LOCUS HUMLIMKA 3262 bp mRNA linear HUM 08-FEB-2003
DEFINITION Homo sapiens LIMK mRNA for LIM kinase, complete cds.
ACCESSION D26309
VERSION D26309.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3262)
AUTHORS Mizuno,K.
TITLE Direct Submission
JOURNAL Submitted (24-DEC-1993) to the DDBJ/EMBL/GenBank databases.
Contact:Kensaku Mizuno
Faculty of Science, Kyushu University, Department of Biology;
6-10-1 Hakozaki, Higashi-ku, Fukuoka, Fukuoka 812, Japan
REFERENCE 2
AUTHORS Mizuno,K., Okano,I., Ohashi,K., Nunoue,K., Kuma,K., Miyata,T. and
Nakamura,T.
TITLE Identification of a human cDNA encoding a novel protein kinase
with two repeats of the LIM/double zinc finger motif
JOURNAL Oncogene 9, 1605-1612 (1994)
COMMENT
FEATURES Location/Qualifiers
source 1..3262
/cell_line="HepG2"
/clone_lib="lambda ZAPII"
/db_xref="H-InvDB:HIT000101149"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 96..2039
/codon_start=1
/gene="LIMK"
/note="initiation codon I: 96-98 bp, initiation codon II:
138-140 bp."
/note="non-receptor type protein kinase"
/note="zinc finger domain (LIM motif) I: 168-320 bp, zinc
finger domain (LIM motif) II: 345-506 bp, putative
protein kinase domain: 1131-1916 bp."
/product="LIM kinase"
/protein_id="BAA05371.1"
/translation="MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNAD
WHADCFRCCDCSASLSHQYYEKDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGEL
KYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCYYQTVVTPVIEQILPDSPGSHLP
HTVTLVSIPASSHGKRGLSVSIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIH
VGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHDTLGHGLGPETSPLSSP
AYTPSGEAGSSARQKPVLRSCSIDRSPGAGSLGSPASQRKDLGRSESLRVVCRPHRIF
RPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLE
HPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAY
LHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYT
VVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGF
LDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQLEQL
DRGFWETYRRGESGLPAHPEVPD"
regulatory 3235..3240
/regulatory_class="polyA_signal_sequence"
regulatory 3240..3245
/regulatory_class="polyA_signal_sequence"
polyA_site 3262
BASE COUNT 632 a 1051 c 949 g 630 t
ORIGIN
1 gcgccgagcc ggtttccccg ccggtgtccg agaggcgccc ccggcccggc cgcccccagc
61 cccagccccg ccgggccccg ccccccgtcg agtgcatgag gttgacgcta ctttgttgca
121 cctggaggga agaacgtatg ggagaggaag gaagcgagtt gcccgtgtgt gcaagctgcg
181 gccagaggat ctatgatggc cagtacctcc aggccctgaa cgcggactgg cacgcagact
241 gcttcaggtg ttgtgactgc agtgcctccc tgtcgcacca gtactatgag aaggatgggc
301 agctcttctg caagaaggac tactgggccc gctatggcga gtcctgccat gggtgctctg
361 agcaaatcac caagggactg gttatggtgg ctggggagct gaagtaccac cccgagtgtt
421 tcatctgcct cacgtgtggg acctttatcg gtgacgggga cacctacacg ctggtggagc
481 actccaagct gtactgcggg cactgctact accagactgt ggtgaccccc gtcatcgagc
541 agatcctgcc tgactcccct ggctcccacc tgccccacac cgtcaccctg gtgtccatcc
601 cagcctcatc tcatggcaag cgtggacttt cagtctccat tgaccccccg cacggcccac
661 cgggctgtgg caccgagcac tcacacaccg tccgcgtcca gggagtggat ccgggctgca
721 tgagcccaga tgtgaagaat tccatccacg tcggagaccg gatcttggaa atcaatggca
781 cgcccatccg aaatgtgccc ctggacgaga ttgacctgct gattcaggaa accagccgcc
841 tgctccagct gaccctcgag catgaccctc acgatacact gggccacggg ctggggcctg
901 agaccagccc cctgagctct ccggcttata ctcccagcgg ggaggcgggc agctctgccc
961 ggcagaaacc tgtcttgagg agctgcagca tcgacaggtc tccgggcgct ggctcactgg
1021 gctccccggc ctcccagcgc aaggacctgg gtcgctctga gtccctccgc gtagtctgcc
1081 ggccacaccg catcttccgg ccgtcggacc tcatccacgg ggaggtgctg ggcaagggct
1141 gcttcggcca ggctatcaag gtgacacacc gtgagacagg tgaggtgatg gtgatgaagg
1201 agctgatccg gttcgacgag gagacccaga ggacgttcct caaggaggtg aaggtcatgc
1261 gatgcctgga acaccccaac gtgctcaagt tcatcggggt gctctacaag gacaagaggc
1321 tcaacttcat cactgagtac atcaagggcg gcacgctccg gggcatcatc aagagcatgg
1381 acagccagta cccatggagc cagagagtga gctttgccaa ggacatcgca tcagggatgg
1441 cctacctcca ctccatgaac atcatccacc gagacctcaa ctcccacaac tgcctggtcc
1501 gcgagaacaa gaatgtggtg gtggctgact tcgggctggc gcgtctcatg gtggacgaga
1561 agactcagcc tgagggcctg cggagcctca agaagccaga ccgcaagaag cgctacaccg
1621 tggtgggcaa cccctactgg atggcacctg agatgatcaa cggccgcagc tatgatgaga
1681 aggtggatgt gttctccttt gggatcgtcc tgtgcgagat catcgggcgg gtgaacgcag
1741 accctgacta cctgccccgc accatggact ttggcctcaa cgtgcgagga ttcctggacc
1801 gctactgccc cccaaactgc cccccgagct tcttccccat caccgtgcgc tgttgcgatc
1861 tggaccccga gaagaggcca tcctttgtga agctggaaca ctggctggag accctccgca
1921 tgcacctggc cggccacctg ccactgggcc cacagctgga gcagctggac agaggtttct
1981 gggagaccta ccggcgcggc gagagcggac tgcctgccca ccctgaggtc cccgactgag
2041 ccagggccac tcagctgccc ctgtccccac ctctggagaa tccaccccca ccagattcct
2101 ccgcgggagg tggccctcag ctgggacagt ggggacccag gcttctcctc agagccaggc
2161 cctgacttgc cttctcccac cccgtggacc gcttcccctg ccttctctct gccgtggccc
2221 agagccggcc cagctgcaca cacacaccat gctctcgccc tgctgtaacc tctgtcttgg
2281 cagggctgtc ccctcttgct tctccttgca tgagctggag ggcctgtgtg agttacgccc
2341 ctttccacac gccgctgccc cagcaaccct gttcacgctc cacctgtctg gtccatagct
2401 ccctggaggc tgggccagga ggcagcctcc gaaccatgcc ccatataacg cttgggtgcg
2461 tgggagggcg cacatcaggg cagaggccaa gttccaggtg tctgtgttcc caggaaccaa
2521 atggggagtc tggggcccgt tttcccccca gggggtgtct aggtagcaac aggtatcgag
2581 gactctccaa acccccaaag cagagagagg gctgatccca tggggcggag gtccccagtg
2641 gctgagcaaa cagccccttc tctcgctttg ggtctttttt ttgtttcttt cttaaagcca
2701 ctttagtgag aagcaggtac caagcctcag ggtgaagggg gtcccttgag ggagcgtgga
2761 gctgcggtgc cctggccggc gatggggagg agccggctcc ggcagtgaga ggataggcac
2821 agtggaccgg gcaggtgtcc accagcagct cagcccctgc agtcatctca gagccccttc
2881 ccgggcctct cccccaaggc tccctgcccc tcctcatgcc cctctgtcct ctgcgttttt
2941 tctgtgtaat ctatttttta agaagagttt gtattatttt ttcatacggc tgcagcagca
3001 gctgccaggg gcttgggatt ttatttttgt ggcgggcggg ggtgggaggg ccattttgtc
3061 actttgcctc agttgagcat ctaggaagta ttaaaactgt gaagctttct cagtgcactt
3121 tgaacctgga aaacaatccc aacaggcccg tgggaccatg acttagggag gtgggaccca
3181 cccaccccca tccaggaacc gtgacgtcca aggaaccaaa cccagacgca gaacaataaa
3241 ataaattccg tactccccac cc
//