LOCUS D45915 2584 bp mRNA linear HUM 27-DEC-2006
DEFINITION Homo sapiens mRNA for p80 protein, complete cds.
ACCESSION D45915
VERSION D45915.1
KEYWORDS tyrosine kinase fused to nucleophosmin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2584)
AUTHORS Fujimoto,J.
TITLE Direct Submission
JOURNAL Submitted (13-FEB-1995) to the DDBJ/EMBL/GenBank databases.
Contact:Jiro Fujimoto
Institute of Medical Science, University of Tokyo, Depertment of
Oncology; 4-6-1 Shirokane-dai, Minato-ku, Tokyo 108, Japan
REFERENCE 2
AUTHORS Fujimoto,J.
TITLE Human mRNA for p80 protein, complete cds.
JOURNAL Unpublished (1996)
REFERENCE 3
AUTHORS Fujimoto,J., Shiota,M., Iwahara,T., Seki,N., Sato,H., Mori,S. and
Yamamoto,T.
TITLE Characterization of the transforming activity of p80, a
hyperphosphorylated protein in a Ki-1 lymphoma cell line with
chromosomal translocation t(2;5)
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 93, 4181-4186 (1996)
COMMENT
FEATURES Location/Qualifiers
source 1..2584
/cell_line="AMS3"
/cell_type="Ki-1 lymphoma"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
/sex="male"
5'UTR 1..89
CDS 90..2132
/codon_start=1
/function="tyrosine kinase fused to nucleophosmin"
/product="p80 protein"
/protein_id="BAA08343.1"
/translation="MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSL
RTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRL
KCGSGPVHISGQHLVVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAG
KTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSE
QDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPS
QPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMA
RDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPS
KSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDP
DVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTS
SGKAAKKPTAAEVSVRVPRGPAVEGGHVNMAFSQSNPPSELHRVHGSRNKPTSLWNPT
YGSWFTEKPTKKNNPIAKKEPHERGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTA
NMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNSMNQPGP"
3'UTR 2130..2584
regulatory 2560..2565
/regulatory_class="polyA_signal_sequence"
polyA_site 2584
BASE COUNT 652 a 660 c 672 g 600 t
ORIGIN
1 gtgattccgt cctgcgcggt tgttctctgg agcagcgttc ttttatctcc gtccgccttc
61 tctcctacct aagtgcgtgc cgccacccga tggaagattc gatggacatg gacatgagcc
121 ccctgaggcc ccagaactat cttttcggtt gtgaactaaa ggccgacaaa gattatcact
181 ttaaggtgga taatgatgaa aatgagcacc agttatcttt aagaacggtc agtttagggg
241 ctggtgcaaa ggatgagttg cacattgttg aagcagaggc aatgaattac gaaggcagtc
301 caattaaagt aacactggca actttgaaaa tgtctgtaca gccaacggtt tcccttgggg
361 gctttgaaat aacaccacca gtggtcttaa ggttgaagtg tggttcaggg ccagtgcata
421 ttagtggaca gcacttagta gtgtaccgcc ggaagcacca ggagctgcaa gccatgcaga
481 tggagctgca gagccctgag tacaagctga gcaagctccg cacctcgacc atcatgaccg
541 actacaaccc caactactgc tttgctggca agacctcctc catcagtgac ctgaaggagg
601 tgccacggaa aaacatcacc ctcattcggg gtctgggcca tggagccttt ggggaggtgt
661 atgaaggcca ggtgtccgga atgcccaacg acccaagccc cctgcaagtg gctgtgaaga
721 cgctgcctga agtgtgctct gaacaggacg aactggattt cctcatggaa gccctgatca
781 tcagcaaatt caaccaccag aacattgttc gctgcattgg ggtgagcctg caatccctgc
841 cccggttcat cctgctggag ctcatggcgg ggggagacct caagtccttc ctccgagaga
901 cccgccctcg cccgagccag ccctcctccc tggccatgct ggaccttctg cacgtggctc
961 gggacattgc ctgtggctgt cagtatttgg aggaaaacca cttcatccac cgagacattg
1021 ctgccagaaa ctgcctcttg acctgtccag gccctggaag agtggccaag attggagact
1081 tcgggatggc ccgagacatc tacagggcga gctactatag aaagggaggc tgtgccatgc
1141 tgccagttaa gtggatgccc ccagaggcct tcatggaagg aatattcact tctaaaacag
1201 acacatggtc ctttggagtg ctgctatggg aaatcttttc tcttggatat atgccatacc
1261 ccagcaaaag caaccaggaa gttctggagt ttgtcaccag tggaggccgg atggacccac
1321 ccaagaactg ccctgggcct gtataccgga taatgactca gtgctggcaa catcagcctg
1381 aagacaggcc caactttgcc atcattttgg agaggattga atactgcacc caggacccgg
1441 atgtaatcaa caccgctttg ccgatagaat atggtccact tgtggaagag gaagagaaag
1501 tgcctgtgag gcccaaggac cctgaggggg ttcctcctct cctggtctct caacaggcaa
1561 aacgggagga ggagcgcagc ccagctgccc caccacctct gcctaccacc tcctctggca
1621 aggctgcaaa gaaacccaca gctgcagagg tctctgttcg agtccctaga gggccggccg
1681 tggaaggggg acacgtgaat atggcattct ctcagtccaa ccctccttcg gagttgcaca
1741 gggtccacgg atccagaaat aagcccacca gcttgtggaa cccaacgtac ggctcctggt
1801 ttacagagaa acccaccaaa aagaataatc ctatagcaaa gaaggagcca cacgagaggg
1861 gtaacctggg gctggaggga agctgtactg tcccacctaa cgttgcaact gggagacttc
1921 cgggggcctc actgctccta gagccctctt cgctgactgc caatatgaag gaggtacctc
1981 tgttcaggct acgtcacttc ccttgtggga atgtcaatta cggctaccag caacagggct
2041 tgcccttaga agccgctact gcccctggag ctggtcatta cgaggatacc attctgaaaa
2101 gcaagaatag catgaaccag cctgggccct gagctcggtc gcacactcac ttctcttcct
2161 tgggatccct aagaccgtgg aggagagaga ggcaatcaat ggctcctttc acaaaccaga
2221 gaccaaatgt cacgttttgt tttgtgccaa cctattttga agtaccacca aaaaagctgt
2281 attttgaaaa tgctttagaa aggttttgag catgggttca tcctattctt tcgaaagaag
2341 aaaatatcat aaaaatgagt gataaataca aggccagatg tggttgcata aggtttttat
2401 gcatgtttgt tgtatacttc cttatgcttc ttttaaattg tgtgtgctct gcttcaatgt
2461 agtcagaatt agctgcttct atgtttcata gttggggtca tagatgtttc cttgccttgt
2521 tgatgtggac atgagccatt tgaggggaga gggaacggaa ataaaggagt tatttgtaat
2581 gact
//