LOCUS D42138 1924 bp mRNA linear HUM 27-SEP-2006
DEFINITION Homo sapiens mRNA for PIG-B, complete cds.
ACCESSION D42138
VERSION D42138.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1924)
AUTHORS Takahashi,M.
TITLE Direct Submission
JOURNAL Submitted (17-NOV-1994) to the DDBJ/EMBL/GenBank databases.
Contact:Minoru Takahashi
Osaka University, Research Institute for Microbial Diseases,
Department of Immunoregulation; 3-1 Yamadaoka, Suita, Osaka 565,
Japan
REFERENCE 2
AUTHORS Takahashi,M., Inoue,N., Ohishi,K., Maeda,Y., Nakamura,N., Endo,Y.,
Fujita,T., Takeda,J. and Kinoshita,T.
TITLE PIG-B, a membrane protein of the endoplasmic reticulum with a
large lumenal domain, is involved in transferring the third
mannose of the GPI anchor
JOURNAL EMBO J. 15, 4254-4261 (1996)
COMMENT
FEATURES Location/Qualifiers
source 1..1924
/cell_line="P39"
/clone_lib="human P39 library in pCEV4"
/db_xref="H-InvDB:HIT000101468"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 45..1709
/codon_start=1
/note="involvement of GPI-anchor biosynthesis"
/note="phosphatidylinositol glycan of complementation
class B"
/product="PIG-B"
/protein_id="BAA07709.1"
/translation="MRRPLSKCGMEPGGGDASLTLHGLQNRSHGKIKLRKRKSTLYFN
TQEKSARRRGDLLGENIYLLLFTIALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYG
YLTWEWTERLRSYTYPLIFASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYS
LMKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNS
VKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMID
RIFFGQWTLVQFNFLKFNVLQNWGTFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLA
PKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSLTHLKTWKKPALSFL
FLSNLFLALYTGLVHQRGTLDVMSHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHC
PLPMRFLQCPPDLTGKSHYLDEADVFYLNPLNWLHREFHDDASLPTHLITFSILEEEI
SAFLISSNYKRTAVFFHTHLPEGRIGSHIYVYERKLKGKFNMKMKF"
regulatory 1902..1907
/regulatory_class="polyA_signal_sequence"
polyA_site 1924
BASE COUNT 532 a 397 c 376 g 619 t
ORIGIN
1 ggctactgca gctttcttcc gccttaggaa ggtggcggcc agggatgagg aggcccctaa
61 gcaagtgcgg aatggagccg gggggcggag atgccagcct cactttgcat ggtctccaga
121 accgctccca cggcaagata aagctgcgaa agagaaagtc taccttgtac ttcaacaccc
181 aggagaagag cgccaggcgc cgcggggatc ttcttggaga aaatatttat ctgctcttgt
241 ttaccatagc tttacgaata ttaaactgct ttttagtgca gacaagtttt gttccagatg
301 aatactggca gtctcttgaa gtttcacatc acatggtttt caattatggt tatttgactt
361 gggaatggac agagagactg aggagttaca cttatccctt aatctttgca agcatttaca
421 agattcttca tcttttaggg aaagatagtg ttcagttgct gatttggatt cctagacttg
481 cccaagcact tctgtctgct gtagcagatg tgagacttta ctcattaatg aagcaactag
541 aaaatcagga agtggcaaga tgggtgtttt tttgccagtt gtgctcctgg ttcacatggt
601 attgctgtac cagaaccctt acaaacacca tggaaactgt tctcactata attgctcttt
661 tctactatcc tttggaaggt tcaaagtcta tgaacagtgt caaatactca tccctggtgg
721 cacttgcctt cataattcgt cccacagctg tcattctgtg gacacctttg ctcttcagac
781 atttctgtca agaaccaaga aagcttgatc ttattctaca tcatttttta cctgtaggct
841 ttgttacttt gagtttgtct ctgatgattg atcgtatttt ttttggccaa tggactctgg
901 ttcaatttaa ttttttgaaa tttaacgtgc tgcagaactg gggaacattt tatggttctc
961 atccatggca ctggtacttc agtcaaggat ttccagttat cttgggtact cacttaccct
1021 tctttattca tggctgctat ctagcaccaa agagataccg gatacttttg gtgactgtgc
1081 tgtggacact gcttgtttat agcatgttga gccacaaaga attcaggttt atttatccag
1141 ttttaccatt ctgtatggtg ttctgtggat actcattaac ccacctgaaa acatggaaga
1201 aaccagctct aagtttcctg tttttatcaa atttgttcct cgccctttat actggtttag
1261 ttcatcaacg aggtactctt gatgtcatga gtcatattca aaaagtttgt tacaacaatc
1321 ccaataaatc ttcagcttca atatttataa tgatgccttg ccactctact ccttattaca
1381 gccatgttca ctgcccactt cccatgagat ttctccagtg cccgccagac ctgactggaa
1441 aaagtcatta tcttgatgaa gcagatgtat tttacctaaa tcccttaaac tggttacata
1501 gagagtttca tgatgatgca tcattgccta ctcacttgat caccttcagc attttggaag
1561 aggaaataag cgctttccta atttcaagca attataaaag aactgctgtt ttcttccaca
1621 ctcacttgcc agagggtcga attggaagtc acatatatgt ctatgaacgg aagttaaaag
1681 ggaaattcaa catgaagatg aaattctgaa ctttcctaga taaattaaca ttgctgggtg
1741 gaaatattca gatgctgctt aaatacttcg gtaaacactg ggtaagattc atggaactta
1801 gaaaaaagct gtatgaactg ctttaccaaa tatcactact gaggaaatgt ataaaatacc
1861 acatagtata aaattacatg ttaatacaat gccagatttt aaataaagac ctttagtttt
1921 cctc
//