REFERENCE 3
AUTHORS Kawagishi,J. and Ku,T.
TITLE Structure, organization, and transcription units of the human
alpha-platelet-derived growth factor receptor gene, PDGFRA
JOURNAL Genomics 30, 224-232 (1995)
REFERENCE 4
AUTHORS Kumabe,T., Sohma,Y., Kayama,T., Yoshimoto,T. and Yamamoto,T.
TITLE Amplification of alpha-platelet-derived growth factor receptor
gene lacking an exon coding for a portion of the extracellular
region in a primary brain tumor of glial origin
JOURNAL Oncogene 7, 627-633 (1992)
COMMENT
FEATURES Location/Qualifiers
source 1..17087
/chromosome="4"
/db_xref="taxon:9606"
/map="4q11-q13"
/mol_type="genomic DNA"
/organism="Homo sapiens"
/tissue_type="blood"
regulatory 99..105
/note="GCF (GC factor) binding site"
/regulatory_class="other"
regulatory 319..324
/note="GATA motif"
/regulatory_class="other"
regulatory 345..350
/note="GATA motif"
/regulatory_class="other"
regulatory 373..378
/note="GATA motif"
/regulatory_class="other"
regulatory 539..543
/regulatory_class="CAAT_signal"
regulatory 708..715
/note="Oct-1 and Oct-2 like motif"
/regulatory_class="other"
exon 900..1280
/gene="PDGFRA"
/number=1
/product="alpha-platelet-derived growth factor receptor"
intron 1281..>1768
/number=1
gap 1769..1868
/estimated_length=unknown
intron <1869..2136
/number=1
exon 2137..2197
/gene="PDGFRA"
/number=2
/product="alpha-platelet-derived growth factor receptor"
CDS join(2149..2197,3209..3526,3894..4154,4459..4589,
5271..5442,5534..5723,8602..8717,10362..10488,
11505..11698,11879..11973,12189..12321,12607..12711,
13040..13150,13606..13759,14038..14204,14468..14583,
14865..14987,15543..15654,15877..15976,16087..16192,
16409..16650,16886..17033)
/codon_start=1
/gene="PDGFRA"
/product="alpha-platelet-derived growth factor receptor"
/protein_id="BAA08742.1"
/translation="MGTSHPAFLVLGCLLTGLSLILCQLSLPSILPNENEKVVQLNSS
FSLRCFGESEVSWQYPMSEEESSDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTCYY
NHTQTEENELEGRHIYIYVPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVT
LHNSEGVVPASYDSRQGFNGTFTVGPYICEATVKGKKFQTIPFNVYALKATSELDLEM
EALKTVYKSGETIVVTCAVFNNEVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLT
VPEATVKDSGDYECAARQATREVKEMKKVTISVHEKGFIEIKPTFSQLEAVNLHEVKH
FVVEVRAYPPPRISWLKNNLTLIENLTEITTDVEKIQEIRYRSKLKLIRAKEEDSGHY
TIVAQNEDAVKSYTFELLTQVPSSILDLVDDHHGSTGGQTVRCTAEGTPLPDIEWMIC
KDIKKCNNETSWTILANNVSNIITEIHSRDRSTVEGRVTFAKVEETIAVRCLAKNLLG
AENRELKLVAPTLRSELTVAAAVLVLLVIVIISLIVLVVIWKQKPRYEIRWRVIESIS
PDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKV
AVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDL
VNYLHKNRDSFLSHHPEKPKKELDIFGLNPADESTRSYVILSFENNGDYMDMKQADTT
QYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLLSDDNSEGLTLLDLLSF
TYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTF
LPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYR
MAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKS
DHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYIIPLPDIDPVPE
EEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSF
L"
intron 2198..>2904
/number=2
gap 2905..3004
/estimated_length=unknown
intron <3005..3208
/number=2
exon 3209..3526
/gene="PDGFRA"
/number=3
/product="alpha-platelet-derived growth factor receptor"
intron 3527..>3644
/number=3
gap 3645..3744
/estimated_length=unknown
intron <3745..3893
/number=3
exon 3894..4154
/gene="PDGFRA"
/number=4
/product="alpha-platelet-derived growth factor receptor"
intron 4155..>4295
/number=4
gap 4296..4395
/estimated_length=unknown
intron <4396..4458
/number=4
exon 4459..4589
/gene="PDGFRA"
/number=5
/product="alpha-platelet-derived growth factor receptor"
intron 4590..>4889
/number=5
gap 4890..4989
/estimated_length=unknown
intron <4990..5270
/number=5
exon 5271..5442
/gene="PDGFRA"
/number=6
/product="alpha-platelet-derived growth factor receptor"
intron 5443..5533
/number=6
exon 5534..5723
/gene="PDGFRA"
/number=7
/product="alpha-platelet-derived growth factor receptor"
intron 5724..8601
/number=7
repeat_region 7478..7505
/note="(ac)14"
/rpt_type=direct
repeat_region 7632..7921
/rpt_family="Alu"
/rpt_type=inverted
exon 8602..8717
/gene="PDGFRA"
/number=8
/product="alpha-platelet-derived growth factor receptor"
intron 8718..10361
/number=8
exon 10362..10488
/gene="PDGFRA"
/number=9
/product="alpha-platelet-derived growth factor receptor"
intron 10489..11504
/number=9
exon 11505..11698
/gene="PDGFRA"
/number=10
/product="alpha-platelet-derived growth factor receptor"
intron 11699..>11749
/number=10
gap 11750..11849
/estimated_length=unknown
intron <11850..11878
/number=10
exon 11879..11973
/gene="PDGFRA"
/number=11
/product="alpha-platelet-derived growth factor receptor"
intron 11974..12188
/number=11
exon 12189..12321
/gene="PDGFRA"
/number=12
/product="alpha-platelet-derived growth factor receptor"
intron 12322..>12468
/number=12
gap 12469..12568
/estimated_length=unknown
intron <12569..12606
/number=12
exon 12607..12711
/gene="PDGFRA"
/number=13
/product="alpha-platelet-derived growth factor receptor"
intron 12712..>12738
/number=13
gap 12739..12838
/estimated_length=unknown
intron <12839..13039
/number=13
exon 13040..13150
/gene="PDGFRA"
/number=14
/product="alpha-platelet-derived growth factor receptor"
intron 13151..>13218
/number=14
gap 13220..13319
/estimated_length=unknown
intron <13320..13605
/number=14
exon 13606..13759
/gene="PDGFRA"
/number=15
/product="alpha-platelet-derived growth factor receptor"
intron 13760..>13878
/number=15
gap 13879..13978
/estimated_length=unknown
intron <13979..14037
/number=15
exon 14038..14204
/gene="PDGFRA"
/number=16
/product="alpha-platelet-derived growth factor receptor"
intron 14205..>14311
/number=16
gap 14312..14411
/estimated_length=unknown
intron <14412..14467
/number=16
exon 14468..14583
/gene="PDGFRA"
/number=17
/product="alpha-platelet-derived growth factor receptor"
intron 14584..>14672
/number=17
gap 14673..14772
/estimated_length=unknown
intron <14773..14864
/number=17
exon 14865..14987
/gene="PDGFRA"
/number=18
/product="alpha-platelet-derived growth factor receptor"
intron 14988..>15044
/number=18
gap 15045..15144
/estimated_length=unknown
intron <15145..15542
/number=18
exon 15543..15654
/gene="PDGFRA"
/number=19
/product="alpha-platelet-derived growth factor receptor"
intron 15655..>15669
/number=19
gap 15670..15769
/estimated_length=unknown
intron <15770..15876
/number=19
exon 15877..15976
/gene="PDGFRA"
/number=20
/product="alpha-platelet-derived growth factor receptor"
intron 15977..16086
/number=20
exon 16087..16192
/gene="PDGFRA"
/number=21
/product="alpha-platelet-derived growth factor receptor"
intron 16193..>16254
/number=21
gap 16255..16354
/estimated_length=unknown
intron <16355..16408
/number=21
exon 16409..16650
/gene="PDGFRA"
/number=22
/product="alpha-platelet-derived growth factor receptor"
intron 16651..>16705
/number=22
gap 16706..16805
/estimated_length=unknown
intron <16806..16885
/number=22
exon 16886..>17087
/gene="PDGFRA"
/number=23
/product="alpha-platelet-derived growth factor receptor"
BASE COUNT 4025 a 3479 c 3421 g 4562 t
ORIGIN
1 gaattcaaaa atcagagagc gatgaaggtg aacgcgctcc cctcccccgc tgtcgctggg
61 aagccccact ctgcccaggt ctggttcctg gagcatcagc gccccctttc cctcgccggc
121 aggatcgttt cctcccgaca ctggcctctc gccttgggcg cagggtttgg ggctcagctg
181 tcaattccaa ggaattcgta gggttcgacc cacgcggcgg gagggaacgg agggagaatc
241 aaaaggcatc ctcccccacg acgcggaggc ggtggtacga ttcctcaaac gcccaagctt
301 gagctttttt tgtatgcgag atagaagcca gggcaacctc gcccagataa ccccgaaaac
361 aaaggcacga ccagataagt gacttcaagg gagtaaaggt cgttctatcg gagaacgttc
421 caaacctaca cagaccctct tttctttgta ccgtatttca gaccacccag tcttgtacac
481 acacacacac cacacaaaac aaaaacccat cattgtcata ttggactcaa cagtttgccc
541 aatcctatta aataactagc aactatatag cccttcccct aaaagacccc tagttcaaaa
601 cggcgcaacc gcttggagat ttctcccgag ggccctattt ctcgttgggc cgagtttgta
661 gaagggacat ttcttgattc tagatttata ttctctctgg gtattaaatg caattttgta
721 tgttcctttt cttcttttca aagagaatac aaaactatag cagtctaaga aaataacccc
781 aaaatgggga ggcaaactca ttctggaaat gatgggctgt ttgtagtttc acaaaacctc
841 tttcccggca gagcaccaac acctccccct tccaccaccc cccatcccat ctggtctgct
901 tctccccgcc ccccagttgt tgtcgaagtc tgggggttgg gactggaccc cctgattgcg
961 taagagcaaa aagcgaaggc gcaatctgga cactgggaga ttcggagcgc agggagtttg
1021 agagaaactt ttattttgaa gagaccaagg ttgagggggg gcttatttcc tgacagctat
1081 ttacttagag caaatgatta gttttagaag gatggactat aacattgaat caattacaaa
1141 acgcggtttt tgagcccatt actgttggag ctacagggag agaaacagag gaggagactg
1201 caagagatca ttggaggccg tgggcacgct ctttactcca tgtgtgggac attcattgcg
1261 gaataacatc ggaggagaag gtaagggaaa agaaaaaatg attttttgtt tataagggaa
1321 gtccctgatc agactctggg actggagaaa gcgaagtaac ttcaaacttt gggcgacaag
1381 aaaaaaaaaa aggagctgga ttccagttgt gtgtccagag agtaattttt ttttttcgga
1441 ataaacttca cttggggacg ggtgggagat aaccatagag ttagaaagtc taggtatttt
1501 ttttcaaaca cacattttcc agacctattt ttaaaaacaa tgtttttcta acaaccctat
1561 ggcctcccaa agaaattgtt taggcttaca tttttgaggt ttcttttggg agtgggggtg
1621 gtgttcgtga atactgggcc gaacaccaag gaactggggg tggaggcaga ggtgtttgcc
1681 ctcttcttgg cagtgggtcc tggaaggcga caggttttaa atgagtgttt tcattcctcg
1741 cctgcggttt ggcgggacag cgctgcagnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1861 nnnnnnnntt aatataaatg gtttaaagga ccattgaaaa ctgcatgcaa tcacagaagg
1921 ttttggcttc aggcagctcc cgccatgatc ttggggcccc attgattctt tcatctttca
1981 ggcgtcttac tgtttgaacc ttgaatttta acctgggaca tgtttgacta aaatgatgct
2041 gttaatattt tctgttgtgc aaaacacaaa gagaactagg ctccagggtt gtttctattt
2101 gctaatgctg tttctgttga cttttgactt ttctagtttc ccagagctat ggggacttcc
2161 catccggcgt tcctggtctt aggctgtctt ctcacaggta cggagcccag tcctctctga
2221 gttccttgtt tgggtgtctt gtttttttaa gctttgtgct gcatgggttt tttaccagta
2281 ctctgcatac acagtccaaa agagtgaaaa gaaatagaaa actataggac gttatccaga
2341 atgaccacaa accttcagtt ccctttgctg tattgcactt actccatttc aaaaggaatg
2401 ctctccagtg gcagttttag tacatatata atgttggcat tgaaatgttg ttagtaataa
2461 tgtctaaatt tacttactac tctcttcctt ttcctaggac aaggcttcta ttagagctgg
2521 attagataaa ttcaggaatg gtcagctgtg ggaggtggca catctgttgt cccagcccct
2581 tgagcagctg aggtgggatg atcccttaag gccaggagtt caaggttgca gtgcactgtg
2641 ttatgcctgt gactagccac cacactccag caacatagca agacctcatt taaaaaaaat
2701 gttcaaagga aataaataat agaaaattct tgcccaagaa atcatacttg tcttaaatca
2761 taactctctt gaggaaagat gcttacattg cttctaaatc tcagagtcac ctttatcttc
2821 tctaggaatc aaattgatag atgaatgttt ggctcttgga aaatcttaaa aactttccca
2881 ccaaaaggat ccgttgacct gcagnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3001 nnnnggtgga gctatttgga acatttgctg ctctcagcag atgcagtggc tgttataatg
3061 ggggagcttt catgggcatc caggctaacg gatttttgtg tagaaatggt cattgttcat
3121 ctaagctgct actgttgctt ctctcagttg tcgggatgag actgtccttt ctgactgcat
3181 cctattcaga gcgtgcttcc ttttgcaggg ctgagcctaa tcctctgcca gctttcatta
3241 ccctctatcc ttccaaatga aaatgaaaag gttgtgcagc tgaattcatc cttttctctg
3301 agatgctttg gggagagtga agtgagctgg cagtacccca tgtctgaaga agagagctcc
3361 gatgtggaaa tcagaaatga agaaaacaac agcggccttt ttgtgacggt cttggaagtg
3421 agcagtgcct cggcggccca cacagggttg tacacttgct attacaacca cactcagaca
3481 gaagagaatg agcttgaagg caggcacatt tacatctatg tgccaggtga gttggctggg
3541 tctccaggac caagcttctt ctcttcctgt ctctcctgtt aaatgtacta aggttttaaa
3601 catatatata aataattaat atttattgcg ggaaggtttg aaaannnnnn nnnnnnnnnn
3661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3721 nnnnnnnnnn nnnnnnnnnn nnnntacaat gccagtgggc aattcttctg atatatgtgt
3781 aaaggtgaac ttcataccta atatcaataa tgccagtggg atagtttttc tggatttatg
3841 tgtaaaggtg aaattaatgt ctaatagagt cttcattctt ttttaaacca cagacccaga
3901 tgtagccttt gtacctctag gaatgacgga ttatttagtc atcgtggagg atgatgattc
3961 tgccattata ccttgtcgca caactgatcc cgagactcct gtaaccttac acaacagtga
4021 gggggtggta cctgcctcct acgacagcag acagggcttt aatgggacct tcactgtagg
4081 gccctatatc tgtgaggcca ccgtcaaagg aaagaagttc cagaccatcc catttaatgt
4141 ttatgcttta aaaggtactt gtatcatctc cttcttcttt aaataagagt aacaggcaaa
4201 atcataaggt gcgtgtagga tttttttttt tttttaaatc accatcactg gtgatcctaa
4261 attctgattt ggggatttag gaccccagct aatacnnnnn nnnnnnnnnn nnnnnnnnnn
4321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
4381 nnnnnnnnnn nnnnnacctt tataagatcc tggctatcct gtggattttt aggcccttgt
4441 atttgttctt ttttatagca acatcagagc tggatctaga aatggaagct cttaaaaccg
4501 tgtataagtc aggggaaacg attgtggtca cctgtgctgt ttttaacaat gaggtggttg
4561 accttcaatg gacttaccct ggagaagtgg taggtaccct caaaacgtgc aatggcttgg
4621 agcagagcaa cagggctcag aagacctgca tttgagctcg gtctgtcact gatgggcaca
4681 tcactgagtt tctctagacc ttagcttccc acctctggga tgaacacatt tgattaaatg
4741 gcctttagga ctccttgatc aatgggagag tttgaaatga tagttcctgg accaggccct
4801 tcagaataca taaagagtgt gccgtaagcc ttctttttca gaagtcagac agaaatagga
4861 aggttctctg gctacaagat atcaaccaan nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
4921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
4981 nnnnnnnnna tctcatgatt ttctaagcag ctagctttta ttctttaggt tttatctttt
5041 agagcagttt taggtttaca ccaaaattga gaggtacaga gatttcccat gtgttcccta
5101 cacccacaca tgtgtagcct cccaccttgt caacatccct accatccatt tgttataact
5161 gctgaacctc cattgacaca tccatatcat ccagagtcca tagtttatct tagagttcac
5221 tcctaggagc gagcttttta aaagtcggtt ttcttcccct tttgctgtag aaaggcaaag
5281 gcatcacaat gctggaagaa atcaaagtcc catccatcaa attggtgtac actttgacgg
5341 tccccgaggc cacggtgaaa gacagtggag attacgaatg tgctgcccgc caggctacca
5401 gggaggtcaa agaaatgaag aaagtcacta tttctgtcca tggtacattc cgctttctaa
5461 aatgtcagtt gtccatgctg ctcgggatcc atatgtggta atcattattt aatggaaact
5521 cttccctgta cagagaaagg tttcattgaa atcaaaccca ccttcagcca gttggaagct
5581 gtcaacctgc atgaagtcaa acattttgtt gtagaggtgc gggcctaccc acctcccagg
5641 atatcctggc tgaaaaacaa tctgactctg attgaaaatc tcactgagat caccactgat
5701 gtggaaaaga ttcaggaaat aaggtaaaga aactctctgc ccaagtatgc ctttttttag
5761 tgtgcatcag aggcggactg aggtttgtgt gtgtcttaca acccagaccc aaagtcagtc
5821 tagaaaatgt aacaatctga gttaagagat gcttgaaatc acatcccttt aatgataaca
5881 ttgcaaagtg gtattagtat gctggtaagt atttaatgag aagatgagaa gaaagaacta
5941 aaagctctgg cccctgggga aagacaggtc actggattca gctagggtgg aagaaaggaa
6001 gtaaaattgg actcaccagg attgaataga ttgaatatat tccctgatgt tcatcatcca
6061 tatcgcaagt agacagatta tggtgattac acccatgagg cagttatcac atcaccttac
6121 gtgaaagtta acgtcatagg cttaatctgg aacccatttg ccctaattga ggactccaca
6181 ggaaagaaga gtagagcctg gctaatcagg agagagatgt gcagtgagtt gcttggatcc
6241 ctacctttta atcagaatgg tagattgctc tcatctctta attggtggtg gagttttgaa
6301 tgagtcaccc ctcagccaca gtttcctcat ctacaatgta ggataaacaa taccttatgt
6361 ccttcaaggc aaggaattgg atcagatgat atcatgaggc ctcttaaggt tttaagctgt
6421 gattagaacc caagagtcag aagatacatc tcacagcacc cagctaacag ccctatactt
6481 tgtcagaaat catctcagaa agacaaagtc agtcctgtat ttcaagcctt caggaggaag
6541 aacagagcct ttctcatcag tccattcacc tcaggatttg cttcttcttt gtgaactaaa
6601 tccacgtgta attgagaagc aatgtctgag aaaatggaat tttacagcct ctatagaata
6661 gtaaaggaaa aatgaagtgg gatacgaatc tggaaggctt ctgttgacac aaaatgaagg
6721 tgtacaacaa ggagggcagc tttccacgag gaacttccat gaggctgtgc agccagagag
6781 gaatagggta acaaccctgg tacagctaac acctccaaca cgtgtgtgag cactgtctgc
6841 aagccataac catagcagtg gcaggacagg ctcgccaact gagtggttct ggaaagctgc
6901 cttttccttt tagtgattca aggatgcttc aacgtggatt ttttagttcc tgttatgagc
6961 cagtgaatac aaagatgaac atggtagatg ggggatctgg cttctggagc ttaaaactcc
7021 aggatgggga tctggcttcc tggagcaaga aaaccagtgg ttttcttggc cgaagaagtg
7081 aagagaacaa acagcagagg ataatttggt aatcagcatc ctagtgtgcc ccagggtact
7141 ctcttaagga aatccagtcc tggagcacac ccagtatggt ccagcctgct gtcttcgtag
7201 gtctgagtgc cccagtattt gcaaagtgtt ttggagccta tgaaatgctt tcacacatac
7261 aaatctcctt taattaactc tcacaatgac tctgtgccat gtgtacaatt atcacgtttt
7321 acacacaagg aaactgaggc atggagcatt gtaataatac ccgagatctt ctcactccat
7381 gaccaatgct tttcttctcc attccagttg ctttttcaac tgtgatgatt tataaggaca
7441 atcaaatggg cacataccta tatttatgca catacataca cacacacaca cacacacaca
7501 cacacaacca gatgtcattt ataatccatg taaaatattt ttggggaagt ttctctttaa
7561 taaagtttga agagacatat attttttttt tttgaagagg catatttttt ctaacttttt
7621 tttttttttt tgagatggag tcttgctctg tcacccaggc tggagtgcag ccggtacgat
7681 cacggctcac tgcaacctcc gcctcctggg ttcaagcgat tcttcagctt cagcctcctg
7741 agtagctggg attacagcat gtgccaccat gcctggctaa tttttttttt tttgtatttt
7801 tagtagagat gggggtttca ccatgtttgt gaggctggtc tcgaactcct gacctcaagt
7861 gattcaccta ccttggcctc ccaaagtgct gggattacag tgtgagtcat cacacccagc
7921 ctataacttt tttttaatag gtgatagaat cccgtgcttg aaaaataatc aaacaaaaag
7981 agaatgcatt gtaagaagcc tcactgtact cctgtcccca gctgcccagt tctcccctcc
8041 tcccacaggg aaacatcttc attagtttca ttaggttctt atgaaacctt ccagagtttc
8101 tttaagcaaa atacaagcaa gtaggactgt catatcctgc agaccgctac atacaaatac
8161 atagaaagtg tcctcattct atcctccagt gatattccat tttttggctg aaccacctaa
8221 atgatggata tttaggggaa gcaagtattt tttaaaaaag gtaaaaatca aaggttttta
8281 ttttttattt ttttaaagaa aagttggtag gctgtgttta ttcattcaga agtcaggccg
8341 tggctgaact gatagctctt ggagatggcc attgctcatc tctgaatgtc tggttttctc
8401 ttgtaagaat tgtgtgtatg atccagacct tcagtgtgtg cactatatat tgagaattcc
8461 agaagagatg atatggacaa gaaaaaaaga tgactttact ttttacagta aaaataaaac
8521 ttaaattgaa gagtacaatt gtttaaacaa ttggaactta cttagctact gcttgttgaa
8581 acaaaatcct ttttttaaaa ggtatcgaag caaattaaag ctgatccgtg ctaaggaaga
8641 agacagtggc cattatacta ttgtagctca aaatgaagat gctgtgaaga gctatacttt
8701 tgaactgtta actcaaggta tgtaaaggga gtataaagat aatgctagct ctgtagatga
8761 gtgtcttcca aggaaagcct ggcacttttc tccccggtca tggaagaaaa gcagcactta
8821 ggggagaagc agtgtctgca tatgtcacat atcgggaata cctctgctgg actcatgaat
8881 tcaggtattt ctgggaggtt ctgggttact ctagagtagg cgaggaatcc ctaggctcca
8941 ccagctagct ttatttttgt agagatggag tcttgccatg ttgctcaggc tggtctcctg
9001 ggttcaagct atcttcccac cttggcctct caaagtactg ggattacagg tgtgagccac
9061 tgcacctggc ctccaccagc ttacttagca cctgcttctc aatctgagaa gagagaagca
9121 gatgacctta gattgttctg gagagttttg ctacaagttt tccttataga cattgtacag
9181 tggtccttac cagaagggag tcccaagtct gtttacattc aggctcagca cctatccaga
9241 gtcccagcca tgagccaggt gctgtctgag gtgcgctcat gtgatcctca cagtaaaacc
9301 tgtgatacaa gcaacaccgt atatctaatt tatttgacca cagatttaga aaagaatctt
9361 taaaacctaa taacatacca cagatgcatt ttggtaaatg ctgctttaga ttatacttta
9421 gctgaatcca ttagttgaat cctaagctat aatataattt taagaacctc cttgcctttc
9481 aagccaaata accaagggac tttctctcct ctttccctcc ctcccttcct tccttccttc
9541 cttcttctct ccctcccttg ttatctcttt tccttccctt tctctccttc cttccctctt
9601 ccctttttcc tttctctcct tccttccttc cttgcttcct tcttccctcc ctcctttgtt
9661 ctctcttttc ctttcctttc tctttttctt tccttccttc cttcctcact cactcttttc
9721 ttttcctttc tctccttcct tccttccttc ctccctccct cactctctct tttctttgcc
9781 tttctctcct tccttccttc cttttcctcc ctccctccct cccttgttct cccttttcct
9841 tccttccttc tttccttcct tccttccttc cctcttccct cactctctct tttcctttcc
9901 tctcctttcc ttccttcctt cattctcccc tcccctcccc cctcccctcc ccccccccct
9961 cccccctccc cccctcccct ccccttccct tcccttccca tttttcttct caccatgttg
10021 cccaggcttg ctcaaactcc tgggctcaag tgtttctctt ccacctcagc ctcccaagta
10081 gctggggcta catgtgtgag gcatcacaac catggacttt tcactttctt cactccaggt
10141 taaaaacatc acagggataa atctcaaaac accaaaactg tgaaaatgct gctaaccatg
10201 tgggtctgtc taaactggag tgttacttgt acaactggtt tcagccctcc ggagtgtttt
10261 gaatgccatg tagatgagtt gtgaactcat attccacttt gtagtctcat atgttctggg
10321 acacgagcta ttccattctg acttctttct gcctcttgca gttccttcat ccattctgga
10381 cttggtcgat gatcaccatg gctcaactgg gggacagacg gtgaggtgca cagctgaagg
10441 cacgccgctt cctgatattg agtggatgat atgcaaagat attaagaagt atggaaaaca
10501 gatgtgtctt cttctttcgt ggtcagaata tttctccctt gacacaaatg atgtcaaata
10561 cattttactt attgactata agatagggtt ttgggtgtga tagcttcagg gtgtgtatct
10621 tttgtcatga atagctgtga gaagaaggtc cagggctctc attagacctt caaaatgtct
10681 ccaatctaaa aacaagagtg aattttaaga accactgttc taagaagatt tttactaccc
10741 tggctcacat atcttatttg gtgaactttg tttggtagtc ggactgcatg taaacataaa
10801 tgtgactgct tagtccctta tctgcccacc tgctgtttgg tgggttaatt cgccattccc
10861 tcctccctcc cccgagtcct cagccttctt aaatgggcac atgagcaatg tgtttacact
10921 tcatccatgg taactggttg tgttcagaag cctcagttgt ttcttcctct agacagagac
10981 tcctcatctt aacttctagg gctaagaaca gacttggatg ttgactgggg tttctagtag
11041 attccagtgt ggagcaggat tctaggtctt ataactcaat ctgaggatca tcgcaaccct
11101 agtgacaccc taggggctct tcccagtgtg agtgttgaga agggagggct ccaggccttt
11161 ttgaaggggt gggagattga gatcattaaa tatggttgaa gttgaactgt tcagtttgct
11221 cataggttca agattgggga atggtagtca tattttatta aacttgatta tctctgcctg
11281 ctatgtaaac acttagcttt cagttgttca tgtgtgagtt attccctctt cagcacatgc
11341 agacaagttt taatgttcat ctgcatgtaa aataaatcag tgtgtattgc cccgaaatgc
11401 agacaaggtc ccaactcctt gccatcttag agtgttcccg tggctccact cattgccatg
11461 actctcagga attggcccta tacttaggcc ctttttctct ctagatgtaa taatgaaact
11521 tcctggacta ttttggccaa caatgtctca aacatcatca cggagatcca ctcccgagac
11581 aggagtaccg tggagggccg tgtgactttc gccaaagtgg aggagaccat cgccgtgcga
11641 tgcctggcta agaatctcct tggagctgag aaccgagagc tgaagctggt ggctcccagt
11701 gagttcctca acagtcagga caactcatca gctgagccgc atctgccccn nnnnnnnnnn
11761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
11821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnt cattgtgcct ctctctcttg tcacgtagcc
11881 ctgcgttctg aactcacggt ggctgctgca gtcctggtgc tgttggtgat tgtgatcatc
11941 tcacttattg tcctggttgt catttggaaa caggtagata ttttctcata aaactaaaga
12001 tctttgaagc caatgagaac aagcatagca acctagttca gtgcttggca cagagaagga
12061 gctcagcaat tacatgtgga gtgaacgttg ttggactcta ctgtgtccag tcactgtgct
12121 gcttcagtga agctctggtg cactgggact ttggtaattc accagttacc tgtcctggtc
12181 atttatagaa accgaggtat gaaattcgct ggagggtcat tgaatcaatc agcccggatg
12241 gacatgaata tatttatgtg gacccgatgc agctgcctta tgactcaaga tgggagtttc
12301 caagagatgg actagtgctt ggtaagttcc atggggtaac ctcccaagac tcccttttcc
12361 cttgcacaca actttacaat ttataggcct tggcagaata gagatctgag cttgtgctta
12421 gtaagaacta ggcaatggaa atttgctttc agaaatacat ttctgtctnn nnnnnnnnnn
12481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
12541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnga gtttttgggg tgttaatgat tcttgcctgc
12601 ccacaggtcg ggtcttgggg tctggagcgt ttgggaaggt ggttgaagga acagcctatg
12661 gattaagccg gtcccaacct gtcatgaaag ttgcagtgaa gatgctaaaa cgtaagtgct
12721 ccttcctggg gattttttnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
12781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnntg
12841 ttatttccag tgacgtcttt ttactagaaa gaccaggaag tagttattag cactgaggcc
12901 aagtagctat ctgcttcttt tagacttctg gtaaatagaa tgatatccaa tcacaggatt
12961 agtcatattc ttggtttttt tctgagaaca ggaagatggt agctcagctg gactgatatg
13021 tgatttattc tttcaacagc cacggccaga tccagtgaaa aacaagctct catgtctgaa
13081 ctgaagataa tgactcacct ggggccacat ttgaacattg taaacttgct gggagcctgc
13141 accaagtcag gtgggctcac tgacctggag tgaggatttt cactggacac atgtggttgt
13201 gaaaactgtt caatcaggcn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
13261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnng
13321 ttggggaagg gccgatcggt gcgggcctcc ttcgctatta cgccagctgg cgaaaggggg
13381 atgtgctgca aggcgattaa gttgggtaac gccagggttt tcccagtcac gacgttgtaa
13441 aacgacggcc agtgaattgt aatacgactc actatagggc gaattggagc tccaccgcgg
13501 tggcggccgc tctagaacta gtggatcccc cgggctgcag gacaattcat ggcttttctg
13561 ttcttcattt tcatacccat ctcctaacgg cttttgtccc cataggcccc atttacatca
13621 tcacagagta ttgcttctat ggagatttgg tcaactattt gcataagaat agggatagct
13681 tcctgagcca ccacccagag aagccaaaga aagagctgga tatctttgga ttgaaccctg
13741 ctgatgaaag cacacggagg tgggtgcaaa gagagatgtt gctgtctatc attatcttac
13801 aggcatcaca aatggaaaga cccatgtcct gatagatatc atgtctgcag gaattcgata
13861 tcaagcttat cgataccgnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
13921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnag
13981 tggaatgacc acttcagaag ggcaccctgg gtaagatttc tctttctgtt tttacagcta
14041 tgttatttta tcttttgaaa acaatggtga ctacatggac atgaagcagg ctgatactac
14101 acagtatgtc cccatgctag aaaggaaaga ggtttctaaa tattccgaca tccagagatc
14161 actctatgat cgtccagcct catataagaa gaaatctatg ttaggtaaaa gtgtctatac
14221 tcactctggg tgttgggact ttccagtggt ttaatatgat acttaaagta tttagaggga
14281 agtgtatagg gatggtaagt gaacctggca gnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
14341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
14401 nnnnnnnnnn nacctgatga tttcctgctg cctgccagca ccaatacatt taatttcttt
14461 tctgcagact cagaagtcaa aaacctcctt tcagatgata actcagaagg ccttacttta
14521 ttggatttgt tgagcttcac ctatcaagtt gcccgaggaa tggagttttt ggcttcaaaa
14581 aatgtaagtt caaggcaaca cagacctttt tagacccaga tttcagtgag tggagtgtgg
14641 aaggagatgc taggagatag atgttggaaa ggnnnnnnnn nnnnnnnnnn nnnnnnnnnn
14701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
14761 nnnnnnnnnn nnagtgccac catggatcag ccagtcttgc aggggtgatg ctatatcagc
14821 tacagatggc ttgatcctga gtcatttctt ccttttccat gcagtgtgtc caccgtgatc
14881 tggctgctcg caacgtcctc ctggcacaag gaaaaattgt gaagatctgt gactttggcc
14941 tggccagaga catcatgcat gattcgaact atgtgtcgaa aggcagtgta cgtccacact
15001 tcccacactg gacaggctca tcctcccaca ctttactctc taaannnnnn nnnnnnnnnn
15061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
15121 nnnnnnnnnn nnnnnnnnnn nnnntgaact catgtgcccg tgatacctgt aatcggctca
15181 taagatcatt ggatctgttc ttagttttgt tcccaggaat atctaaaaat aggaaactgg
15241 tccattcagg gcttacacct tttgggtgaa aattcaggat taatgttttt ggatattatt
15301 cctttggagg acataaaagg caatattgac cattcatcat tcatctagta tttattgagc
15361 acctactatg tgccagggac tgagagttca gtaatgaaca aaacacatgt aaaagacact
15421 caaatgggac aagataatta gcacaagtta ttaagagccc aaggggaacc cttttctatt
15481 tccactgctg tggatcatca gtgagtagac atgggtttaa ctgtctccct ccttccttgc
15541 agacctttct gcccgtgaag tggatggctc ctgagagcat ctttgacaac ctctacacca
15601 cactgagtga tgtctggtct tatggcattc tgctctggga gatcttttcc cttggtatgg
15661 gcctgacatn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
15721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnna ggctatagga
15781 tctgtgaggg tttctaacag tgttctatca tgccaagtgt ttcaccgatg cactgagcgt
15841 ttgttagtac ctggtgtttt attgtttggc ttttaggtgg caccccttac cccggcatga
15901 tggtggattc tactttctac aataagatca agagtgggta ccggatggcc aagcctgacc
15961 acgctaccag tgaagtgtga gctccttccc catcccgggg gcctgtgttc acagtctgtg
16021 ggtctagggg gagggagggg ccctgagact tccccctgtg cccactcttg agttctgtcc
16081 ccacagctac gagatcatgg tgaaatgctg gaacagtgag ccggagaaga gaccctcctt
16141 ttaccacctg agtgagattg tggagaatct gctgcctgga caatataaaa aggtgtgttt
16201 ggatctgtgg gtggaaaggt ctggataaag ctggaagtta taccagtgag ctgtnnnnnn
16261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
16321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnttttga ggtttggttg ttaacacttg
16381 attaaatatg ttcaatgaat gtttatagag ttatgaaaaa attcacctgg acttcctgaa
16441 gagtgaccat cctgctgtgg cacgcatgcg tgtggactca gacaatgcat acattggtgt
16501 cacctacaaa aacgaggaag acaagctgaa ggactgggag ggtggtctgg atgagcagag
16561 actgagcgct gacagtggct acatcattcc tctgcctgac attgaccctg tccctgagga
16621 ggaggacctg ggcaagagga acagacacag gtagctgtgg gggcagcctc ggtgtctcac
16681 ctttcccctc ccctataggc cctgannnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
16741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
16801 nnnnntcgtt tgtctctggg gggccacagt cctaggtcta gttctgtgta ggagttgtaa
16861 tattgctctt ctctccctcc tccagctcgc agacctctga agagagtgcc attgagacgg
16921 gttccagcag ttccaccttc atcaagagag aggacgagac cattgaagac atcgacatga
16981 tggacgacat cggcatagac tcttcagacc tggtggaaga cagcttcctg taactggcgg
17041 attcgagggg ttccttccac ttctggggcc acctctggat cccgttc
//