LOCUS HUMHRLFB 3071 bp mRNA linear HUM 15-JUN-2010
DEFINITION Homo sapiens mRNA for hRlf beta subunit (p102 protein), complete
cds.
ACCESSION D38073
VERSION D38073.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3071)
AUTHORS Takisawa,H.
TITLE Direct Submission
JOURNAL Submitted (26-AUG-1994) to the DDBJ/EMBL/GenBank databases.
Contact:Haruhiko Takisawa
Osaka University, Dept. of Biology, Facul. of Science;
Machikaneyama 1-1, Toyonaka, Osaka 560, Japan
REFERENCE 2 (bases 41 to 2606)
AUTHORS Hu,B., Burkhart,R., Schulte,D., Musahl,C. and Knippers,R.
TITLE The P1 family: a new class of nuclear mammalian proteins related
to the yeast Mcm replication proteins
JOURNAL Nucleic Acids Res. 21, 5289-5293 (1993)
REFERENCE 3
AUTHORS Kubota,Y., Mimura,S., Nishimoto,S., Takisawa,H. and Nojima,H.
TITLE Identification of the yeast MCM3-related protein as a component of
Xenopus DNA replication licensing factor
JOURNAL Cell 81, 601-609 (1995)
COMMENT
FEATURES Location/Qualifiers
source 1..3071
/cell_line="HeLa"
/cell_type="epithelian"
/clone_lib="lambda Zap II"
/db_xref="H-InvDB:HIT000101416"
/db_xref="taxon:9606"
/dev_stage="carcinoma"
/haplotype="aneuploid"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="cervix"
misc_difference 41
/citation=[2]
/note="conflict"
/replace="g"
misc_difference 43
/citation=[2]
/note="conflict"
/replace="a"
CDS 78..2504
/codon_start=1
/note="Budding yeast MCM3 homolog"
/note="human P1 protein"
/product="hRlf beta subunit (p102 protein)"
/protein_id="BAA07267.1"
/translation="MAGTVVLDDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDNQ
YRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGL
EGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYS
DLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVD
VILDDDLVDKANAGDRVQVVGTYRCLPGKKGGYTSGTFRTVLIACNVKQMSKDAQPSF
SAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSH
IRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERR
LEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLA
AANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYR
APGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAA
FMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRL
ATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQ
EDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELS
ESRLKAFKVALLDVFREAHAQSIGMNRLTESINRDSEEPFSSVEIQAALSKMQDDNQV
MVSEGIIFLI"
misc_difference 294
/citation=[2]
/note="conflict"
/replace="a"
misc_difference 465
/citation=[2]
/note="conflict"
/replace="t"
misc_difference 467..469
/citation=[2]
/note="conflict"
/replace="atg"
misc_difference 491..492
/citation=[2]
/note="conflict"
/replace="gt"
misc_difference 503
/citation=[2]
/note="conflict"
/replace="t"
misc_difference 578
/citation=[2]
/note="conflict"
/replace="t"
misc_difference 581
/citation=[2]
/note="conflict"
/replace="c"
misc_difference 584
/citation=[2]
/note="conflict"
/replace="a"
misc_difference 627
/citation=[2]
/note="conflict"
/replace="t"
misc_difference 629
/citation=[2]
/note="conflict"
/replace="g"
misc_difference 658
/citation=[2]
/note="conflict"
/replace="g"
misc_difference 660
/citation=[2]
/note="conflict"
/replace="t"
misc_difference 662
/citation=[2]
/note="conflict"
/replace="c"
misc_difference 692
/citation=[2]
/note="conflict"
/replace="a"
misc_difference 719
/citation=[2]
/note="conflict"
/replace="t"
misc_difference 767..768
/citation=[2]
/note="conflict"
/replace="gc"
misc_difference 807
/citation=[2]
/note="conflict"
/replace="g"
misc_difference 968
/citation=[2]
/note="conflict"
/replace="g"
misc_difference 1436
/citation=[2]
/note="conflict"
/replace="t"
misc_difference 1589
/citation=[2]
/note="conflict"
/replace="a"
misc_difference 1593
/citation=[2]
/note="conflict"
/replace="g"
misc_difference 1634
/citation=[2]
/note="conflict"
/replace="a"
misc_difference 2575
/citation=[2]
/note="conflict"
/replace="c"
regulatory 3050..3055
/regulatory_class="polyA_signal_sequence"
polyA_site 3071
BASE COUNT 787 a 743 c 842 g 699 t
ORIGIN
1 gaagttttcg cgccgcggtg gagtcatcct gggaacctcc acgcgacttt ggtggaggta
61 gttctttggc agcgggcatg gcgggtaccg tggtgctgga cgatgtggag ctgcgggagg
121 ctcagagaga ttacctggac ttcctggacg acgaggaaga ccagggaatt tatcagagca
181 aagttcggga gctgatcagt gacaaccaat accggctgat tgtcaatgtg aatgacctgc
241 gcaggaaaaa cgagaagagg gctaaccggc ttctgaacaa tgcctttgag gagctggttg
301 ccttccagcg ggccttaaag gattttgtgg cctccattga tgctacctat gccaagcagt
361 atgaggagtt ctacgtagga ctggaaggca gctttggctc caagcacgtc tccccgcgga
421 ctcttacctc ctgcttcctc agctgtgtgg tctgtgtgga gggcattgtc actaaatgtt
481 ctctagttcg tcccaaagtc gtccgcagtg tccactactg tcctgctact aagaagacca
541 tagagcgacg ttattctgat ctcaccaccc tggtggcctt tccctccagc tctgtctatc
601 ctaccaagga tgaggagaac aatccccttg agacagaata tggcctttct gtctacaagg
661 atcaccagac catcaccatc caggagatgc cggagaaggc cccagccggc cagctccccc
721 gctctgtgga cgtcattctg gatgatgact tggtggataa agcgaacgct ggtgaccggg
781 ttcaggtggt gggaacctac cgttgccttc ctggaaagaa gggaggctac acctctggga
841 ccttcaggac tgtcctgatt gcctgtaatg ttaagcagat gagcaaggat gctcagccct
901 ctttctctgc tgaggatata gccaagatca agaagttcag taaaacccga tccaaggata
961 tctttgacca gctggccaag tcattggccc caagtatcca tgggcatgac tatgtcaaga
1021 aagcaatcct ctgcttgctc ttgggagggg tggaacgaga cctagaaaat ggcagccaca
1081 tccgtgggga catcaatatt cttctaatag gagacccatc cgttgccaag tctcagcttc
1141 tgcggtatgt gctttgcact gcaccccgag ctatccccac cactggccgg ggctcctctg
1201 gagtgggtct gacggctgct gtcaccacag accaggaaac aggagagcgc cgtctggaag
1261 caggggccat ggtcctggct gaccgaggcg tggtttgcat tgatgaattt gacaaaatgt
1321 ctgacatgga tcgcacagcc atccatgaag tgatggagca gggtcgagtg accattgcca
1381 aggctggcat ccatgctcgg ctgaatgccc gctgcagtgt tttggcagct gccaaccctg
1441 tctacggcag gtatgaccag tataagactc caatggagaa cattgggcta caggactcac
1501 tgctgtcacg atttgacttg ctcttcatca tgctggatca gatggatcct gagcaggatc
1561 gggagatctc agaccatgtc cttcggatgc accgttacag agcacctggg gagcaggatg
1621 gcgatgctat gcccttgggt agtgctgtgg atatcctggc cacagatgat cccaacttta
1681 gccaggaaga tcagcaggac acccagattt atgagaagca tgacaacctt ctacatggga
1741 ccaagaagaa aaaggagaag atggtgagtg cagcattcat gaagaagtac atccatgtgg
1801 ccaaaatcat caagcctgtc ctgacacagg agtcggccac ctacattgca gaagagtatt
1861 cacgcctgcg cagccaggat agcatgagct cagacaccgc caggacatct ccagttacag
1921 cccgaacact ggaaactctg attcgactgg ccacagccca tgcgaaggcc cgcatgagca
1981 agactgtgga cctgcaggat gcagaggaag ctgtggagtt ggtccagtat gcttacttta
2041 agaaggttct ggagaaggag aagaaacgta agaagcgaag tgaggatgaa tcagagacag
2101 aagatgaaga ggagaaaagc caagaggacc aggagcagaa gaggaagaga aggaagactc
2161 gccagccaga tgccaaagat ggggattcat acgaccccta tgacttcagt gacacagagg
2221 aggaaatgcc tcaagtacac actccaaaga cggcagactc acaggagacc aaggaatccc
2281 agaaagtgga gttgagtgaa tccaggttga aggcattcaa ggtggccctc ttggatgtgt
2341 tccgggaagc tcatgcgcag tcaatcggca tgaatcgcct cacagaatcc atcaaccggg
2401 acagcgaaga gcccttctct tcagttgaga tccaggctgc tctgagcaag atgcaggatg
2461 acaatcaggt catggtgtct gagggcatca tcttcctcat ctgaggaggc ctcgtctctg
2521 aacttgggtt gtgccgagag agtttgttct gtgtttccca ccctctccct gaccaaagtc
2581 tttgcctcta ctcccttaac agtgttgaat tcaactgaag ccgaggaatg ttggtgatga
2641 agctgagttc aggactcggt ggaccctttg ggaatgggtc atgaaagctg ccatggggtg
2701 aggaaagagg agacagtggg agaggacaat gactattgca tcttcattgc aaaagcactg
2761 gctcatccgc cctacttccc atcccacaca aacccaattg taaataacat atgacttctg
2821 agtacttttg ggggcacaac tgttttctgt ttgctgtttt tttgttttgt tttttttctc
2881 cagagcactt tggtctagac taggctttgg gtggttccaa ttggtggaga gaagctctga
2941 ggcacgtcat gcaggtcaag aaagctttct ttgcagtagc accagttaag gtgaatatgt
3001 attgtatcac aaaacaaacc caatatccag atgaatatcc gagatgttga ataaacttag
3061 ccatttcgta c
//