LOCUS HUMPK120 3058 bp mRNA linear HUM 07-FEB-2003
DEFINITION Homo sapiens mRNA for PK-120, complete cds.
ACCESSION D38535
VERSION D38535.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3058)
AUTHORS Nishimura,H.
TITLE Direct Submission
JOURNAL Submitted (14-OCT-1994) to the DDBJ/EMBL/GenBank databases.
Contact:Hitoshi Nishimura
Faculty of Pharmaceutical Sciences, Hokkaido University; N12, W6,
Kita-ku, Sapporo, Hokkaido 060, Japan
REFERENCE 2
AUTHORS Nishimura,H., Kakizaki,I., Muta,T., Sasaki,N., Pu,P.X.,
Yamashita,T. and Nagasawa,S.
TITLE cDNA and deduced amino acid sequence of human PK-120, a plasma
kallikrein-sensitive glycoprotein
JOURNAL FEBS Lett. 357, 207-211 (1995)
COMMENT
FEATURES Location/Qualifiers
source 1..3058
/cell_type="hepatocyte"
/clone_lib="lambda gt10"
/db_xref="H-InvDB:HIT000101455"
/db_xref="taxon:9606"
/dev_stage="adult"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="liver"
CDS 130..2922
/codon_start=1
/product="PK-120 precursor"
/protein_id="BAA07536.1"
/translation="MKPPRPVRTCSKVLVLLSLLAIHQTTTAEKNGIDIYSLTVDSRV
SSRFAHTVVTSRVVNRANTVQEATFQMELPKKAFITNFSMIIDGMTYPGIIKEKAEAQ
AQYSAAVAKGKSAGLVKATGRNMEQFQVSVSVAPNAKITFELVYEELLKRRLGVYELL
LKVRPQQLVKHLQMDIHIFEPQGISFLETESTFMTNQLVDALTTWQNKTKAHIRFKPT
LSQQQKSPEQQETVLDGNLIIRYDVDRAISGGSIQIENGYFVHYFAPEGLTTMPKNVV
FVIDKSGSMSGRKIQQTREALIKILDDLSPRDQFNLIVFSTEATQWRPSLVPASAENV
NKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTDGDPTVGE
TNPRSIQNNVREAVSGRYSLFCLGFGFDVSYAFLEKLALDNGGLARRIHEDSDSALQL
QDFYQEVANPLLTAVTFEYPSNAVEEVTQNNFRLLFKGSEMVVAGKLQDRGPDVLTAT
VSGKLPTQNITFQTESSVAEQEAEFQSPKYIFHNFMERLWAYLTIQQLLEQTVSASDA
DQQALRNQALNLSLAYSFVTPLTSMVVTKPDDQEQSQVAEKPMEGESRNRNVHSGSTF
FKYYLQGAKIPKPEASFSPRRGWNRQAGAAGSRMNFRPGVLSSRQLGLPGPPDVPDHA
AYHPFRRLAILPASAPPATSNPDPAVSRVMNMKIEETTMTTQTPAPIQAPSAILPLPG
QSVERLCVDPRHRQGPVNLLSDPEQGVEVTGQYEREKAGFSWIEVTFKNPLVWVHASP
EHVVVTRNRRSSAYKWKETLFSVMPGLKMTMDKTGLLLLSDPDKVTIGLLFWDGRGEG
LRLLLRDTDRFSSHVGGTLGQFYQEVLWGSPAASDDGRRTLRVQGNDHSATRERRLDY
QEGPPGVEISCWSVEL"
sig_peptide 130..213
mat_peptide 214..2919
/experiment="experimental evidence, no additional details
recorded"
/product="PK-120"
regulatory 3033..3038
/regulatory_class="polyA_signal_sequence"
BASE COUNT 722 a 910 c 842 g 584 t
ORIGIN
1 gccccacagt gagaggaagg aaggcaacag tcgccagcag ccgatgtgaa gaccggactc
61 cgtgcgcccc tcgccgcctc tgcctggcca catcgatgtt gtgtccgccg cctgctcgcc
121 cggatcacga tgaagccccc aaggcctgtc cgtacctgca gcaaagttct cgtcctgctt
181 tcactgctgg ccatccacca gactactact gccgaaaaga atggcatcga catctacagc
241 ctcaccgtgg actccagggt ctcatcccga tttgcccaca cggtcgtcac cagccgagtg
301 gtcaataggg ccaatactgt gcaggaggcc accttccaga tggagctgcc caagaaagcc
361 ttcatcacca acttctccat gatcatcgat ggcatgacct acccagggat catcaaggag
421 aaggctgaag cccaggcaca gtacagcgca gcagtggcca agggaaagag cgctggcctc
481 gtcaaggcca ccgggagaaa catggagcag ttccaggtgt cggtcagtgt ggctcccaat
541 gccaagatca cctttgagct ggtctatgag gagctgctca agcggcgttt gggggtgtac
601 gagctgctgc tgaaagtgcg gccccagcag ctggtcaagc acctgcagat ggacattcac
661 atcttcgagc cccagggcat cagctttctg gagacagaga gcaccttcat gaccaaccag
721 ctggtagacg ccctcaccac ctggcagaat aagaccaagg ctcacatccg gttcaagcca
781 acactttccc agcagcaaaa gtccccagag cagcaagaaa cagtcctgga cggcaacctc
841 attatccgct atgatgtgga ccgggccatc tccgggggct ccattcagat cgagaacggc
901 tactttgtac actactttgc ccccgagggc ctaaccacaa tgcccaagaa tgtggtcttt
961 gtcattgaca agagcggctc catgagtggc aggaaaatcc agcagacccg ggaagcccta
1021 atcaagatcc tggatgacct cagccccaga gaccagttca acctcatcgt cttcagtaca
1081 gaagcaactc agtggaggcc atcactggtg ccagcctcag ccgagaacgt gaacaaggcc
1141 aggagctttg ctgcgggcat ccaggccctg ggagggacca acatcaatga tgcaatgctg
1201 atggctgtgc agttgctgga cagcagcaac caggaggagc ggctgcccga agggagtgtc
1261 tcactcatca tcctgctcac cgatggcgac cccactgtgg gggagactaa ccccaggagc
1321 atccagaata acgtgcggga agctgtaagt ggccggtaca gcctcttctg cctgggcttc
1381 ggtttcgacg tcagctatgc cttcctggag aagctggcac tggacaatgg cggcctggcc
1441 cggcgcatcc atgaggactc agactctgcc ctgcagctcc aggacttcta ccaggaagtg
1501 gccaacccac tgctgacagc agtgaccttc gagtacccaa gcaatgccgt ggaggaggtc
1561 actcagaaca acttccggct cctcttcaag ggctcagaga tggtggtggc tgggaagctc
1621 caggaccggg ggcctgatgt gctcacagcc acagtcagtg ggaagctgcc tacacagaac
1681 atcactttcc aaacggagtc cagtgtggca gagcaggagg cggagttcca gagccccaag
1741 tatatcttcc acaacttcat ggagaggctc tgggcatacc tgactatcca gcagctgctg
1801 gagcaaactg tctccgcatc cgatgctgat cagcaggccc tccggaacca agcgctgaat
1861 ttatcacttg cctacagctt tgtcacgcct ctcacatcta tggtagtcac caaacccgat
1921 gaccaagagc agtctcaagt tgctgagaag cccatggaag gcgaaagtag aaacaggaat
1981 gtccactcag gttccacttt cttcaaatat tatctccagg gagcaaaaat accaaaacca
2041 gaggcttcct tttctccaag aagaggatgg aatagacaag ctggagctgc tggctcccgg
2101 atgaatttca gacctggggt tctcagctcc aggcaacttg gactcccagg acctcctgat
2161 gttcctgacc atgctgctta ccaccccttc cgccgtctgg ccatcttgcc tgcttcagca
2221 ccaccagcca cctcaaatcc tgatccagct gtgtctcgtg tcatgaatat gaaaatcgaa
2281 gaaacaacca tgacaaccca aaccccagcc cccatacagg ctccctctgc catcctgcca
2341 ctgcctgggc agagtgtgga gcggctctgt gtggacccca gacaccgcca ggggccagtg
2401 aacctgctct cagaccctga gcaaggggtt gaggtgactg gccagtatga gagggagaag
2461 gctgggttct catggatcga agtgaccttc aagaaccccc tggtatgggt tcacgcatcc
2521 cctgaacacg tggtggtgac tcggaaccga agaagctctg cgtacaagtg gaaggagacg
2581 ctattctcag tgatgcccgg cctgaagatg accatggaca agacgggtct cctgctgctc
2641 agtgacccag acaaagtgac catcggcctg ttgttctggg atggccgtgg ggaggggctc
2701 cggctccttc tgcgtgacac tgaccgcttc tccagccacg ttggagggac ccttggccag
2761 ttttaccagg aggtgctctg gggatctcca gcagcatcag atgacggcag acgcacgctg
2821 agggttcagg gcaatgacca ctctgccacc agagagcgca ggctggatta ccaggagggg
2881 cccccgggag tggagatttc ctgctggtct gtggagctgt agttctgatg gaaggagctg
2941 tgcccaccct gtacacttgg cttccccctg caactgcagg gccgcttctg gggcctggac
3001 caccatgggg aggaagagtc ccactcatta caaataaaga aaggtggtgt gagcctga
//