LOCUS HUMMTG8AP 3460 bp mRNA linear HUM 26-SEP-2008
DEFINITION Homo sapiens mRNA for MTG8a protein, complete cds.
ACCESSION D43638 D14820
VERSION D43638.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3460)
AUTHORS Miyoshi,H.
TITLE Direct Submission
JOURNAL Submitted (21-NOV-1994) to the DDBJ/EMBL/GenBank databases.
Contact:Hiroyuki Miyoshi
National Cancer Center Research Institute, Radiobiology Division;
5-1-1 Tukiji, Chuo-ku, Tokyo 104, Japan
REFERENCE 2 (bases 1 to 2580)
AUTHORS Miyoshi,H., Kozu,T., Shimizu,K., Enomoto,K., Maseki,N., Kaneko,Y.,
Kamada,N. and Ohki,M.
TITLE The t(8;21) translocation in acute myeloid leukemia results in
production of an AML1-MTG8 fusion transcript
JOURNAL EMBO J. 12, 2715-2721 (1993)
REFERENCE 3 (bases 2581 to 3460)
AUTHORS Niwa-Kawakita,M., Miyoshi,H., Gotoh,O., Matsushima,Y.,
Nishimura,M., Shisa,H. and Ohki,M.
TITLE Cloning and gene mapping of the mouse homologue of the CBFA2T1
gene associated with human acute myeloid leukemia
JOURNAL Genomics 29, 755-759 (1995)
COMMENT
FEATURES Location/Qualifiers
source 1..3460
/chromosome="8"
/db_xref="H-InvDB:HIT000101469"
/db_xref="taxon:9606"
/dev_stage="fetus"
/map="8q22"
/mol_type="mRNA"
/note="acute myeloid leukemia"
/organism="Homo sapiens"
/sex="female"
/tissue_type="brain"
5'UTR 1..411
CDS 412..2145
/codon_start=1
/product="MTG8a protein"
/protein_id="BAA07755.1"
/translation="MPDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSF
TPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRF
LTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKA
NLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTP
DRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLD
DMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLL
NCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGGSSSSHSRQQSPV
NPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHD
MITTERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYC
GSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTP
GTPSTIETTPR"
3'UTR 2146..3460
polyA_site 3460
BASE COUNT 1017 a 881 c 761 g 801 t
ORIGIN
1 tgaataaatt attcggcatt tagcttatca ttctgaattt cactttttgc tttttggtgc
61 tctgaaactt gcagagagag gtggagtgct aaggggaggg taggggttgt gatactttgc
121 acacacatcc ctgtcattgt tctgcctaaa gagacagggc tgggttcaag gccacatgtg
181 ctcctgtcat cctccacatt tctgctccaa gtgcaatccg gagtgtcagc tctccatctg
241 tctctgcctg gcaggcgcac gcgcccagca ccctgcctcc ggcgatgccg ccccagcccc
301 tctgatggcc ctcctctctg ctgccactca ttccagaaca ggaggcatga gcccggaacg
361 cgcttgcttt taggagacag ccactttctg tgtggtacgc tggattcaag gatgcctgat
421 cgtactgaga agcactccac aatgccagac tcacctgtgg atgtgaagac gcaatctagg
481 ctgactcctc caacaatgcc acctccccca actactcaag gagctccaag aaccagttca
541 tttacaccga caacgttaac taatggcacg agccattctc ctacagcctt gaatggcgcc
601 ccctcaccac ccaatggctt cagcaatggg ccttcctctt cttcctcctc ctctctggct
661 aatcaacagc tgcccccagc ctgtggtgcc aggcaactca gcaagctgaa aaggttcctt
721 actaccctgc agcagtttgg caatgacatt tcacccgaga taggagaaag agttcgcacc
781 ctcgttctgg gactagtgaa ctccactttg acaattgaag aatttcattc caaactgcaa
841 gaagctacta acttcccact gagacctttt gtcatcccat ttttgaaggc caacttgccc
901 ctgctgcagc gtgagctcct ccactgcgca agactggcca aacagaaccc tgcccagtac
961 ctcgcccagc atgaacagct gcttctggat gccagcacca cctcacctgt tgactcctca
1021 gagctgcttc tcgatgtgaa cgaaaacggg aagaggcgaa ctccagacag aaccaaagaa
1081 aatggctttg acagagagcc tttgcactca gaacatccaa gcaagcgacc atgcactatt
1141 agcccaggcc agcggtacag tccaaataac ggcttatcct accagcccaa tggcctgcct
1201 caccctaccc cacctccacc tcagcattac cgtttggatg atatggccat tgcccaccac
1261 tacagggact cctatcgaca ccccagccac agggacctca gggacagaaa cagacctatg
1321 gggttgcatg gcacacgtca agaagaaatg attgatcaca gactaacaga cagagaatgg
1381 gcagaagagt ggaaacatct tgaccatctg ttaaactgca taatggacat ggtagaaaaa
1441 acaaggcgat ctctcaccgt actaaggcgg tgtcaagaag cagaccggga agaattgaat
1501 tactggatcc ggcggtacag tgacgccgag gacttaaaaa aaggtggcgg cagtagcagc
1561 agccactcta ggcagcagag tcccgtcaac ccagacccag ttgcactaga cgcgcatcgg
1621 gaattccttc acaggcctgc gtctggatac gtgccagagg agatctggaa gaaagctgag
1681 gaggccgtca atgaggtgaa gcgccaggcg atgacggagc tgcagaaggc cgtgtctgag
1741 gcggagcgga aagcccacga catgatcaca acagagaggg ccaagatgga gcgcacggtc
1801 gccgaggcca aacggcaggc ggcggaggac gcactggcag ttatcaatca gcaggaggat
1861 tcaagcgaga gttgctggaa ttgtggccgt aaagcgagtg aaacctgcag tggctgtaac
1921 acagcccgat actgtggctc attttgccag cacaaagact gggagaagca ccatcacatc
1981 tgtggacaga ccctgcaggc ccagcagcag ggagacacac ctgcagtcag ctcctctgtc
2041 acgcccaaca gcggggctgg gagcccgatg gacacaccac cagcagccac tccgaggtca
2101 accaccccgg gaaccccttc caccatagag acaacccctc gctagacgtg aactcagaac
2161 tgtcggagga aagacaacac aaccaacgcg aaaccaattc ctcatcctca gatgctcaaa
2221 gttgtttttt ttgtttgttt gtttattaga tgaattatcc tatttcagta cttcagcaag
2281 agagaaccta actgtatctt gaggtggtag taaaacacag agggccagta acgggtcgta
2341 atgacttatt gtggataaca aagatatctt ttctttagag aactgaaaag agagcagaga
2401 atataacatg aaatgataga tttgacctcc tccctgttat tttcaagtag ctgggatttt
2461 aaactagatg acctcattaa ccgatgcttt accaaacagc aaaccaagag attgctaatt
2521 gctgttgaaa gcaaaaatgc taatattaaa agtcacaatg ttctttatat acaataatgg
2581 aaaaaaaaaa aagaggaaaa ccctcaaggg catgagcatt ggatacagca gtagacattt
2641 taacaagaag atgaatggcg tccgtgggtt gctaactgaa ctttgaagac ccgctacaaa
2701 acgcgcagat gtgcagcaga ttggaaggag acacagatgt tcggtttttt tcctgtttct
2761 gaaaagaaat aataatatcc aggtcaacag aatgaaaaat gaaagatgat ttgcaatggg
2821 atgtatgaat acagcagcaa gaaaaaaaaa tgccataata caaaaggctc catatatata
2881 tatatatata tatatataca cacacacaca cacgcacata tatacacaca cacacacaca
2941 cacacacaca cacacacaca cacacacaca gaagtaagag actcagcctg cagttaatta
3001 gcattctggc agttttgaca tcagccagct gccctaaata acccttcaac gtttcttcac
3061 ttttgcaagt tccacagagt aagacattgg gtctattcca gctcattcat tttatattga
3121 aaaaaataat tttaaaaatg gtggcttcag ctccagcccc tttccaaaat ttttcaaccc
3181 caccctgttt ggatttttaa ttaaaaacta gtagttctct tggtgttaaa acacttctgt
3241 cctgtgaggt ttcccaatgg tgtttttctt gtaaatgtgt tggacaaatg tgaagatgca
3301 ttgtagttta accatatgcc cacatttagt ctctttattc ctagttggtg agaaacctgt
3361 atctttctat gctgctttta tatctgtatg tattagtgat atttctctag tagttaaaaa
3421 aaaaaaaagg aaaaaaagac tctttttggt tgtcctcaag
//